PlantRegMap
Plant Transcription Factor Database
PlantTFDB
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr8g089310.1
Common NameMTR_8g089310
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family LSD
Protein Properties Length: 224aa    MW: 23979.7 Da    PI: 9.0388
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr8g089310.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD143.93.9e-145478125
          zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                     C+gCr++L YPrGA++V+CalC+t+
  Medtr8g089310.1 54 CNGCRNTLLYPRGATNVCCALCNTI 78
                     ***********************97 PP

2zf-LSD149.28.6e-1693117125
          zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                      CggCrtlL+Y+rGA+sVRC++C+tV
  Medtr8g089310.1  93 CGGCRTLLMYTRGATSVRCSCCHTV 117
                      ************************9 PP

3zf-LSD1474.1e-15131154124
          zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdt 24 
                      Cg+Crt+L+YP+GApsV+Ca+C+ 
  Medtr8g089310.1 131 CGNCRTTLMYPYGAPSVKCAVCHY 154
                      **********************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010531.5E-125181IPR005735Zinc finger, LSD1-type
PfamPF069431.3E-115478IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010538.8E-1790119IPR005735Zinc finger, LSD1-type
PfamPF069433.7E-1393117IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010537.2E-12128157IPR005735Zinc finger, LSD1-type
PfamPF069433.3E-14131155IPR005735Zinc finger, LSD1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000303Biological Processresponse to superoxide
GO:0001666Biological Processresponse to hypoxia
GO:0002240Biological Processresponse to molecule of oomycetes origin
GO:0009626Biological Processplant-type hypersensitive response
GO:0009862Biological Processsystemic acquired resistance, salicylic acid mediated signaling pathway
GO:0010104Biological Processregulation of ethylene-activated signaling pathway
GO:0010310Biological Processregulation of hydrogen peroxide metabolic process
GO:0010602Biological Processregulation of 1-aminocyclopropane-1-carboxylate metabolic process
GO:0010618Biological Processaerenchyma formation
GO:0043069Biological Processnegative regulation of programmed cell death
Sequence ? help Back to Top
Protein Sequence    Length: 224 aa     Download sequence    Send to blast
MKKIDFVEGF SHFVKVIKGR CEENNIGSRR RRSHKEGRKE HGPGAAAMQS QLVCNGCRNT  60
LLYPRGATNV CCALCNTITA VPPPGMDMSQ LYCGGCRTLL MYTRGATSVR CSCCHTVNLA  120
PVSNQVAHVP CGNCRTTLMY PYGAPSVKCA VCHYITNINM SNGRLPIPGH RPHGTTDSGM  180
LPSTSTSMPQ SQSQTVVVEN PMSVDSSGKL VSNVVVGVTT DKK*
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.57260.0leaf| root| seed| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in cotyledons, roots, rosette leaves, stems, inflorescences and flowers. {ECO:0000269|PubMed:20456049}.
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr8g089310.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0533680.0BT053368.1 Medicago truncatula clone MTYFP_FQ_FR_FS1G-L-7 unknown mRNA.
GenBankBT1464960.0BT146496.1 Medicago truncatula clone JCVI-FLMt-10N12 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024629307.11e-125protein LSD1
SwissprotP940773e-74LSD1_ARATH; Protein LSD1
TrEMBLG7L9L51e-163G7L9L5_MEDTR; LSD1-type zinc finger protein
STRINGAET044891e-164(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF40273361
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.72e-73LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  3. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  4. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  5. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]