PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.10G078200.1.p
Common NameGLYMA_10G078200, LOC100809283
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family E2F/DP
Protein Properties Length: 467aa    MW: 50981.3 Da    PI: 4.9985
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.10G078200.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP832.5e-26148213171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                          r+++sL+llt+kf++l++++e gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Glyma.10G078200.1.p 148 RYDSSLGLLTKKFINLVKHAEGGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 213
                          6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.6E-28145215IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467856.89E-17148211IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.9E-34148213IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.0E-24150213IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.22E-47226330No hitNo description
SuperFamilySSF1440741.78E-32226330No hitNo description
PfamPF164212.4E-33229328IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 467 aa     Download sequence    Send to blast
MSSAAGAPDR RASPPRVAAG APTRPPLKRH LAFITKPPFA PPDEYHSFSS IGSRRAADEA  60
VVVRSPYIMK RKSGMNDSEG ESLAQKWSNS PGYTNVSNVT NNSPFKTPVS AKGGRTQKAK  120
ASKGRSCPPT PISNAGSPSP LTPASSCRYD SSLGLLTKKF INLVKHAEGG ILDLNKAAET  180
LEVQKRRIYD ITNVLEGIGL IEKKLKNRIH WKGIESATSG DVDGDISLLK AEVEKLSLEE  240
QGIDDQIREM QERLRNLSEN ENNQKCLFVT EEDIKDLPCF QNETLIAIKA PHGTTLEVPD  300
PEEAVDYPQR RYRIILRSTM GPIDVYLISQ FEEKFEEVNG AELPMIPLAS SSGSNEQLMT  360
EIVTAECSGK ELEPQTQLSS HAFSDASQEF AGGMMKIVPS DVDNDADYWL LSDADISITD  420
MWRTDSSVDW NGVDMLHPDF GVISRPQTPS SGFAEVPSTA ANSIQK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A5e-24143214274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Gma.423770.0somatic embryo
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}.
UniprotTISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGlyma.10G078200.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0930461e-107BT093046.1 Soybean clone JCVI-FLGm-15I8 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006588860.10.0transcription factor E2FA
SwissprotQ9FNY01e-159E2FA_ARATH; Transcription factor E2FA
TrEMBLI1L9I40.0I1L9I4_SOYBN; Uncharacterized protein
STRINGGLYMA10G09410.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Representative plantOGRP12251749
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-153E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]