PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010106896.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Moraceae; Morus
Family AP2
Protein Properties Length: 669aa    MW: 75029.4 Da    PI: 7.3093
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010106896.1genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2391.9e-12332388155
             AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng.krkrfslgkfgtaeeAakaaiaarkkleg 55 
                     s+y+GV++++++gr++A+++d  ++  g  rk  + g ++ +e+Aa+a++ a++k++g
  XP_010106896.1 332 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqSRKGRQ-GGYDMEEKAARAYDLAALKYWG 388
                     78*******************87776664446655.77******************98 PP

2AP246.87.6e-15431482155
             AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                     s y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  XP_010106896.1 431 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDIAAIKFRG 482
                     57****************988532...5************************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF819951.44E-6159221No hitNo description
CDDcd000185.38E-19332396No hitNo description
SuperFamilySSF541712.22E-14332398IPR016177DNA-binding domain
PfamPF008471.3E-9332388IPR001471AP2/ERF domain
PROSITE profilePS5103217.451333396IPR001471AP2/ERF domain
SMARTSM003801.1E-22333402IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.4E-12333397IPR001471AP2/ERF domain
PRINTSPR003675.2E-6334345IPR001471AP2/ERF domain
SuperFamilySSF541711.5E-17431491IPR016177DNA-binding domain
CDDcd000183.44E-25431492No hitNo description
PfamPF008479.4E-10431482IPR001471AP2/ERF domain
SMARTSM003801.3E-33432496IPR001471AP2/ERF domain
PROSITE profilePS5103219.045432490IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.107.4E-18432490IPR001471AP2/ERF domain
PRINTSPR003675.2E-6472492IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 669 aa     Download sequence    Send to blast
MKSMNNDENN NNSNNNWLGF SLSPNMKMEV PSSDPHHQHH QTLHKSSSSS SSTSSTTVSS  60
SIPSKNFFHS TAVPLPPQHN YGLYYGVDQG ENGGFYSPLS VMPLKSDGSL CIMEAFSRSQ  120
PQAMATSSTP KLEYFFGTHH YESNDREVMA LSLDSMFYNH HDPNTNQNLL NQDHYHHQNP  180
QQQQQQQHQQ QQQHQQQQQQ QQQQQQQQHY SYNYLDTQIP AMANDGVHHE NMKSNWVSRN  240
YCMAENGGES GASNNSNICG TGYGDFQSLS LSMSPGSQSS CVTAASQQIS PSAAVTDRCA  300
VAMDTKKRGP EKVDQKQIVH RKSIDTFGQR TSQYRGVTRH RWTGRYEAHL WDNSCKKEGQ  360
SRKGRQGGYD MEEKAARAYD LAALKYWGPS THINFPLENY QKELEEMKNM TRQEYVAHLR  420
RKSSGFSRGA SIYRGVTRHH QHGRWQARIG RVAGNKDLYL GTFSTQEEAA EAYDIAAIKF  480
RGLNAVTNFD ITRYDVERIM ASNTLLAGDL ARRTKEAGSP GSEAANHNSA TNSVSDEITM  540
SKDNESESDW KMSLYHSSQL LDQKPLSIDT YKTESFSVAP LSMIHQEVED SAKMGTHLSN  600
ASSLVTSLSS SREGSPDKSS HPTLFGMPPS VSKFFTSPTN AVNSWIPTNQ QRPAISMPHM  660
PIFAAWTDT
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010106896.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024028337.10.0AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389141e-171ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLW9S6160.0W9S616_9ROSA; AP2-like ethylene-responsive transcription factor ANT
STRINGXP_010106896.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF91634114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-128AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]