PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Itr_sc000984.1_g00007.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Convolvulaceae; Ipomoeeae; Ipomoea
Family C2H2
Protein Properties Length: 507aa    MW: 55948.4 Da    PI: 6.1967
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Itr_sc000984.1_g00007.1genomeKazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H221.18.4e-07259280223
                              EETTTTEEESSHHHHHHHHHHT CS
                  zf-C2H2   2 kCpdCgksFsrksnLkrHirtH 23 
                               C++Cgk F+r  nL+ H+r H
  Itr_sc000984.1_g00007.1 259 FCTICGKGFKRDANLRMHMRGH 280
                              6*******************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.35E-5256283No hitNo description
PROSITE profilePS5015712.03258285IPR007087Zinc finger, C2H2
SMARTSM003550.0026258280IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.605.4E-6259309IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280260280IPR007087Zinc finger, C2H2
SMARTSM0035562307340IPR015880Zinc finger, C2H2-like
SMARTSM0035525345367IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010044Biological Processresponse to aluminum ion
GO:0010447Biological Processresponse to acidic pH
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 507 aa     Download sequence    Send to blast
MDPDNGLDSD PWTKSSLSCN DFLENVPPDD QPFNVFTLQQ QKWESSFLNQ LNQPAQNQSS  60
VSTINNIQIR VPDQQDTQAC DSNKIQEWDP KTMLNNLSFL EKKIHELQDL VHVIVGRRGQ  120
VGFQANELLV QQQQLITADL TSIIVQLIST AGSLLPTVKH TLSYAGQAAQ LVQSGGVATP  180
SGAGFNSSAL PQSVNVSKVE DHSIHIDPVG DSGMDQNCTV EEHELKDEDE AEEEENLPPG  240
SYEILQLEKE EILAPHTHFC TICGKGFKRD ANLRMHMRGH GDEYKTPAAL AKPHKEVSSV  300
PALIKRYSCP YVGCKRNREH KKFQPLKTIL CVKNHYKRTH CEKSYTCSRC NIKKFSVIAD  360
LKTHEKHCGK DKWLCSCGTT FSRKDKLFGH IALFQGHTPA IPLDDHKGSS SGLSDQGQNT  420
AGQIDPKLNN AYSGSGSGSP QNAIDVKGSV NDPGNYFSPM NYDTGDLGGF QDFPRVPFED  480
SNSSFSFLLS GSCDYPQKAG KYGSSSE
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269|PubMed:17535918, ECO:0000269|PubMed:18826429, ECO:0000269|PubMed:19321711, ECO:0000269|PubMed:23935008}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00196ampDAPTransfer from AT1G34370Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269|PubMed:17535918}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019180664.10.0PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1
RefseqXP_019180665.10.0PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1
SwissprotQ9C8N50.0STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBLA0A1Q3CHW40.0A0A1Q3CHW4_CEPFO; Zf-C2H2 domain-containing protein
STRINGXP_009620662.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA47542441
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G34370.21e-170C2H2 family protein
Publications ? help Back to Top
  1. Kobayashi Y, et al.
    Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions.
    Plant Physiol., 2013. 163(1): p. 180-92
    [PMID:23839867]
  2. Yokosho K,Yamaji N,Ma JF
    Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench).
    Plant Cell Physiol., 2014. 55(12): p. 2077-91
    [PMID:25273892]
  3. Geng X, et al.
    LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.
    Plant J., 2017. 90(3): p. 491-504
    [PMID:28181322]
  4. Balzergue C, et al.
    Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation.
    Nat Commun, 2017. 8: p. 15300
    [PMID:28504266]
  5. Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A
    Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation.
    Front Plant Sci, 2017. 8: p. 822
    [PMID:28567051]
  6. Jiang F, et al.
    Identification and characterization of suppressor mutants of stop1.
    BMC Plant Biol., 2017. 17(1): p. 128
    [PMID:28738784]
  7. Daspute AA, et al.
    Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
    Front Plant Sci, 2017. 8: p. 1358
    [PMID:28848571]
  8. Sharma A,Wai CM,Ming R,Yu Q
    Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis.
    Genome Biol Evol, 2017. 9(9): p. 2170-2190
    [PMID:28922793]
  9. Zhang Y, et al.
    The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 118
    [PMID:29491872]