PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr4g108370.1
Common NameMTR_4g108370
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family TCP
Protein Properties Length: 438aa    MW: 47446.9 Da    PI: 8.0387
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr4g108370.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP129.82.7e-40912432116
              TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec.eaesssssasnsssg...... 88 
                      ++k+++++++hTkv+gR+RR+R++a+caar+F+L++eLG+++d++tieWLlqqa+pa++++tgt++++a+++  + s +ss+s+ s +      
  Medtr4g108370.1  91 PPKRTSTKDRHTKVEGRGRRIRMPALCAARVFQLTRELGHKSDGETIEWLLQQAEPAVIAATGTGTIPANFTsLNISLRSSGSSMSVPsqlrss 184
                      789******************************************************************9998777777777755555666666 PP

              TCP  89 ..........................kaaksaakskksqksaasalnlakesr.....a 116
                                                +++++++  ++++++ +++l+ ++e r     +
  Medtr4g108370.1 185 yfnpnfslqqrrtlfpgiglspsdnnSNNNTSMLLNFQSNNLTNMLQAKQEVRdgntnS 243
                      77777778888888888887777665333333344444444444554444444333221 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036345.5E-4195246IPR005333Transcription factor, TCP
PROSITE profilePS5136927.86997151IPR017887Transcription factor TCP subgroup
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008283Biological Processcell proliferation
GO:0009735Biological Processresponse to cytokinin
GO:0009737Biological Processresponse to abscisic acid
GO:0009739Biological Processresponse to gibberellin
GO:0010029Biological Processregulation of seed germination
GO:0010229Biological Processinflorescence development
GO:0031347Biological Processregulation of defense response
GO:0005634Cellular Componentnucleus
Sequence ? help Back to Top
Protein Sequence    Length: 438 aa     Download sequence    Send to blast
MDGGDDLHHH HHHQHHQHHH QHQQQQRQNF PFQLLEKKED NQEAASCSTS SPYPSLAISP  60
TEPSTSNSNR SNQLVPASTP TTSDPANKKP PPKRTSTKDR HTKVEGRGRR IRMPALCAAR  120
VFQLTRELGH KSDGETIEWL LQQAEPAVIA ATGTGTIPAN FTSLNISLRS SGSSMSVPSQ  180
LRSSYFNPNF SLQQRRTLFP GIGLSPSDNN SNNNTSMLLN FQSNNLTNML QAKQEVRDGN  240
TNSNANANAP SSSTTLDLSE TSGEESMGGR KRRTSSGGSE QDLSSLQHQM GSYLMQSSAG  300
SIPASHTQIP ANIWMVANSN NQIMSGGDPI WTFPSVNNSA AALYRGAVST SGLHFMNFPQ  360
PMALLPGQQL GNSSGGGGGG GNINMNMNMN EGHLSMLAGL SPYRPVSDHH QQHHQPSGSQ  420
SHHHRSGSHE HDDRHDN*
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the vascular tissues of the embryo (PubMed:17953649). Expressed in young proliferating tissues (PubMed:21668538). {ECO:0000269|PubMed:17953649, ECO:0000269|PubMed:21668538}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved the regulation of plant development. Together with TCP15, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in leaf and floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Involved in the regulation of seed germination. May regulate the activation of embryonic growth potential during seed germination (PubMed:17953649, PubMed:22155632). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742). Involved in positive regulation of plant defense. Represses jasmonate (JA) response to promote disease resistance. Regulates the plant immune system by transcriptionally repressing a subset of JA-responsive genes (PubMed:28132837). {ECO:0000269|PubMed:17953649, ECO:0000269|PubMed:21668538, ECO:0000269|PubMed:22155632, ECO:0000269|PubMed:22267487, ECO:0000269|PubMed:24689742, ECO:0000269|PubMed:25655823, ECO:0000269|PubMed:25757472, ECO:0000269|PubMed:28132837}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00396DAPTransfer from AT3G47620Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr4g108370.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced during seed imbibition (PubMed:17953649). Circadian-regulation with the lowest expression in the middle of the dark period (PubMed:17953649). {ECO:0000269|PubMed:17953649}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1463290.0AC146329.20 Medicago truncatula chromosome 8 clone mth2-5i21, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003609053.10.0transcription factor TCP15
SwissprotQ93Z002e-63TCP14_ARATH; Transcription factor TCP14
TrEMBLG7JQY30.0G7JQY3_MEDTR; Putative transcription factor TCP family
STRINGAES912500.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF21203280
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G69690.17e-48TCP family protein
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Steiner E, et al.
    The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin.
    Plant Physiol., 2016. 171(2): p. 1485-94
    [PMID:27208284]
  3. Yang L, et al.
    Pseudomonas syringae Type III Effector HopBB1 Promotes Host Transcriptional Repressor Degradation to Regulate Phytohormone Responses and Virulence.
    Cell Host Microbe, 2017. 21(2): p. 156-168
    [PMID:28132837]
  4. Zhang N, et al.
    MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis.
    Plant J., 2018. 93(1): p. 66-78
    [PMID:29086441]
  5. Mazur MJ, et al.
    Arabidopsis TCP Transcription Factors Interact with the SUMO Conjugating Machinery in Nuclear Foci.
    Front Plant Sci, 2017. 8: p. 2043
    [PMID:29250092]