PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10011009
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family C2H2
Protein Properties Length: 382aa    MW: 42975.7 Da    PI: 7.1593
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10011009genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.30.001179101323
                  ET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                  C+   Cgk+F +   L++H   H
  Lus10011009  79 CSfdSCGKTFIDAGALRKHSHIH 101
                  77779**************7766 PP

2zf-C2H219.42.8e-06106130123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+C+   Cgk F ++s LkrH   H
  Lus10011009 106 YVCHfeGCGKKFIDSSKLKRHNLIH 130
                  9********************8777 PP

3zf-C2H223.21.7e-07136160123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  ++Cp  dCgk Fs   nL++H++tH
  Lus10011009 136 FVCPheDCGKAFSLDFNLRSHMKTH 160
                  89**********************9 PP

4zf-C2H214.97.9e-05166191123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  + Cp   Cgk++ + + L++Hi++ H
  Lus10011009 166 HICPfaECGKRYAHDYKLRNHIQSqH 191
                  68********************9988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.602.9E-1272103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.03777101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.03277106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576673.28E-881130No hitNo description
Gene3DG3DSA:3.30.160.601.1E-14104126IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0028106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015714.025106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576671.69E-14117170No hitNo description
Gene3DG3DSA:3.30.160.605.0E-20127161IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.069136165IPR007087Zinc finger, C2H2
SMARTSM003555.8E-4136160IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.608.6E-7162191IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.13166191IPR015880Zinc finger, C2H2-like
PROSITE profilePS501578.954166191IPR007087Zinc finger, C2H2
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.605.8E-8238269IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576678.24E-5242270No hitNo description
PROSITE profilePS501579.39245274IPR007087Zinc finger, C2H2
SMARTSM003550.92245269IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280247269IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 382 aa     Download sequence    Send to blast
METHYSHNPF DRRPIFASKA PAVKWFKEWV PQDVVATGGK CSILKWVTES QLKALKEKAK  60
EPPVPELEPE PTTEVLFLCS FDSCGKTFID AGALRKHSHI HGERQYVCHF EGCGKKFIDS  120
SKLKRHNLIH TGERNFVCPH EDCGKAFSLD FNLRSHMKTH SQENYHICPF AECGKRYAHD  180
YKLRNHIQSQ HGKSGFASNQ SPTPETVKYA TPPEKTPKAP KPPPPSASSS RPPAAPTPPS  240
LDRPYACPYH ACRKAYIHEY KLKLHLRDHP DHNIDENHHH HHNNADNGMD DENANGGGSR  300
RSRAKPSLKT PPTTKVAKRK AGSSPSPNVV AKKAAVVWPP GGNEEEDSEE TEEDRESGGE  360
DGWRYREGNE EEDDEETEYE D*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C1e-31791898116PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10011009
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019464675.11e-153PREDICTED: uncharacterized zinc finger protein At4g06634-like
SwissprotQ2V3L31e-129YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A1Q3AZP21e-156A0A1Q3AZP2_CEPFO; Zf-H2C2_2 domain-containing protein/zf-C2H2_4 domain-containing protein
STRINGLus100110090.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-106C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]