PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.17G227600.1.p
Common NameGLYMA_17G227600, LOC100820298
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family HSF
Protein Properties Length: 356aa    MW: 40318.5 Da    PI: 4.8401
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.17G227600.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind111.94.5e-35451362102
                          HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXX CS
         HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkk 91 
                          Fl+k+++++ed+++++++sws   nsfvv+d+++f+ ++Lp+yFkh nf+SF+RQLn+YgF+kv+ ++         weF+++ F +g++
  Glyma.17G227600.1.p  45 FLSKIFDMVEDPSTDSIVSWSMARNSFVVWDSHKFSAHILPRYFKHANFSSFIRQLNTYGFRKVDPDK---------WEFANEGFLAGQR 125
                          9********************999*****************************************999.........************* PP

                          XXXXXXXXXXX CS
         HSF_DNA-bind  92 ellekikrkks 102
                          +ll++ikr+++
  Glyma.17G227600.1.p 126 HLLKTIKRRRN 136
                          ********987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.5E-3738129IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467857.89E-3341134IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004152.4E-5841134IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004478.5E-3145134IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.2E-184568IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.2E-188395IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434084108IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000562.2E-1896108IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009644Biological Processresponse to high light intensity
GO:0010200Biological Processresponse to chitin
GO:0010286Biological Processheat acclimation
GO:0034605Biological Processcellular response to heat
GO:0034620Biological Processcellular response to unfolded protein
GO:0042542Biological Processresponse to hydrogen peroxide
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0071456Biological Processcellular response to hypoxia
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 356 aa     Download sequence    Send to blast
MCMERIRVKE EEAMTCGGGG SSSSSFISPQ AQPMEGLHEV GPPPFLSKIF DMVEDPSTDS  60
IVSWSMARNS FVVWDSHKFS AHILPRYFKH ANFSSFIRQL NTYGFRKVDP DKWEFANEGF  120
LAGQRHLLKT IKRRRNVSHS NQQKGGSGAC VEVGKFGLEG ELERLKRDRN ILMAEIVRLR  180
HQQLNSRDQL SAMEARMQAT EKKQQQMMSF LAKALSNPSF MQQLVHKTPQ SREVLLGVEI  240
NRKRRLPACP SVENLQQDNQ DLATMETDMD TFFAPAYDNE FGNEIDEPAS ILVEDSILED  300
FLNKDLITGN PEDEVIIGDC TQVDVPMEDL VANPDDWSEQ LQDLVDHMDY LGSKP*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5d5u_B1e-244313427129Heat shock factor protein 1
5d5v_B1e-244313427129Heat shock factor protein 1
5d5v_D1e-244313427129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1127133LKTIKRR
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress responses. Seems to be involved in other environmental stress responses. Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs). {ECO:0000269|PubMed:16649111, ECO:0000269|PubMed:17059409, ECO:0000269|PubMed:17085506}.
Function -- GeneRIF ? help Back to Top
  1. Overexpression of the GmHsf-34 gene improved the tolerance to drought and heat stresses in Arabidopsis plants.[GmHsf-34]
    [PMID: 25416131]
Cis-element ? help Back to Top
SourceLink
PlantRegMapGlyma.17G227600.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat stress, high light and hydrogen peroxide (H(2)O(2)). {ECO:0000269|PubMed:16649111, ECO:0000269|PubMed:17059409, ECO:0000269|PubMed:17085506}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKT0311610.0KT031161.1 Glycine max clone HN_CCL_33 heat shock transcription factor (Glyma14g11030.1) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003550266.10.0heat stress transcription factor A-2
RefseqXP_028208840.10.0heat stress transcription factor A-2-like
SwissprotO809821e-125HSFA2_ARATH; Heat stress transcription factor A-2
TrEMBLA0A445GAM40.0A0A445GAM4_GLYSO; Heat stress transcription factor A-2
TrEMBLK7MNF60.0K7MNF6_SOYBN; Uncharacterized protein
STRINGGLYMA17G34540.30.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF82253143
Representative plantOGRP9617233
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G26150.11e-127heat shock transcription factor A2
Publications ? help Back to Top
  1. Liu HC,Charng YY
    Common and distinct functions of Arabidopsis class A1 and A2 heat shock factors in diverse abiotic stress responses and development.
    Plant Physiol., 2013. 163(1): p. 276-90
    [PMID:23832625]
  2. Jung HS, et al.
    Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9
    [PMID:23918368]
  3. Chauhan H,Khurana N,Agarwal P,Khurana JP,Khurana P
    A seed preferential heat shock transcription factor from wheat provides abiotic stress tolerance and yield enhancement in transgenic Arabidopsis under heat stress environment.
    PLoS ONE, 2013. 8(11): p. e79577
    [PMID:24265778]
  4. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  5. Weng M, et al.
    Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana.
    Plant Cell Environ., 2014. 37(9): p. 2128-38
    [PMID:24548003]
  6. Jang YH, et al.
    A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana.
    Plant J., 2014. 78(4): p. 591-603
    [PMID:24580679]
  7. Stief A, et al.
    Arabidopsis miR156 Regulates Tolerance to Recurring Environmental Stress through SPL Transcription Factors.
    Plant Cell, 2014. 26(4): p. 1792-1807
    [PMID:24769482]
  8. Li PS, et al.
    Genome-wide analysis of the Hsf family in soybean and functional identification of GmHsf-34 involvement in drought and heat stresses.
    BMC Genomics, 2014. 15: p. 1009
    [PMID:25416131]
  9. Dobrá J, et al.
    The impact of heat stress targeting on the hormonal and transcriptomic response in Arabidopsis.
    Plant Sci., 2015. 231: p. 52-61
    [PMID:25575991]
  10. Yamauchi Y,Kunishima M,Mizutani M,Sugimoto Y
    Reactive short-chain leaf volatiles act as powerful inducers of abiotic stress-related gene expression.
    Sci Rep, 2015. 5: p. 8030
    [PMID:25619826]
  11. Shi H, et al.
    Melatonin induces class A1 heat-shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis.
    J. Pineal Res., 2015. 58(3): p. 335-42
    [PMID:25711624]
  12. Mueller SP,Krause DM,Mueller MJ,Fekete A
    Accumulation of extra-chloroplastic triacylglycerols in Arabidopsis seedlings during heat acclimation.
    J. Exp. Bot., 2015. 66(15): p. 4517-26
    [PMID:25977236]
  13. Nie S,Yue H,Xing D
    A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance.
    Plant Physiol., 2016.
    [PMID:26099269]
  14. Nguyen AH, et al.
    Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress.
    Plant Cell Physiol., 2015. 56(9): p. 1762-72
    [PMID:26136597]
  15. Hu Z, et al.
    Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis.
    Plant J., 2015. 84(6): p. 1178-91
    [PMID:26576681]
  16. Lämke J,Brzezinka K,Bäurle I
    HSFA2 orchestrates transcriptional dynamics after heat stress in Arabidopsis thaliana.
    Transcription, 2016. 7(4): p. 111-4
    [PMID:27383578]
  17. Wang X,Huang W,Liu J,Yang Z,Huang B
    Molecular regulation and physiological functions of a novel FaHsfA2c cloned from tall fescue conferring plant tolerance to heat stress.
    Plant Biotechnol. J., 2017. 15(2): p. 237-248
    [PMID:27500592]
  18. Chen ST,He NY,Chen JH,Guo FQ
    Identification of core subunits of photosystem II as action sites of HSP21, which is activated by the GUN5-mediated retrograde pathway in Arabidopsis.
    Plant J., 2017. 89(6): p. 1106-1118
    [PMID:27943531]
  19. Kataoka R,Takahashi M,Suzuki N
    Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis.
    Plant Signal Behav, 2017. 12(11): p. e1376159
    [PMID:28873003]
  20. Wang X,Zhuang L,Shi Y,Huang B
    Up-Regulation of HSFA2c and HSPs by ABA Contributing to Improved Heat Tolerance in Tall Fescue and Arabidopsis.
    Int J Mol Sci, 2018.
    [PMID:28914758]
  21. Llamas E,Pulido P,Rodriguez-Concepcion M
    Interference with plastome gene expression and Clp protease activity in Arabidopsis triggers a chloroplast unfolded protein response to restore protein homeostasis.
    PLoS Genet., 2017. 13(9): p. e1007022
    [PMID:28937985]
  22. Li X, et al.
    Plastid Translation Elongation Factor Tu Is Prone to Heat-Induced Aggregation Despite Its Critical Role in Plant Heat Tolerance.
    Plant Physiol., 2018. 176(4): p. 3027-3045
    [PMID:29444814]