PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf04745g02009.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family NAC
Protein Properties Length: 451aa    MW: 51231.8 Da    PI: 9.4556
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf04745g02009.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM179.11.2e-55141411128
                       NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWka 85 
                               lppGfrFhPtdeel+++yL kkv + ++++ ++i+evd++k+ePw+Lp k+k +ekewyfFs rd+ky+tg r+nrat++gyWka
  Niben101Scf04745g02009.1  14 LPPGFRFHPTDEELITYYLLKKVLDGNFTA-RAIAEVDLNKCEPWELPGKAKMGEKEWYFFSLRDRKYPTGLRTNRATEAGYWKA 97 
                               79*************************999.89***************99999******************************** PP

                       NAM  86 tgkdkevlsk.kgelvglkktLvfykgrapkgektdWvmheyrl 128
                               tgkd+e++s+ + +lvg+kktLvfy+grapkgek++Wvmheyrl
  Niben101Scf04745g02009.1  98 TGKDREIYSSkTCALVGMKKTLVFYRGRAPKGEKSNWVMHEYRL 141
                               ********9745567***************************98 PP

2NAM136.51.7e-4214826117128
                       NAM  17 eyLkk..kvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk.kge 98 
                               +y+ +  kv + ++++ ++i+evd++k+ePw+Lp k+k +ekewyfFs rd+ky+tg r+nrat++gyWkatgkd+e++s+ + +
  Niben101Scf04745g02009.1 148 HYISRssKVLDGNFTA-RAIAEVDLNKCEPWELPGKAKMGEKEWYFFSLRDRKYPTGLRTNRATEAGYWKATGKDREIYSSkTCA 231
                               5665511455555666.78***************99999****************************************974556 PP

                       NAM  99 lvglkktLvfykgrapkgektdWvmheyrl 128
                               lvg+kktLvfy+grapkgek++Wvmheyrl
  Niben101Scf04745g02009.1 232 LVGMKKTLVFYRGRAPKGEKSNWVMHEYRL 261
                               7***************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019414.18E-6012149IPR003441NAC domain
PROSITE profilePS5100555.78614163IPR003441NAC domain
PfamPF023651.2E-2815141IPR003441NAC domain
SuperFamilySSF1019412.35E-48154286IPR003441NAC domain
PROSITE profilePS5100538.681166286IPR003441NAC domain
PfamPF023652.0E-16175261IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 451 aa     Download sequence    Send to blast
MDNYQHFDCS DGNLPPGFRF HPTDEELITY YLLKKVLDGN FTARAIAEVD LNKCEPWELP  60
GKAKMGEKEW YFFSLRDRKY PTGLRTNRAT EAGYWKATGK DREIYSSKTC ALVGMKKTLV  120
FYRGRAPKGE KSNWVMHEYR LDGKFAYHYI SRSSKVLDGN FTARAIAEVD LNKCEPWELP  180
GKAKMGEKEW YFFSLRDRKY PTGLRTNRAT EAGYWKATGK DREIYSSKTC ALVGMKKTLV  240
FYRGRAPKGE KSNWVMHEYR LDGKFAYHYI SRSSKDEWVI SRVFQKNGST VGGNKKRLSS  300
SINMYQEVSS PSSVSQLPPL LDSSPYSTTA SSAVINADRE SFKKEHVPCF STTATHSFDP  360
TSSVFDISSN SLHALPPPSF SAILDSSTNF THYTRNSTFP SLRSLHENLQ LPLFSSGAPA  420
MHGGFSASMA NWPVPEAQKV EQSELDCMWG Y
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A9e-491328916168NO APICAL MERISTEM PROTEIN
1ut4_B9e-491328916168NO APICAL MERISTEM PROTEIN
1ut7_A9e-491328916168NO APICAL MERISTEM PROTEIN
1ut7_B9e-491328916168NO APICAL MERISTEM PROTEIN
4dul_A9e-491328916168NAC domain-containing protein 19
4dul_B9e-491328916168NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator of STM and KNAT6. Involved in molecular mechanisms regulating shoot apical meristem (SAM) formation during embryogenesis and organ separation. Required for the fusion of septa of gynoecia along the length of the ovaries. Activates the shoot formation in callus in a STM-dependent manner. Controls leaf margin development and required for leaf serration. Involved in axillary meristem initiation and separation of the meristem from the main stem. Regulates the phyllotaxy throughout the plant development. Seems to act as an inhibitor of cell division. {ECO:0000269|PubMed:10079219, ECO:0000269|PubMed:10750709, ECO:0000269|PubMed:12163400, ECO:0000269|PubMed:12492830, ECO:0000269|PubMed:12610213, ECO:0000269|PubMed:15202996, ECO:0000269|PubMed:15294871, ECO:0000269|PubMed:15500463, ECO:0000269|PubMed:15723790, ECO:0000269|PubMed:16798887, ECO:0000269|PubMed:17098808, ECO:0000269|PubMed:17122068, ECO:0000269|PubMed:17251269, ECO:0000269|PubMed:17287247, ECO:0000269|PubMed:9212461}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By BRM and SYD, at the chromatin level, and conferring a very specific spatial expression pattern. Precise spatial regulation by post-transcriptional repression directed by the microRNA miR164. {ECO:0000269|PubMed:15202996, ECO:0000269|PubMed:15294871, ECO:0000269|PubMed:15723790, ECO:0000269|PubMed:16854978, ECO:0000269|PubMed:17251269, ECO:0000269|PubMed:17287247}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016509208.10.0PREDICTED: protein CUP-SHAPED COTYLEDON 2-like
SwissprotO040179e-96NAC98_ARATH; Protein CUP-SHAPED COTYLEDON 2
TrEMBLA0A1S4D7900.0A0A1S4D790_TOBAC; protein CUP-SHAPED COTYLEDON 2-like
STRINGXP_009615029.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA15224279
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G53950.19e-96NAC family protein
Publications ? help Back to Top
  1. Wang YX
    Characterization of a novel Medicago sativa NAC transcription factor gene involved in response to drought stress.
    Mol. Biol. Rep., 2013. 40(11): p. 6451-8
    [PMID:24057250]
  2. Kamiuchi Y,Yamamoto K,Furutani M,Tasaka M,Aida M
    The CUC1 and CUC2 genes promote carpel margin meristem formation during Arabidopsis gynoecium development.
    Front Plant Sci, 2014. 5: p. 165
    [PMID:24817871]
  3. Gonçalves B, et al.
    A conserved role for CUP-SHAPED COTYLEDON genes during ovule development.
    Plant J., 2015. 83(4): p. 732-42
    [PMID:26119568]
  4. Du Q,Wang H
    The role of HD-ZIP III transcription factors and miR165/166 in vascular development and secondary cell wall formation.
    Plant Signal Behav, 2015. 10(10): p. e1078955
    [PMID:26340415]
  5. Vialette-Guiraud AC, et al.
    A Conserved Role for the NAM/miR164 Developmental Module Reveals a Common Mechanism Underlying Carpel Margin Fusion in Monocarpous and Syncarpous Eurosids.
    Front Plant Sci, 2015. 6: p. 1239
    [PMID:26793217]
  6. Cui X, et al.
    REF6 recognizes a specific DNA sequence to demethylate H3K27me3 and regulate organ boundary formation in Arabidopsis.
    Nat. Genet., 2016. 48(6): p. 694-9
    [PMID:27111035]
  7. Blein T,Pautot V,Laufs P
    Combinations of Mutations Sufficient to Alter Arabidopsis Leaf Dissection.
    Plants (Basel), 2013. 2(2): p. 230-47
    [PMID:27137374]
  8. Biot E, et al.
    Multiscale quantification of morphodynamics: MorphoLeaf software for 2D shape analysis.
    Development, 2016. 143(18): p. 3417-28
    [PMID:27387872]
  9. Zheng M, et al.
    Chloroplast Translation Initiation Factors Regulate Leaf Variegation and Development.
    Plant Physiol., 2016. 172(2): p. 1117-1130
    [PMID:27535792]
  10. Balkunde R,Kitagawa M,Xu XM,Wang J,Jackson D
    SHOOT MERISTEMLESS trafficking controls axillary meristem formation, meristem size and organ boundaries in Arabidopsis.
    Plant J., 2017. 90(3): p. 435-446
    [PMID:28161901]
  11. Koyama T,Sato F,Ohme-Takagi M
    Roles of miR319 and TCP Transcription Factors in Leaf Development.
    Plant Physiol., 2017. 175(2): p. 874-885
    [PMID:28842549]
  12. González-Carranza ZH, et al.
    HAWAIIAN SKIRT controls size and floral organ number by modulating CUC1 and CUC2 expression.
    PLoS ONE, 2017. 12(9): p. e0185106
    [PMID:28934292]
  13. Wilson-Sánchez D,Martínez-López S,Navarro-Cartagena S,Jover-Gil S,Micol JL
    Members of the DEAL subfamily of the DUF1218 gene family are required for bilateral symmetry but not for dorsoventrality in Arabidopsis leaves.
    New Phytol., 2018. 217(3): p. 1307-1321
    [PMID:29139551]
  14. Gonçalves B, et al.
    GDP-L-fucose is required for boundary definition in plants.
    J. Exp. Bot., 2017. 68(21-22): p. 5801-5811
    [PMID:29186469]
  15. Sha S, et al.
    To be serrate or pinnate: diverse leaf forms of yarrows (Achillea) are linked to differential expression patterns of NAM genes.
    Ann. Bot., 2018. 121(2): p. 255-266
    [PMID:29267935]
  16. Maugarny-Calès A, et al.
    Dissecting the pathways coordinating patterning and growth by plant boundary domains.
    PLoS Genet., 2019. 15(1): p. e1007913
    [PMID:30677017]