PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10005340
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family ARR-B
Protein Properties Length: 651aa    MW: 71313.8 Da    PI: 6.6587
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10005340genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like89.43.1e-28195248155
      G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                  kpr++W+ eLH++Fv+av++L G +kA+Pk+il+lm+v+ Lt+e+v+SHLQkYRl
  Lus10005340 195 KPRVVWSVELHRKFVSAVNHL-GVDKAVPKKILDLMNVEKLTRENVASHLQKYRL 248
                  79*******************.********************************8 PP

2Response_reg75.91.5e-25181261109
                   EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTES CS
  Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGak 95 
                   vl vdD+ + + +l+++l+k +y +v+++++++ al++l+e++  +Dl++ D+ mp+mdG++ll++   e  +lp+i+++a+++++ + + +  Ga 
   Lus10005340  18 VLAVDDDLTCLLVLETLLRKCQY-HVTTTSQARMALTMLRERRndFDLVISDVHMPDMDGFHLLEKVGLEM-DLPVIMLSANSDPKVVMKGITHGAC 112
                   799********************.***************888888**********************6644.8************************ PP

                   EEEESS--HHHHHH CS
  Response_reg  96 dflsKpfdpeelvk 109
                   d+l Kp+ +eel +
   Lus10005340 113 DYLLKPIRIEELKN 126
                   ***********987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.40.50.23001.3E-4215154No hitNo description
SuperFamilySSF521727.26E-3515139IPR011006CheY-like superfamily
SMARTSM004487.2E-3116128IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011042.15917132IPR001789Signal transduction response regulator, receiver domain
PfamPF000729.4E-2318126IPR001789Signal transduction response regulator, receiver domain
CDDcd001561.94E-2619131No hitNo description
Gene3DG3DSA:1.10.10.606.3E-30192253IPR009057Homeodomain-like
PROSITE profilePS5129412.093192251IPR017930Myb domain
SuperFamilySSF466891.79E-19193252IPR009057Homeodomain-like
TIGRFAMsTIGR015573.4E-25195248IPR006447Myb domain, plants
PfamPF002494.4E-7197247IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0009414Biological Processresponse to water deprivation
GO:0010082Biological Processregulation of root meristem growth
GO:0010380Biological Processregulation of chlorophyll biosynthetic process
GO:0031537Biological Processregulation of anthocyanin metabolic process
GO:0048367Biological Processshoot system development
GO:0080022Biological Processprimary root development
GO:0080036Biological Processregulation of cytokinin-activated signaling pathway
GO:0080113Biological Processregulation of seed growth
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 651 aa     Download sequence    Send to blast
MTVEQGENRD QFPIGMRVLA VDDDLTCLLV LETLLRKCQY HVTTTSQARM ALTMLRERRN  60
DFDLVISDVH MPDMDGFHLL EKVGLEMDLP VIMLSANSDP KVVMKGITHG ACDYLLKPIR  120
IEELKNIWQH VVRRKKTDNR DKNNSDNRDN KSNSQSGEAT SEQKLNKKRK DQIDEEDEDS  180
DDNGNDYDDP TSQKKPRVVW SVELHRKFVS AVNHLGVDKA VPKKILDLMN VEKLTRENVA  240
SHLQKYRLYL KRISTVANQQ ANMAAALVSS DASYLQMGPL TGLGLHNVAG NGQFQNGGFR  300
SVTPNGMLGR LNSPAGMSFH GLPSPGMMQV AHGQTGGHLA SQNQFQSVIS NANVLQGMPV  360
SLELDQIQPN KGLNYMREIP TAIESTSGFA DTSMAVGSSN GSFVGASSDK SLFPDRRRLQ  420
GTQPDAKFSK QTSLIGSSLD QGFSLDPGRC NESWTNAAPS TGVQSNSLII NDSFRTGGLP  480
ASNILRDNMS TMTMQTRSRQ CEVSPLSMLP LHLQDEKADL GCRLVSASSG GVGEIISSWD  540
NNRQASPYYF NAASSSGNSS ILDDVINQRW DANCNAMLQR NPSFGSTGQS SFIDSSLVKH  600
DGVAADASRI SNGRTLMNEH NLQTDHNNFG SLEDVATGFM VTRHPTSSNK *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A2e-27191254164ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). Involved in activating SHY2 during meristem growth and controls PIN expression via activation of SHY2 (PubMed:20605455). {ECO:0000250|UniProtKB:Q940D0, ECO:0000269|PubMed:17363254, ECO:0000269|PubMed:20605455}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10005340
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015572552.10.0two-component response regulator ARR12 isoform X1
RefseqXP_025012481.10.0two-component response regulator ARR12 isoform X2
SwissprotP625981e-136ARR12_ARATH; Two-component response regulator ARR12
TrEMBLB9RNX80.0B9RNX8_RICCO; Two-component response regulator
STRINGLus100053400.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF95634112
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G25180.11e-115response regulator 12
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Cortleven A, et al.
    A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors.
    Plant Physiol., 2014. 164(3): p. 1470-83
    [PMID:24424319]
  3. Kim HJ,Kieber JJ,Schaller GE
    The rice F-box protein KISS ME DEADLY2 functions as a negative regulator of cytokinin signalling.
    Plant Signal Behav, 2013. 8(12): p. e26434
    [PMID:24675172]
  4. Choi SH, et al.
    Gene duplication of type-B ARR transcription factors systematically extends transcriptional regulatory structures in Arabidopsis.
    Sci Rep, 2014. 4: p. 7197
    [PMID:25425016]
  5. Jiang L, et al.
    Strigolactones spatially influence lateral root development through the cytokinin signaling network.
    J. Exp. Bot., 2016. 67(1): p. 379-89
    [PMID:26519957]
  6. Cortleven A, et al.
    Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes.
    Plant Physiol., 2016. 172(1): p. 464-78
    [PMID:27388681]
  7. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  8. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  9. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  10. Kobayashi K,Iwase A
    Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal.
    Plant Signal Behav, 2017. 12(6): p. e1338999
    [PMID:28594268]
  11. Dai X, et al.
    ARR12 promotes de novo shoot regeneration in Arabidopsis thaliana via activation of WUSCHEL expression.
    J Integr Plant Biol, 2017. 59(10): p. 747-758
    [PMID:28681564]
  12. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  13. Yan Z, et al.
    Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1.
    Plant Physiol., 2017. 175(3): p. 1438-1454
    [PMID:28931628]
  14. Bustillo-AvendaƱo E, et al.
    Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis.
    Plant Physiol., 2018. 176(2): p. 1709-1727
    [PMID:29233938]