PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID WALNUT_00002718-RA
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Juglandaceae; Juglans
Family ARR-B
Protein Properties Length: 732aa    MW: 80940 Da    PI: 7.2883
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
WALNUT_00002718-RAgenomeJHUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like59.57.3e-19220263145
             G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtleh 45 
                         kpr++W+ eLH++Fv av+qL G++kA+Pk+il+lm+v+ Lt+e+
  WALNUT_00002718-RA 220 KPRVVWSVELHRKFVAAVHQL-GIDKAVPKKILDLMNVEKLTREN 263
                         79*******************.********************987 PP

2Response_reg777e-26381461109
                         EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHH CS
        Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalea 89 
                         vl vdD+p+ + +l+++l++ +y +v+++ ++ +al+ll+e++  +Dl++ D+ mp+mdG++ll+     e++lp+i+++a+++++++ + 
  WALNUT_00002718-RA  38 VLAVDDDPTCLFVLETLLRRCQY-HVTTTNQAIKALKLLRENKnnFDLVISDVHMPDMDGFKLLELVGL-EMDLPVIMLSANDDPKLVMKG 126
                         799********************.***************888888*******************87754.558****************** PP

                         HHTTESEEEESS--HHHHHH CS
        Response_reg  90 lkaGakdflsKpfdpeelvk 109
                         +  Ga d+l Kp+  eel +
  WALNUT_00002718-RA 127 ITHGACDYLLKPVRTEELKN 146
                         *****************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363929.8E-15311694IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23001.9E-4235159No hitNo description
SuperFamilySSF521721.85E-3535156IPR011006CheY-like superfamily
SMARTSM004482.2E-3136148IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011043.2537152IPR001789Signal transduction response regulator, receiver domain
PfamPF000722.2E-2338146IPR001789Signal transduction response regulator, receiver domain
CDDcd001566.25E-2639151No hitNo description
SuperFamilySSF466891.36E-11217271IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.606.9E-20218271IPR009057Homeodomain-like
TIGRFAMsTIGR015571.2E-15220263IPR006447Myb domain, plants
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0009414Biological Processresponse to water deprivation
GO:0010082Biological Processregulation of root meristem growth
GO:0010380Biological Processregulation of chlorophyll biosynthetic process
GO:0031537Biological Processregulation of anthocyanin metabolic process
GO:0048367Biological Processshoot system development
GO:0080022Biological Processprimary root development
GO:0080036Biological Processregulation of cytokinin-activated signaling pathway
GO:0080113Biological Processregulation of seed growth
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 732 aa     Download sequence    Send to blast
MPTDGIRLQR TFTNQKQKMT VEPIMDDSRD QFPIGMRVLA VDDDPTCLFV LETLLRRCQY  60
HVTTTNQAIK ALKLLRENKN NFDLVISDVH MPDMDGFKLL ELVGLEMDLP VIMLSANDDP  120
KLVMKGITHG ACDYLLKPVR TEELKNIWQH VVRRKKFDSK DSNNSGSQDK PHPGIGGGSG  180
SAGTLSDPNG KLNKKRKDQN EDEDEEHDEN VNDDPSTQKK PRVVWSVELH RKFVAAVHQL  240
GIDKAVPKKI LDLMNVEKLT RENKYRLYLK RLNSMVNQQA NMAAALGGTD SSYLRMGSLN  300
GLENFHTLNG SGQFHNTSFR SFPPSGLLGR LNTPAGMGMR GLSSSGMTQL SHARSSSGST  360
VDQADSQQVI HPGNHNGGVL QGMPMTLELD QLQHIKGVTH VRELSTAIDN RAIFPICSGL  420
LDAKTNIGSS SNPLLGVANT TLMLEQNPRA VQGGEVFGNR SPVSLASLNS ELSSPLLDHR  480
RLNENWSTAA QSSGIHSNSF QLNDCFKQTT QSTMHQSNVR DDISKRAIQM GSNLHDVSSA  540
TSVSTELQDR RSDMQCGASL TSSNAGKINN HAGPQCWVDH NQDSSYRSNV MCSTMNSMIP  600
VQGAVGPFVQ SSDPKNFHPD MDFNSIGQSN LFDPSYTKHD EVNKSHVETS LKLKQGLRDQ  660
RKPQESYISS SFGSLEDIVT AMVKRTPAIR LKQSGYINFV DQWDVVGELS IAHQSVISSY  720
EQIYSFKSTL FS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A3e-18216273164ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). Involved in activating SHY2 during meristem growth and controls PIN expression via activation of SHY2 (PubMed:20605455). {ECO:0000250|UniProtKB:Q940D0, ECO:0000269|PubMed:17363254, ECO:0000269|PubMed:20605455}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018850232.10.0PREDICTED: two-component response regulator ARR12-like
RefseqXP_018850233.10.0PREDICTED: two-component response regulator ARR12-like
RefseqXP_018850234.10.0PREDICTED: two-component response regulator ARR12-like
SwissprotP625981e-134ARR12_ARATH; Two-component response regulator ARR12
TrEMBLA0A2I4H2810.0A0A2I4H281_JUGRE; Two-component response regulator
STRINGXP_002515447.10.0(Ricinus communis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF95634112
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G25180.11e-127response regulator 12
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Cortleven A, et al.
    A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors.
    Plant Physiol., 2014. 164(3): p. 1470-83
    [PMID:24424319]
  3. Kim HJ,Kieber JJ,Schaller GE
    The rice F-box protein KISS ME DEADLY2 functions as a negative regulator of cytokinin signalling.
    Plant Signal Behav, 2013. 8(12): p. e26434
    [PMID:24675172]
  4. Choi SH, et al.
    Gene duplication of type-B ARR transcription factors systematically extends transcriptional regulatory structures in Arabidopsis.
    Sci Rep, 2014. 4: p. 7197
    [PMID:25425016]
  5. Jiang L, et al.
    Strigolactones spatially influence lateral root development through the cytokinin signaling network.
    J. Exp. Bot., 2016. 67(1): p. 379-89
    [PMID:26519957]
  6. Cortleven A, et al.
    Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes.
    Plant Physiol., 2016. 172(1): p. 464-78
    [PMID:27388681]
  7. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  8. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  9. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  10. Kobayashi K,Iwase A
    Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal.
    Plant Signal Behav, 2017. 12(6): p. e1338999
    [PMID:28594268]
  11. Dai X, et al.
    ARR12 promotes de novo shoot regeneration in Arabidopsis thaliana via activation of WUSCHEL expression.
    J Integr Plant Biol, 2017. 59(10): p. 747-758
    [PMID:28681564]
  12. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  13. Yan Z, et al.
    Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1.
    Plant Physiol., 2017. 175(3): p. 1438-1454
    [PMID:28931628]
  14. Bustillo-AvendaƱo E, et al.
    Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis.
    Plant Physiol., 2018. 176(2): p. 1709-1727
    [PMID:29233938]