PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr4g121020.1
Common NameMTR_4g121020
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family ARR-B
Protein Properties Length: 682aa    MW: 74269.1 Da    PI: 6.0175
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr4g121020.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like91.95.3e-29215268155
          G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                      kpr++W+ eLH++Fv+av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl
  Medtr4g121020.1 215 KPRVVWSVELHQQFVDAVDQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 268
                      79*******************.********************************8 PP

2Response_reg76.31.2e-25371451109
                      EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHT CS
     Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealka 92 
                      vl+vdD+p+ +++l+++l+   y ev+ +  +e al ll+e++  +D+++ D+ mp+mdG++ll++i  e  +lp+i+++a + ++ + + +  
  Medtr4g121020.1  37 VLVVDDDPTCLMILEKMLRTCLY-EVTKCNRAETALSLLRENKngFDIVISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDGKSVVMKGVTH 128
                      89*********************.***************999999**********************6654.8********************* PP

                      TESEEEESS--HHHHHH CS
     Response_reg  93 GakdflsKpfdpeelvk 109
                      Ga d+l Kp+ +e+l +
  Medtr4g121020.1 129 GACDYLIKPVRIEALKN 145
                      *************9986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363923.0E-18015673IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23003.5E-4234169No hitNo description
SuperFamilySSF521723.42E-3534156IPR011006CheY-like superfamily
SMARTSM004481.8E-3035147IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011042.51436151IPR001789Signal transduction response regulator, receiver domain
PfamPF000725.4E-2337145IPR001789Signal transduction response regulator, receiver domain
CDDcd001563.48E-2738150No hitNo description
PROSITE profilePS5129411.502212271IPR017930Myb domain
SuperFamilySSF466894.3E-20212272IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.3E-30214273IPR009057Homeodomain-like
TIGRFAMsTIGR015572.8E-25215268IPR006447Myb domain, plants
PfamPF002499.6E-8217267IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0010082Biological Processregulation of root meristem growth
GO:0010119Biological Processregulation of stomatal movement
GO:0010150Biological Processleaf senescence
GO:0071368Biological Processcellular response to cytokinin stimulus
GO:0080113Biological Processregulation of seed growth
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 682 aa     Download sequence    Send to blast
MMNLSNNGKG SISTVTSTAT TMKSGEGSDQ FPAGLRVLVV DDDPTCLMIL EKMLRTCLYE  60
VTKCNRAETA LSLLRENKNG FDIVISDVHM PDMDGFKLLE HIGLEMDLPV IMMSADDGKS  120
VVMKGVTHGA CDYLIKPVRI EALKNIWQHV VRKKKNEWKD TEQSGSADEG DRHPKASDDA  180
DYSSSANEGN WRNSRKRRDD EEEGDDRDDS STLKKPRVVW SVELHQQFVD AVDQLGIDKA  240
VPKKILELMN VPGLTRENVA SHLQKYRLYL RRLSGVSQHQ NNSFLSPQEA SFGTISSMNG  300
LDLQTLAAAG QLPAQSLATL QAAGLGRSTV KSGLPMPLMD QRNLFSFENP RLRFGEGQQQ  360
LLNGSNNKPT NLLHGVPTNM EPKQLANLHQ SAAQSLGNMN MRVPASATQG NPLLMQMAQS  420
QPRGPMLSEN TGSHVPRLPN LLGQSTVSNG ISDGLMGRNN MASSSRAPSF NPVPQSSSFL  480
NFPMNQSTEM SVSNFPLGST PGISSITTKG SFQAEVNSGI KGSAGFPSYD IFNELNHQKS  540
RDWGMTNQGL MYDSSSHANP LHGNIDVSPS VLVHQGFSSA QQTGHSRDAS LLGKSPFSLG  600
EGLEQGNLQN GGGQHFNPLY VENLTRVKAE RVPDASSHTD LFPDHFGQDD LMSALLKQQE  660
GIGQGENEFD FDGYSLDNIP V*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A3e-22214274464ARR10-B
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.90460.0flower| glandular trichome| leaf| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Detected in the whole plant. Predominantly expressed in pollen. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:15173562, ECO:0000269|PubMed:9891419}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00054PBMTransfer from AT4G16110Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr4g121020.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013458294.10.0two-component response regulator ARR2 isoform X1
SwissprotQ9ZWJ90.0ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A072V2J30.0A0A072V2J3_MEDTR; Two-component response regulator
STRINGGLYMA07G37220.10.0(Glycine max)
STRINGGLYMA17G03380.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF39583458
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.10.0response regulator 2
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  3. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  4. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  5. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  6. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  7. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  8. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  9. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  10. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]