PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Itr_sc001669.1_g00011.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea
Family E2F/DP
Protein Properties Length: 343aa    MW: 38421.1 Da    PI: 5.7367
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Itr_sc001669.1_g00011.1genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP61.11.6e-1984136158
                  E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnl 58 
                              r+++sL+llt+kf++l++++e+g+++ln  a+ L   +v  ++RRiYDi+NVLe++++
  Itr_sc001669.1_g00011.1  84 RYDNSLGLLTKKFIQLIQEAEDGTLDLNRSADIL---EV--QKRRIYDITNVLEGVGI 136
                              689*******************************...99..**************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.0E-2082136IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.17E-1184136IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.5E-1984187IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.1E-1786136IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.92E-30152259No hitNo description
PfamPF164212.5E-22160257IPR032198E2F transcription factor, CC-MB domain
SuperFamilySSF1440748.63E-24160259No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 343 aa     Download sequence    Send to blast
MTRLLTSGRP AGYRTGPCTG NDDRLVGSRY QVQKTAETAN NSLLQQATFA AECRKARATK  60
RAKYGTQGIN SDPLDSLNVA GSCRYDNSLG LLTKKFIQLI QEAEDGTLDL NRSADILEVQ  120
KRRIYDITNV LEGVGIDLHR GFETTESREL QDQVYRLKVA EVEHLYTEDQ QLDYCIRKKL  180
EQLRALESDL NCQKNLFLTE DDIMSLPRFK DQTIIAVKAP YASSVKVPDP SEDGVFPEKH  240
YRLIVRSTTG PIDLYLLSKK DGQHEDVNVK HAISSDSLTG NGSRDNKMDI TMSSVSSDTS  300
TLNAKKLSQI QKIMPSHASI DDDYWLCSDK VVSATELWGR DDS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A9e-1783136660PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019156548.10.0PREDICTED: transcription factor E2FC-like
SwissprotQ9FV704e-69E2FC_ARATH; Transcription factor E2FC
TrEMBLA0A328E6R01e-156A0A328E6R0_9ASTE; Uncharacterized protein
STRINGXP_009783024.11e-118(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA126252022
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.12e-71E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]