PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.02G198700.1.p
Common NameGLYMA_02G198700, LOC100811762
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family E2F/DP
Protein Properties Length: 469aa    MW: 51113.3 Da    PI: 4.7737
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.02G198700.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.86.6e-27148213171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                          r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Glyma.02G198700.1.p 148 RYDSSLGLLTKKFINLVKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 213
                          6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.105.7E-29145215IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.2E-34148213IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.67E-17148211IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.7E-24150213IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440747.32E-33226330No hitNo description
CDDcd146601.49E-48226330No hitNo description
PfamPF164218.8E-34229328IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 469 aa     Download sequence    Send to blast
MSSAAGVPDR LASQPRGAAG APALPPLKRH LAFVTKPPFA PPDEYHSFSS ADSRRAADEA  60
VVVRSPYMKR KSGMTDSEGE SQAQKWSNSP GYTNVSNVTN NSPFKTPVSA KGGRAQKAKA  120
SKEGRSCPPT PMSNAGSPSP LTPASSCRYD SSLGLLTKKF INLVKHAEDG ILDLNKAAET  180
LEVQKRRIYD ITNVLEGIGL IEKKLKNRIH WKGIESSTSG EVDGDISVLK AEVEKLSLEE  240
QGLDDQIREM QERLRNLSEN ENNQKCLFVT EEDIKGLPCF QNETLIAIKA PHGTTLEVPD  300
PEEAVDYPQR RYRIILRSTM GPIDVYLISQ FEEKFEEVNG AELPMIPLAS SSGSNEQLMT  360
EMVPAECSGK ELEPQTQLSS HAFSDLNASQ EFAGGMMKIV PSDVDNDADY WLLSDADVSI  420
TDMWRTDSTV DWNGIDMLHP DFGIISRPQS PSSGLAEVPS TGANSIQK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A4e-25143214274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}.
UniprotTISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGlyma.02G198700.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0930461e-147BT093046.1 Soybean clone JCVI-FLGm-15I8 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006575291.10.0transcription factor E2FA
RefseqXP_028211267.10.0transcription factor E2FA-like
SwissprotQ9FNY01e-162E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A445LRK30.0A0A445LRK3_GLYSO; Transcription factor E2FA
TrEMBLI1JGJ70.0I1JGJ7_SOYBN; Uncharacterized protein
STRINGGLYMA02G35850.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Representative plantOGRP12251749
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-147E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]