PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10039580
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family MIKC_MADS
Protein Properties Length: 267aa    MW: 30124.1 Da    PI: 8.3685
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10039580genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF93.11.3e-29959151
                 S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
       SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
                 krien   rqvtfskRr+g+lKKA+ELS+LCdaevaviifs+tgkl+e+ss
  Lus10039580  9 KRIENANSRQVTFSKRRTGLLKKAHELSILCDAEVAVIIFSNTGKLFEFSS 59
                 79***********************************************96 PP

2K-box71.42.7e-2410118714100
        K-box  14 aeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkklee 100
                  +++ ++el+ L++ei +Lq++q +llG+dL+ LslkeLqqLe+qL ++l+ +++kK++ll+e++e ++ +e++++ en++Lr+++ee
  Lus10039580 101 QKQNSKELDALREEIAKLQTKQMRLLGKDLNGLSLKELQQLEHQLTDGLSCVKDKKEQLLMEHLELSRVQEQRAKLENETLRRQVEE 187
                  467789******************************************************************************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006633.011161IPR002100Transcription factor, MADS-box
SMARTSM004323.4E-43160IPR002100Transcription factor, MADS-box
CDDcd002657.18E-44277No hitNo description
SuperFamilySSF554551.83E-33277IPR002100Transcription factor, MADS-box
PRINTSPR004042.3E-30323IPR002100Transcription factor, MADS-box
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PfamPF003191.6E-261057IPR002100Transcription factor, MADS-box
PRINTSPR004042.3E-302338IPR002100Transcription factor, MADS-box
PRINTSPR004042.3E-303859IPR002100Transcription factor, MADS-box
PROSITE profilePS5129713.677101191IPR002487Transcription factor, K-box
PfamPF014861.3E-18101185IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 267 aa     Download sequence    Send to blast
MGRGKIEIKR IENANSRQVT FSKRRTGLLK KAHELSILCD AEVAVIIFSN TGKLFEFSSS  60
GMKRTLSRYH KCLDSSEPAK PEQKLDIQAQ STTPSHTFLV QKQNSKELDA LREEIAKLQT  120
KQMRLLGKDL NGLSLKELQQ LEHQLTDGLS CVKDKKEQLL MEHLELSRVQ EQRAKLENET  180
LRRQVEELRG FFPSADRSVP SYLEFQSMEQ KNSSITTNGC ISPDAAYNCS TEKGDSDTTL  240
HLGLPTNVYR KRKAPETESC STESES*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6byy_A1e-22187184MEF2 CHIMERA
6byy_B1e-22187184MEF2 CHIMERA
6byy_C1e-22187184MEF2 CHIMERA
6byy_D1e-22187184MEF2 CHIMERA
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the negative regulation of flowering, probably through the photoperiodic pathway. Acts as both an activator and a repressor of transcription. Binds DNA in a sequence-specific manner in large CArG motif 5'-CC (A/T)8 GG-3'. Participates probably in the regulation of programs active during the early stages of embryo development. Prevents premature perianth senescence and abscission, fruits development and seed desiccation. Stimulates the expression of at least DTA4, LEC2, FUS3, ABI3, AT4G38680/CSP2 and GRP2B/CSP4. Can enhance somatic embryo development in vitro. {ECO:0000269|PubMed:10318690, ECO:0000269|PubMed:10662856, ECO:0000269|PubMed:12226488, ECO:0000269|PubMed:12743119, ECO:0000269|PubMed:14615187, ECO:0000269|PubMed:15084721, ECO:0000269|PubMed:15686521, ECO:0000269|PubMed:17521410, ECO:0000269|PubMed:18305206, ECO:0000269|PubMed:19269998, ECO:0000269|PubMed:19767455, ECO:0000269|PubMed:8953767}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10039580
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin (2,4-D). Feedback loop leading to direct down-regulation by itself. {ECO:0000269|PubMed:15686521}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002534454.21e-134agamous-like MADS-box protein AGL15 isoform X1
SwissprotQ388472e-80AGL15_ARATH; Agamous-like MADS-box protein AGL15
TrEMBLA0A067L5A51e-132A0A067L5A5_JATCU; Uncharacterized protein
STRINGLus100395800.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF35823260
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G13790.11e-81AGAMOUS-like 15
Publications ? help Back to Top
  1. Zheng Q,Zheng Y,Perry SE
    Decreased GmAGL15 expression and reduced ethylene synthesis may contribute to reduced somatic embryogenesis in a poorly embryogenic cultivar of Glycine max.
    Plant Signal Behav, 2014.
    [PMID:23838957]
  2. Perry SE,Zheng Q,Zheng Y
    Transcriptome analysis indicates that GmAGAMOUS-Like 15 may enhance somatic embryogenesis by promoting a dedifferentiated state.
    Plant Signal Behav, 2016. 11(7): p. e1197463
    [PMID:27302197]
  3. Cosio C, et al.
    The class III peroxidase PRX17 is a direct target of the MADS-box transcription factor AGAMOUS-LIKE15 (AGL15) and participates in lignified tissue formation.
    New Phytol., 2017. 213(1): p. 250-263
    [PMID:27513887]
  4. Zheng Q,Zheng Y,Ji H,Burnie W,Perry SE
    Gene Regulation by the AGL15 Transcription Factor Reveals Hormone Interactions in Somatic Embryogenesis.
    Plant Physiol., 2016. 172(4): p. 2374-2387
    [PMID:27794101]
  5. Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD
    HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 600-619
    [PMID:29475938]