PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G002770.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family AP2
Protein Properties Length: 451aa    MW: 50400.8 Da    PI: 4.6814
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G002770.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP249.88.2e-1672122155
                   AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                           + y+GVr++  + +Wv+e+r+p++   ++r++lg++ t e+Aa+a++ a+ +++g
  HL.SW.v1.0.G002770.1  72 PVYRGVRRRN-NDKWVCELREPNT---KTRIWLGTYPTLEMAARAHDVAAIAFRG 122
                           68*****887.8*********833...5***********************9998 PP

2AP249.88.2e-16270320155
                   AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                           + y+GVr++  + +Wv+e+r+p++   ++r++lg++ t e+Aa+a++ a+ +++g
  HL.SW.v1.0.G002770.1 270 PVYRGVRRRN-NDKWVCELREPNT---KTRIWLGTYPTLEMAARAHDVAAIAFRG 320
                           68*****887.8*********833...5***********************9998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008474.6E-1272122IPR001471AP2/ERF domain
SuperFamilySSF541713.86E-2073132IPR016177DNA-binding domain
SMARTSM003801.6E-2673136IPR001471AP2/ERF domain
PROSITE profilePS5103221.4773130IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.0E-2973132IPR001471AP2/ERF domain
PRINTSPR003671.4E-67485IPR001471AP2/ERF domain
CDDcd000187.11E-2874132No hitNo description
PRINTSPR003671.4E-696112IPR001471AP2/ERF domain
PfamPF008474.6E-12270320IPR001471AP2/ERF domain
SMARTSM003801.6E-26271334IPR001471AP2/ERF domain
SuperFamilySSF541713.86E-20271330IPR016177DNA-binding domain
PROSITE profilePS5103221.47271328IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.0E-29271330IPR001471AP2/ERF domain
CDDcd000187.11E-28272330No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 451 aa     Download sequence    Send to blast
MDYFSQLTDT CHYVVESSIS DNNINYKEGS SSPFSSEEAS RGASHSDEEV ILASNRPKKR  60
AGRRVFKETR HPVYRGVRRR NNDKWVCELR EPNTKTRIWL GTYPTLEMAA RAHDVAAIAF  120
RGKSACLNFA DSAWLLPRPV SLDAKDIRAA AREGAEAFRP AEYGGVSEEK QNENESVVVM  180
NESTEKNESV FFMDDDATLD MPGFLADLAE GLLLPPPYNY FSADDEGSSS PFSSEEASRG  240
ASHSDEEVIL ASNRPKKRAG RRVFKETRHP VYRGVRRRNN DKWVCELREP NTKTRIWLGT  300
YPTLEMAARA HDVAAIAFRG KSACLNFADS AWLLPRPVSL DAKDIRAAAR EGAEAFRPAE  360
YGGVSEEKQN ENESVVVVDE STEKNESVVV VVVDESTEKN ESVFFMDDDA TLDMPGFLAD  420
LAEGLLLPPP YNYFSTDDVE RNDDVSLWSY *
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates abscisic acid- and dehydration-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation. {ECO:0000269|PubMed:11798174, ECO:0000269|PubMed:12376631}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By high-salt stress, drought stress and abscisic acid (ABA) treatment. {ECO:0000269|PubMed:11798174, ECO:0000269|PubMed:12376631}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015867318.14e-86dehydration-responsive element-binding protein 1A-like
RefseqXP_015901870.14e-86dehydration-responsive element-binding protein 1A-like
SwissprotQ9FJ931e-64DRE1D_ARATH; Dehydration-responsive element-binding protein 1D
TrEMBLA0A3Q7FF311e-133A0A3Q7FF31_SOLLC; Uncharacterized protein
STRINGXP_004298771.11e-83(Fragaria vesca)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF24333224
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G51990.18e-61C-repeat-binding factor 4
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Guttikonda SK, et al.
    Overexpression of AtDREB1D transcription factor improves drought tolerance in soybean.
    Mol. Biol. Rep., 2014. 41(12): p. 7995-8008
    [PMID:25192890]
  3. Zhang T, et al.
    Overexpression of a NF-YB3 transcription factor from Picea wilsonii confers tolerance to salinity and drought stress in transformed Arabidopsis thaliana.
    Plant Physiol. Biochem., 2015. 94: p. 153-64
    [PMID:26093308]
  4. Carlow CE, et al.
    Nuclear localization and transactivation by Vitis CBF transcription factors are regulated by combinations of conserved amino acid domains.
    Plant Physiol. Biochem., 2017. 118: p. 306-319
    [PMID:28675818]
  5. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]