PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010090441.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Moraceae; Morus
Family NAC
Protein Properties Length: 482aa    MW: 53624 Da    PI: 6.331
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010090441.1genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM166.59.3e-52451721128
             NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 
                     l+pGfrFhPtdeelv +yLk+kv gk++++ ++i+evd+yk+ePwdL  k ++k++++e+yfFs  d+ky +g r nrat++gyWkatg+d++v 
  XP_010090441.1  45 LAPGFRFHPTDEELVIYYLKRKVCGKPFRF-NAITEVDVYKSEPWDLAdKsSLKSRDQEYYFFSALDRKYGNGARMNRATNQGYWKATGNDRPVR 138
                     579**************************9.89**************75347888999************************************* PP

             NAM  94 skkgelvglkktLvfykgrapkgektdWvmheyrl 128
                     + ++++vglkktLvf++grap+g++t+Wvmheyr+
  XP_010090441.1 139 H-DSRTVGLKKTLVFHSGRAPDGKRTNWVMHEYRI 172
                     *.999****************************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019419.42E-6039197IPR003441NAC domain
PROSITE profilePS5100557.20845197IPR003441NAC domain
PfamPF023654.2E-2647172IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009555Biological Processpollen development
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:0005730Cellular Componentnucleolus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 482 aa     Download sequence    Send to blast
MGRESSSPAH PSMAPPTLLA LSVPSPPQTT MTKVQTTTTT TPTALAPGFR FHPTDEELVI  60
YYLKRKVCGK PFRFNAITEV DVYKSEPWDL ADKSSLKSRD QEYYFFSALD RKYGNGARMN  120
RATNQGYWKA TGNDRPVRHD SRTVGLKKTL VFHSGRAPDG KRTNWVMHEY RIVDEELEKA  180
GVGAAQDAFV LCRIFHKSNI GPPSGQRYAP FIEEEWDDDD SAVVPGVDNA NEVVARRHAI  240
GGNGHRMYIE SNAHDTLVEG DTVMQDIQST KKALDLPRHD QNVLSACKIE RPDDYPVPCQ  300
VNREDSLDGR PVPGANDQEH LSLVVDRVSS PLLMYKRRRH NDSNSTNCNA SENSSGATQD  360
RGSSVTTAAT TMSTMTTATN KPPTTRNFLS ALVEYSLLES IEPKETTPVP PELDAANLDA  420
SLPPSCVKFI QDLQNEIHQV SIERDTLKFE MMSAQAMINI LQSRIDLLTK ENNDLKRSSQ  480
GV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A9e-49341999170NAC domain-containing protein 19
3swm_B9e-49341999170NAC domain-containing protein 19
3swm_C9e-49341999170NAC domain-containing protein 19
3swm_D9e-49341999170NAC domain-containing protein 19
3swp_A9e-49341999170NAC domain-containing protein 19
3swp_B9e-49341999170NAC domain-containing protein 19
3swp_C9e-49341999170NAC domain-containing protein 19
3swp_D9e-49341999170NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC050 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). Regulates siRNA-dependent post-transcriptional gene silencing (PTGS) through SGS3 expression modulation (PubMed:28207953). Required during pollen development (PubMed:19237690). {ECO:0000269|PubMed:19237690, ECO:0000269|PubMed:24045019, ECO:0000269|PubMed:25578968, ECO:0000269|PubMed:26617990, ECO:0000269|PubMed:28207953}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00612ChIP-seqTransfer from AT3G10490Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010090441.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by type III effector proteins (TTEs) secreted by the pathogenic bacteria P.syringae pv. tomato DC3000 during basal defense. {ECO:0000269|PubMed:16553893}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010090441.10.0NAC domain containing protein 50 isoform X1
SwissprotQ9SQY01e-128NAC52_ARATH; NAC domain containing protein 52
TrEMBLW9R7650.0W9R765_9ROSA; NAC domain-containing protein 78
STRINGXP_010090441.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF81893241
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G10490.21e-124NAC domain containing protein 52
Publications ? help Back to Top
  1. Higgins JD,Ferdous M,Osman K,Franklin FC
    The RecQ helicase AtRECQ4A is required to remove inter-chromosomal telomeric connections that arise during meiotic recombination in Arabidopsis.
    Plant J., 2011. 65(3): p. 492-502
    [PMID:21265901]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Zhang S, et al.
    C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association.
    Cell Discov, 2019.
    [PMID:26617990]
  4. Butel N,Le Masson I,Bouteiller N,Vaucheret H,Elmayan T
    sgs1: a neomorphic nac52 allele impairing post-transcriptional gene silencing through SGS3 downregulation.
    Plant J., 2017. 90(3): p. 505-519
    [PMID:28207953]
  5. Elmayan T, et al.
    Arabidopsis mutants impaired in cosuppression.
    Plant Cell, 1998. 10(10): p. 1747-58
    [PMID:9761800]