PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000423596
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family HD-ZIP
Protein Properties Length: 433aa    MW: 47701.1 Da    PI: 6.1412
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000423596genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox55.21.2e-17227280356
                    --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
       Homeobox   3 kRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                    k+++++ eq+++Le+ Fe  +++  e++ +LA+ lgL+ rq+ +WFqNrRa++k
  MDP0000423596 227 KKRRLNMEQVKTLEKNFELGNKLEPERKMQLARALGLQPRQIAIWFQNRRARWK 280
                    456899***********************************************9 PP

2HD-ZIP_I/II130.75.8e-42226318193
    HD-ZIP_I/II   1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreelke 93 
                    ekkrrl+ eqvk+LE++Fe  +kLeperK++lar+Lglqprq+a+WFqnrRAR+ktkqlEkdy+ Lkr++da+k++n++L++++++L++e+++
  MDP0000423596 226 EKKRRLNMEQVKTLEKNFELGNKLEPERKMQLARALGLQPRQIAIWFQNRRARWKTKQLEKDYDLLKRQFDAIKADNDALQSQNQKLQAEIMA 318
                    69**************************************************************************************99975 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466893.81E-19218284IPR009057Homeodomain-like
PROSITE profilePS5007117.329222282IPR001356Homeobox domain
SMARTSM003891.8E-17225286IPR001356Homeobox domain
PfamPF000465.3E-15227280IPR001356Homeobox domain
CDDcd000861.06E-16227283No hitNo description
Gene3DG3DSA:1.10.10.606.1E-19229289IPR009057Homeodomain-like
PRINTSPR000312.2E-5253262IPR000047Helix-turn-helix motif
PROSITE patternPS000270257280IPR017970Homeobox, conserved site
PRINTSPR000312.2E-5262278IPR000047Helix-turn-helix motif
PfamPF021831.3E-16282322IPR003106Leucine zipper, homeobox-associated
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009744Biological Processresponse to sucrose
GO:0048826Biological Processcotyledon morphogenesis
GO:0080022Biological Processprimary root development
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 433 aa     Download sequence    Send to blast
MAGTAIISLI SVTEYSKGIE HVIGGNENIR IASLIVFALL GFPLAMIVSL GAGPWDALFG  60
GGNIPAFVLA SFAALAGGII AARRLPILSS SLNDDVDQGF GIEGVDCGGM ITCHLVIEVV  120
VWQNRSKRVE QAIIKIGGKS LINHQAMTAN GMAFFSTNFM LQTPHDRDDH QPPTSLSPML  180
PSCTPQDFHG VASFLGKRSV SFSGIELGEE AHGEDDLSDD GSQAGEKKRR LNMEQVKTLE  240
KNFELGNKLE PERKMQLARA LGLQPRQIAI WFQNRRARWK TKQLEKDYDL LKRQFDAIKA  300
DNDALQSQNQ KLQAEIMALK NREPAESINL NKDTEGSCSN RSENNSDIKL DISRTPAIDS  360
PPSSHHHQNP TLFSSSIIRP AQLFQNTSRT EAMQCQKIDQ MVKEESLTNM FCGIDDQSAA  420
GFWPWLEQHQ FN*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1274282RRARWKTKQ
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.158260.0bud| fruit| leaf| root| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Predominantly expressed in leaves and flowers. {ECO:0000269|PubMed:16055682}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that may act in the sucrose-signaling pathway. {ECO:0000269|PubMed:11292072}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00225DAPTransfer from AT1G69780Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMap-Retrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001280955.10.0homeobox-leucine zipper protein ATHB-13-like
SwissprotQ8LC031e-119ATB13_ARATH; Homeobox-leucine zipper protein ATHB-13
TrEMBLD9ZJ080.0D9ZJ08_MALDO; HD domain class transcription factor
STRINGXP_008339924.10.0(Malus domestica)
STRINGXP_008352991.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF127133106
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G69780.11e-121HD-ZIP family protein
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Ribone PA,Capella M,Chan RL
    Functional characterization of the homeodomain leucine zipper I transcription factor AtHB13 reveals a crucial role in Arabidopsis development.
    J. Exp. Bot., 2015. 66(19): p. 5929-43
    [PMID:26136262]
  3. Wang X, et al.
    Overexpressed BRH1, a RING finger gene, alters rosette leaf shape in Arabidopsis thaliana.
    Sci China Life Sci, 2018. 61(1): p. 79-87
    [PMID:28887625]
  4. Ebrahimian-Motlagh S, et al.
    JUNGBRUNNEN1 Confers Drought Tolerance Downstream of the HD-Zip I Transcription Factor AtHB13.
    Front Plant Sci, 2017. 8: p. 2118
    [PMID:29326734]