PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr4g127930.1
Common NameMTR_4g127930
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family AP2
Protein Properties Length: 513aa    MW: 55815.2 Da    PI: 8.2202
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr4g127930.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP248.13e-15161220155
              AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                      s y+GV++++++gr++A+++d  +   g  ++ ++++lg ++ +e+Aa+a++ a++k++g
  Medtr4g127930.1 161 SIYRGVTRHRWTGRYEAHLWDnSCRrEGqsRKgRQVYLGGYDKEEKAARAYDLAALKYWG 220
                      57*******************666664477446*************************98 PP

2AP247.25.3e-15263314155
              AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                      s y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  Medtr4g127930.1 263 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDIAAIKFRG 314
                      57****************988532...5************************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000183.44E-23161230No hitNo description
SuperFamilySSF541711.37E-17161230IPR016177DNA-binding domain
PfamPF008472.9E-12161220IPR001471AP2/ERF domain
SMARTSM003807.3E-30162234IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.105.2E-16162229IPR001471AP2/ERF domain
PROSITE profilePS5103219.23162228IPR001471AP2/ERF domain
PRINTSPR003672.1E-6163174IPR001471AP2/ERF domain
SuperFamilySSF541717.19E-18263324IPR016177DNA-binding domain
PfamPF008476.6E-10263314IPR001471AP2/ERF domain
CDDcd000182.10E-25263324No hitNo description
PROSITE profilePS5103219.045264322IPR001471AP2/ERF domain
SMARTSM003801.5E-33264328IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.3E-18264323IPR001471AP2/ERF domain
PRINTSPR003672.1E-6304324IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009845Biological Processseed germination
GO:0040019Biological Processpositive regulation of embryonic development
GO:0048364Biological Processroot development
GO:0060772Biological Processleaf phyllotactic patterning
GO:0060774Biological Processauxin mediated signaling pathway involved in phyllotactic patterning
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 513 aa     Download sequence    Send to blast
MDKSSSSPPT NTNNTSLAFS LSNNNFPNPS HSSSSHLSLF HSFTPYPSSI IPPSLTLTGS  60
NNPVEASPEA TDGGTTNLSI FTGGHKFEDF LGSSVAPTRT AAATCAPTQL QQFSTDNDVY  120
NSELKKTIAA CFPGGYPTEP NSEPQKPSPK KTVDTFGQRT SIYRGVTRHR WTGRYEAHLW  180
DNSCRREGQS RKGRQVYLGG YDKEEKAARA YDLAALKYWG PTTTTNFPIS NYEKEIDDMK  240
NMTRQEFVAS LRRKSSGFSR GASIYRGVTR HHQHGRWQAR IGRVAGNKDL YLGTFSTQEE  300
AAEAYDIAAI KFRGLNAVTN FDMSRYDVKS IANCSLPIGG LSNKNNKNST DCVSETKINE  360
PIQSDEIDHP SSTSSATTLS FALPIKQDPS TDYWSNILGF HNNPSAVTTT TIPFNMDFSA  420
HVPSNTNSDN PHNAAFFSGS GIFVQQQNMN GSSGSNSSSS SSASTSSIPF ATPIFSLNSN  480
SSSYGNGNNW IGHTFQTHAK PSLFQTPIFG ME*
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.176730.0root| seed
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Present in inflorescence meristem and later in young floral mersitems. Expressed in sepal, petal, stamen and carpel primordia. In petal, progressively confined to petal margin and epidermal cells. Restricted to sporogenous tissue in the stamen and to the medial ridge of the carpel. Present in tissues that develop from this ridge, such as placenta and ovule primordia. In ovules, first expressed in distal part of the funiculus and the outer integument, before being confined to the funiculus. {ECO:0000269|PubMed:15988559}.
UniprotTISSUE SPECIFICITY: Expressed in roots, seedlings, inflorescence, and siliques. Also detected at low levels in leaves. {ECO:0000269|PubMed:15988559}.
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Involved in the regulation of floral organs size. {ECO:0000250, ECO:0000269|PubMed:15988559}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr4g127930.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1358010.0AC135801.24 Medicago truncatula chromosome 8 clone mth2-23o16, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003610101.20.0AP2-like ethylene-responsive transcription factor AIL5
SwissprotQ6PQQ31e-155AIL5_ARATH; AP2-like ethylene-responsive transcription factor AIL5
TrEMBLG7JVD90.0G7JVD9_MEDTR; AP2-like ethylene-responsive transcription factor
STRINGAES922980.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF125622735
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G57390.11e-143AINTEGUMENTA-like 5
Publications ? help Back to Top
  1. Todd J,Post-Beittenmiller D,Jaworski JG
    KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana.
    Plant J., 1999. 17(2): p. 119-30
    [PMID:10074711]
  2. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  3. Molitor AM,Bu Z,Yu Y,Shen WH
    Arabidopsis AL PHD-PRC1 complexes promote seed germination through H3K4me3-to-H3K27me3 chromatin state switch in repression of seed developmental genes.
    PLoS Genet., 2014. 10(1): p. e1004091
    [PMID:24465219]
  4. Feng J,Chen D,Berr A,Shen WH
    ZRF1 Chromatin Regulators Have Polycomb Silencing and Independent Roles in Development.
    Plant Physiol., 2016. 172(3): p. 1746-1759
    [PMID:27630184]
  5. Santuari L, et al.
    The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots.
    Plant Cell, 2016. 28(12): p. 2937-2951
    [PMID:27920338]
  6. Du Y,Scheres B
    PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714
    [PMID:29078398]