PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Lus10000585
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Linaceae; Linum
Family C2H2
Protein Properties Length: 352aa    MW: 39657.9 Da    PI: 6.9244
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Lus10000585genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.30.0005179101323
                  ET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                  C+   Cgk+F +   L++H   H
  Lus10000585  79 CSfdGCGKTFIDAGALRKHSHIH 101
                  78889**************7766 PP

2zf-C2H2232e-07106130123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  y+Cp   Cgk Fs   nL++H++tH
  Lus10000585 106 YVCPyeGCGKAFSLDFNLRSHMKTH 130
                  99**********************9 PP

3zf-C2H214.40.00011136161123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  + Cp   Cgk++ + + L++Hi++ H
  Lus10000585 136 HICPftECGKRYAHDYKLRNHIQSqH 161
                  68********************9988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576674.4E-572102No hitNo description
Gene3DG3DSA:3.30.160.608.8E-1472102IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.003277101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.78377106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576673.3E-994140No hitNo description
Gene3DG3DSA:3.30.160.601.7E-14103129IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003551.5E-4106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.882106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.9E-7130159IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.16136161IPR015880Zinc finger, C2H2-like
PROSITE profilePS501578.954136161IPR007087Zinc finger, C2H2
PROSITE patternPS000280138161IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.609.3E-8208239IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576678.53E-5212239No hitNo description
SMARTSM003550.52215239IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.39215244IPR007087Zinc finger, C2H2
PROSITE patternPS000280217239IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 352 aa     Download sequence    Send to blast
METHYSHNPF DRRPIFASKA PAVKWFKEWV PQDVVATGGK CSILKWVTES QLKALKEKAK  60
EPPAPEPEPE PTTEVLFLCS FDGCGKTFID AGALRKHSHI HGERQYVCPY EGCGKAFSLD  120
FNLRSHMKTH SQENYHICPF TECGKRYAHD YKLRNHIQSQ HEKSGFASNQ SPTPETVRYA  180
TPPEKAPKAP KPPPPSASSS RPPAAPTPPS LDRPYACPYY ACRKAYIHEY KLKLHLRDHP  240
DHNIDENHHH RHNNAENGMD DENANGGGSR RSRAKPTLKT PPTTKVAKRK AGSSPSPNVV  300
AKKKAVVWPP GVNEEEDSEE TEEDRESGGE DGWRYREGNE EEDDEETEYE D*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C7e-19792398117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLus10000585
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024454063.11e-127zinc finger transcription factor YY1 isoform X2
SwissprotQ2V3L31e-106YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A1Q3AZP21e-130A0A1Q3AZP2_CEPFO; Zf-H2C2_2 domain-containing protein/zf-C2H2_4 domain-containing protein
STRINGLus100005850.0(Linum usitatissimum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.16e-84C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]