PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009801047.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 514aa    MW: 57305.7 Da    PI: 6.3774
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009801047.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2218.6e-07263284223
                     EETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   2 kCpdCgksFsrksnLkrHirtH 23 
                      C++Cgk F+r  nL+ H+r H
  XP_009801047.1 263 FCTICGKGFKRDANLRMHMRGH 284
                     6*******************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.29E-5260287No hitNo description
SMARTSM003550.0026262284IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.03262289IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.607.3E-6263313IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280264284IPR007087Zinc finger, C2H2
SMARTSM00355100311344IPR015880Zinc finger, C2H2-like
SMARTSM0035525349371IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010044Biological Processresponse to aluminum ion
GO:0010447Biological Processresponse to acidic pH
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 514 aa     Download sequence    Send to blast
MDPDDSLSED PWTKPSSSGN ELLKIVPSDN HSFTNFNLHA QKWEGSSYLD QQTRIEQQFS  60
GFTQPKHTYQ MDQHGNQMNE NHDSTSTKDW DPSNLLNNLS FLEQKIHQLQ ELVHLIVGRR  120
GQTGLQGNDL IVQQQQLITA DLTSIIVQLV STAGSLLPTM KHSLSSVSHA ASQLVQFGGV  180
TVPSATCTNG GGLPCNDGGV TKVEDQSNHV DQLRDCGIEQ SHAVDGHESK DEDEAEEEEN  240
LPPGSYEILQ LEKEEILAPH THFCTICGKG FKRDANLRMH MRGHGDEYKT PAALAKPHKE  300
PSSEPTLIKR YSCPNVGCKR NKEHKKFQPL KTILCVKNHY KRTHCEKAYT CSRCNIKKFS  360
VIADLKTHEK HCGKDKWLCS CGTTFSRKDK LFGHIALFQG HTPAVPLDET KGSAGTSDRG  420
QTSEVTMKAR QEDFKVNASH GNEFQDPRDI KSAADDPGSY FSPLNFDTSN LNGFQEFPRP  480
PFDESDSSFS FLLSGSCEYP PHKAAKYMSS TELE
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269|PubMed:17535918, ECO:0000269|PubMed:18826429, ECO:0000269|PubMed:19321711, ECO:0000269|PubMed:23935008}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00196ampDAPTransfer from AT1G34370Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269|PubMed:17535918}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB8117810.0AB811781.1 Nicotiana tabacum NtSTOP1 mRNA for STOP1-like protein, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009801047.10.0PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1
SwissprotQ9C8N50.0STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBLA0A1S3YYC80.0A0A1S3YYC8_TOBAC; protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
TrEMBLA0A1U7YAA50.0A0A1U7YAA5_NICSY; protein SENSITIVE TO PROTON RHIZOTOXICITY 1
STRINGXP_009801047.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA47542441
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G34370.21e-169C2H2 family protein
Publications ? help Back to Top
  1. Kobayashi Y, et al.
    Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions.
    Plant Physiol., 2013. 163(1): p. 180-92
    [PMID:23839867]
  2. Yokosho K,Yamaji N,Ma JF
    Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench).
    Plant Cell Physiol., 2014. 55(12): p. 2077-91
    [PMID:25273892]
  3. Geng X, et al.
    LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.
    Plant J., 2017. 90(3): p. 491-504
    [PMID:28181322]
  4. Balzergue C, et al.
    Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation.
    Nat Commun, 2017. 8: p. 15300
    [PMID:28504266]
  5. Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A
    Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation.
    Front Plant Sci, 2017. 8: p. 822
    [PMID:28567051]
  6. Jiang F, et al.
    Identification and characterization of suppressor mutants of stop1.
    BMC Plant Biol., 2017. 17(1): p. 128
    [PMID:28738784]
  7. Daspute AA, et al.
    Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
    Front Plant Sci, 2017. 8: p. 1358
    [PMID:28848571]
  8. Sharma A,Wai CM,Ming R,Yu Q
    Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis.
    Genome Biol Evol, 2017. 9(9): p. 2170-2190
    [PMID:28922793]
  9. Zhang Y, et al.
    The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 118
    [PMID:29491872]