PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MDP0000243895
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Maleae; Malus
Family HSF
Protein Properties Length: 377aa    MW: 42234.3 Da    PI: 4.632
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MDP0000243895genomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind110.41.3e-34421332102
                    HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXX CS
   HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkelleki 97 
                    Fl+k++e++ed++++ ++sws+  nsfvv+d ++f+ ++Lp+yFkhsnf+SF+RQLn+YgF+kv+ ++         weF+++ F  g+++ll++i
  MDP0000243895  42 FLTKTFEMVEDPSTDAIVSWSKARNSFVVWDYHKFSATLLPRYFKHSNFSSFIRQLNTYGFRKVDPDR---------WEFANEGFLGGQRHLLKTI 128
                    9****************************************************************999.........******************* PP

                    XXXXX CS
   HSF_DNA-bind  98 krkks 102
                    kr+++
  MDP0000243895 129 KRRRH 133
                    **975 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.2E-3738131IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004151.1E-5938131IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467854.08E-3438131IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004474.5E-3142131IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.7E-194265IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.7E-198092IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434081105IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.7E-1993105IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009644Biological Processresponse to high light intensity
GO:0010200Biological Processresponse to chitin
GO:0010286Biological Processheat acclimation
GO:0034605Biological Processcellular response to heat
GO:0034620Biological Processcellular response to unfolded protein
GO:0042542Biological Processresponse to hydrogen peroxide
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0071456Biological Processcellular response to hypoxia
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 377 aa     Download sequence    Send to blast
MDGVLVKEEE VVTCTVGSSS SSSSSFSPQP IEGLHEVGPP PFLTKTFEMV EDPSTDAIVS  60
WSKARNSFVV WDYHKFSATL LPRYFKHSNF SSFIRQLNTY GFRKVDPDRW EFANEGFLGG  120
QRHLLKTIKR RRHVSQNMQQ EAGGGACVEL GQYGVETELE RLKRDRNILM TEIVKLRQQQ  180
QNSREQVMAM EGRLLTTEKK QQQMMTFLAK ALNNPSFLQT LAEKNAKNRA LHGIGRKRRL  240
AASPSLENLQ EAPRIDVVDY SASQDLGELA TMEPDIENFF STAALDNKST SGFKDRKPSL  300
VPASTGGGNL DSVDETIWEE LWSDDLIGGN PEEEAAAVGE ESEVDVEVED LVAEPADWGE  360
DLQDLVDQMG YLIRPKP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B3e-254013127129Heat shock factor protein 1
5d5v_B3e-254013127129Heat shock factor protein 1
5d5v_D3e-254013127129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1124130LKTIKRR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mdo.27810.0bud| leaf| root
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008393630.10.0heat shock factor protein HSF30
SwissprotP411521e-139HSF30_SOLPE; Heat shock factor protein HSF30
TrEMBLA0A498HQ440.0A0A498HQ44_MALDO; Uncharacterized protein
STRINGXP_008393630.10.0(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF82253143
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G26150.11e-120heat shock transcription factor A2
Publications ? help Back to Top
  1. Scharf KD,Rose S,Thierfelder J,Nover L
    Two cDNAs for tomato heat stress transcription factors.
    Plant Physiol., 1993. 102(4): p. 1355-6
    [PMID:8278556]