PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Manes.03G010500.1.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Crotonoideae; Manihoteae; Manihot
Family ARR-B
Protein Properties Length: 686aa    MW: 75312.8 Da    PI: 6.4698
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Manes.03G010500.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like894.3e-28196249155
              G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                          kpr++W+ eLH++Fv av+qL G +kA+Pk+il+lm+v+ Lt+e+v+SHLQkYRl
  Manes.03G010500.1.p 196 KPRVVWSVELHRKFVAAVNQL-GLDKAVPKKILDLMNVEKLTRENVASHLQKYRL 249
                          79*******************.********************************8 PP

2Response_reg78.81.9e-26201281109
                          EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHH CS
         Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedale 88 
                          vl vdD+p+ + ll+++l++ +y +v++++++ +al++l+e++  +Dl++ D+ mp+mdG++ll+     e++lp+i+++a+++++++ +
  Manes.03G010500.1.p  20 VLAVDDDPTCLLLLETLLRRCQY-NVTTTSQAIAALKMLRENKnkFDLVISDVHMPDMDGFKLLELVGL-EMDLPVIMLSAYSDPKLVMK 107
                          799********************.***************888888*******************87754.558***************** PP

                          HHHTTESEEEESS--HHHHHH CS
         Response_reg  89 alkaGakdflsKpfdpeelvk 109
                           +  Ga d+l Kp+ +eel +
  Manes.03G010500.1.p 108 GITHGACDYLLKPVRMEELKN 128
                          ******************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363926.0E-1611679IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23001.3E-4217170No hitNo description
SuperFamilySSF521726.83E-3717142IPR011006CheY-like superfamily
SMARTSM004482.2E-3318130IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011043.88819134IPR001789Signal transduction response regulator, receiver domain
PfamPF000727.9E-2420128IPR001789Signal transduction response regulator, receiver domain
CDDcd001561.73E-2421134No hitNo description
PROSITE profilePS5129411.565193252IPR017930Myb domain
Gene3DG3DSA:1.10.10.603.1E-30193254IPR009057Homeodomain-like
SuperFamilySSF466899.32E-20193253IPR009057Homeodomain-like
TIGRFAMsTIGR015576.2E-25196249IPR006447Myb domain, plants
PfamPF002493.3E-7198248IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 686 aa     Download sequence    Send to blast
MTVEQGIGEP RDQFPIGMRV LAVDDDPTCL LLLETLLRRC QYNVTTTSQA IAALKMLREN  60
KNKFDLVISD VHMPDMDGFK LLELVGLEMD LPVIMLSAYS DPKLVMKGIT HGACDYLLKP  120
VRMEELKNIW QHVIRRRKFD NKDWNNFDNQ DKLHHGSDET TADHKLNKKR KDQNEDEDED  180
RDDNGHENED PTTQKKPRVV WSVELHRKFV AAVNQLGLDK AVPKKILDLM NVEKLTRENV  240
ASHLQKYRLY LKRISAVANQ QATMAALGSP DASYLQMGPV NGLGFPNLAG TGQFHNATFR  300
SFPPSGMLGR LNSPAALGMR GLPSAGVIQI GHLPTTGQLT SSQSQFQSII HPRNGGNVLQ  360
GMPMSLEFDQ VHSNKVVTYI RDTDVNDTTT PSVSSGFLDA KIMAGSSNGP LLGVSNKSLM  420
LEGNALEAQD GQKFGKQSSL AVASLSLDSG FSSNFLDNGS CNDSWSSSVH STGIQSNSFA  480
LNECFQQATM HPSNIRDCVS TMASQSGNNA SHVSSISSMP IHLQDSKADV HCQIASITSN  540
ARQMINNAPQ RWDDRRQDAS CRSNAVCCSI NSGVPIHGTG NPMGQSLDPN DVILDRTKNF  600
NSTRQPNIVD PSPMKHDEVE NLTMESLMRS NEGYAVGQQN QQGSHVSNNF GSLEDLACVM  660
VKQENKVTAT VGEFAYGAYS LRMSM*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A3e-26192255164ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). Involved in activating SHY2 during meristem growth and controls PIN expression via activation of SHY2 (PubMed:20605455). {ECO:0000250|UniProtKB:Q940D0, ECO:0000269|PubMed:17363254, ECO:0000269|PubMed:20605455}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapManes.03G010500.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021607936.10.0two-component response regulator ARR12-like isoform X1
SwissprotP625981e-142ARR12_ARATH; Two-component response regulator ARR12
TrEMBLA0A2C9W6060.0A0A2C9W606_MANES; Two-component response regulator
STRINGcassava4.1_002915m0.0(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF95634112
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G25180.11e-128response regulator 12
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Cortleven A, et al.
    A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors.
    Plant Physiol., 2014. 164(3): p. 1470-83
    [PMID:24424319]
  3. Kim HJ,Kieber JJ,Schaller GE
    The rice F-box protein KISS ME DEADLY2 functions as a negative regulator of cytokinin signalling.
    Plant Signal Behav, 2013. 8(12): p. e26434
    [PMID:24675172]
  4. Choi SH, et al.
    Gene duplication of type-B ARR transcription factors systematically extends transcriptional regulatory structures in Arabidopsis.
    Sci Rep, 2014. 4: p. 7197
    [PMID:25425016]
  5. Jiang L, et al.
    Strigolactones spatially influence lateral root development through the cytokinin signaling network.
    J. Exp. Bot., 2016. 67(1): p. 379-89
    [PMID:26519957]
  6. Cortleven A, et al.
    Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes.
    Plant Physiol., 2016. 172(1): p. 464-78
    [PMID:27388681]
  7. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  8. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  9. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  10. Kobayashi K,Iwase A
    Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal.
    Plant Signal Behav, 2017. 12(6): p. e1338999
    [PMID:28594268]
  11. Dai X, et al.
    ARR12 promotes de novo shoot regeneration in Arabidopsis thaliana via activation of WUSCHEL expression.
    J Integr Plant Biol, 2017. 59(10): p. 747-758
    [PMID:28681564]
  12. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  13. Yan Z, et al.
    Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1.
    Plant Physiol., 2017. 175(3): p. 1438-1454
    [PMID:28931628]
  14. Bustillo-AvendaƱo E, et al.
    Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis.
    Plant Physiol., 2018. 176(2): p. 1709-1727
    [PMID:29233938]