PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID EPS61970.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea
Family E2F/DP
Protein Properties Length: 437aa    MW: 47523.1 Da    PI: 5.0803
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
EPS61970.1genomeLSMUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.82.8e-26150215171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                 r+++sL llt+kf++l++++e+g+++ln +a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  EPS61970.1 150 RYDSSLSLLTKKFISLIKQVEDGELDLNLAAETL---QV--QKRRIYDITNVLEGIGLIEKKLKNKIQWKG 215
                 6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.2E-27147217IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.1E-31150215IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.99E-16150213IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.7E-23152215IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440743.66E-29229329No hitNo description
PfamPF164218.7E-30231329IPR032198E2F transcription factor, CC-MB domain
CDDcd146601.21E-41231329No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 437 aa     Download sequence    Send to blast
GNGPSTTPPA APSNGQILRQ QQTPPAGIRR HLTFASMKPP FLNPDDYHRF STPAAAAASS  60
ATAADHLSEA IVVKSPRKNV HRNKAVKPSE STASPGSTNT SNPTLNTPVS CKGGRANGRS  120
KVSNSVKSSP STPISAANAL SPQTPASSCR YDSSLSLLTK KFISLIKQVE DGELDLNLAA  180
ETLQVQKRRI YDITNVLEGI GLIEKKLKNK IQWKGLDPSG PGEVANDATL LQAEIENLSM  240
EEQSLDERIR HMQEKLQILS EDENKKRWLF VNEDDIKSLP CFKNETLIAI KAPHGTTLEV  300
PDPDEAADYP QRRYRIILRS TIGRIDVYLT INYIPPTCSG SNGLPGGDSF SSHAEAQGGQ  360
VATWEGPPTT SSSQEYNPGG MTKIVPTDVD NDTDYWLSTD ADISITDMWK MDDGMPWNDE  420
TILQELQMAT IATPTDD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A7e-26145218276PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011094221.10.0transcription factor E2FA
SwissprotQ9FNY01e-126E2FA_ARATH; Transcription factor E2FA
TrEMBLS8C5A00.0S8C5A0_9LAMI; Uncharacterized protein (Fragment)
STRINGMigut.J00719.1.p1e-180(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10772484
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-118E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]
  2. Leushkin EV, et al.
    The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences.
    BMC Genomics, 2013. 14: p. 476
    [PMID:23855885]