PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462921630
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family bHLH
Protein Properties Length: 1439aa    MW: 161043 Da    PI: 6.0315
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462921630genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.59.8e-13294341355
                HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
        HLH   3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                ++h + ErrRR+++N+ ++ L++l+P+       +++Ka+iL +++ Y+k+L+
  462921630 294 KNHVMSERRRREKLNEMYAVLKSLVPTT-----HRMDKASILAETITYLKELE 341
                5799***********************7.....59***************996 PP

2HLH39.59.9e-1312561306355
                 HHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
        HLH    3 rahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55  
                 ++h + ErrRR+++N+ f  L++l+P+     +   ++Ka+iL +++ Y+k+L+
  462921630 1256 KNHVMSERRRREKLNEMFLVLKSLVPTiH---KVISMDKASILAETIAYLKELE 1306
                 5799***********************66...6666***************996 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.1E-4819189IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.139291340IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474594.45E-17294354IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.95E-14294345No hitNo description
PfamPF000102.8E-10295341IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.8E-17295353IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003535.6E-16297346IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF142155.6E-52465648IPR025610Transcription factor MYC/MYB N-terminal
SMARTSM0035316751792IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.106.8E-4770797IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF142154.5E-459151094IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088815.7912531305IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.36E-1612551319IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.07E-1412561310No hitNo description
PfamPF000103.5E-1012571306IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.7E-1612571318IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.3E-1512591311IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 1439 aa     Download sequence    Send to blast
MAPSAPPVVQ EEPPPGKQLR NQLAAAVRSI NWTYAIFWSI SNSHPRVLTW KDGFYHGEVK  60
TRRIANSMEL TVDQLVLQRS EQLRELYESL LSGTCDHRAE RPSISLSPED LGDMEWYYVV  120
CMTYAFRPGQ GLPGRSFARN EHVWLCNAHM ADSKTFPRKL LAKTASIQTI VCIPLMGGVL  180
ELGTTASITA VVDDFYGLWE ELLDVHTLHD TNLIMDGSSL VAASEAKDAA TSSIPEDSSR  240
VTHFINWTRS ESDELVVPVI EEPQKLLKKV VAAGAWMNNS VESTARTTHE RGIKNHVMSE  300
RRRREKLNEM YAVLKSLVPT THRMDKASIL AETITYLKEL EQKVKELESR RESISSPDDK  360
RPTSHENEII GKRVPATTKR KKLASKPGNG MEMEHHWVFS KDGPINVNVT VIGTESPLGL  420
FKGWPKQSQC HRHWHGGAPR GKITAMALPA ASSRLQEEPQ QGKQLTNQLA AAVRSINWSY  480
ALFWSVSSTH PGVLTWTDGF YNGEIKTRKI SNSAELTADE LVMQRSEQLR ELYRSLLSGE  540
CDHRAARPVA ALSPDELGET EWYYVVCMTY AFRPGQGLPG KSFASNEHVW LCNAHLADSK  600
TFPRVLLAKS ASIQTIVCIP LMSGVLELGT TDSVTEDPDL VSRVTTSFWD RQFRTISVDP  660
SSSCPSANVT SEDDDRIVFE DLDHNAMETM IAGANELGHV EILSNASLEH ATKGIDEFYS  720
LCEELDVQPL EDDWIMDGSF EIPCSPAAAV PGAATNDAGN RLHSELLLEV DKASILAETI  780
AYLKELERRV EELESTSREP ITQPSGTERL RGRGHVNGII GKRVCGAKRK AMDTEHQLHH  840
WVPSKDGSSN VTVTVTDRDV LLEVQCRWEE LLIARVFDAM KTLHLDVLSV QASTPDGFMG  900
LKIRAQEEQH PDMHLRSQLA AAVRSINWSY AIFWSISSSH PRALTWKDGF YNGEIKTRKI  960
ANSMELTAEQ LILQRSEQLL ELYESLLSGR CDHRTGRPVA ALSPEDLGST EWYYVVCMTY  1020
AFRPGQGLPG RCFASNEHVW LCNAHLADSK KDFPRALLAK TIVCIPLKGG VLELGTTALV  1080
PEDPDLLTRA ITYFKELKLP RGAENPSTNH VEATNVIVLD DMDEDAMETT IDEGHEIGEV  1140
DCLFSGNLEQ ITKEIDDFYG LLEEVDVQPL QDSDWIMDSL LAGPEANKDD ATLNTRGDSS  1200
RATSFTPWTR FKSDELAVRV IREPQKFLKR VVAGGAWTNN NGGESTARTP QESGIKNHVM  1260
SERRRREKLN EMFLVLKSLV PTIHKVISMD KASILAETIA YLKELERRVK ELEFRREATS  1320
RPGETRHGNF PARAKRKKVS ELSSGDMEMK HHWVLSKDRP NNVNVTVMGT EVLLEMQCRW  1380
KELLMTRVFD KIKSLSLDVL SVEASTKDCL MGLKIRAQFS SSAAISPAMI REALLFGEL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rqw_A7e-201910941192Transcription factor MYC3
4rqw_B7e-201910941192Transcription factor MYC3
4rs9_A7e-201910941192Transcription factor MYC3
4yz6_A7e-201910941192Transcription factor MYC3
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
112611266ERRRRE
212621267RRRREK
Functional Description ? help Back to Top
Source Description
UniProtPutative transcriptional activator. Control tissue-specific synthesis of anthocyanin pigments in various parts of the maize plant.
Cis-element ? help Back to Top
SourceLink
PlantRegMap462921630
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025823475.10.0anthocyanin regulatory R-S protein-like isoform X2
SwissprotP135261e-170ARLC_MAIZE; Anthocyanin regulatory Lc protein
TrEMBLK3XG260.0K3XG26_SETIT; Uncharacterized protein
STRINGSi000845m0.0(Setaria italica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP93233109
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G63650.31e-61bHLH family protein
Publications ? help Back to Top
  1. Pattanaik S,Xie CH,Yuan L
    The interaction domains of the plant Myc-like bHLH transcription factors can regulate the transactivation strength.
    Planta, 2008. 227(3): p. 707-15
    [PMID:18075757]
  2. Huang ZA, et al.
    The upregulation of NtAN2 expression at low temperature is required for anthocyanin accumulation in juvenile leaves of Lc-transgenic tobacco (Nicotiana tabacum L.).
    J Genet Genomics, 2012. 39(3): p. 149-56
    [PMID:22464474]
  3. Ludwig SR,Habera LF,Dellaporta SL,Wessler SR
    Lc, a member of the maize R gene family responsible for tissue-specific anthocyanin production, encodes a protein similar to transcriptional activators and contains the myc-homology region.
    Proc. Natl. Acad. Sci. U.S.A., 1989. 86(18): p. 7092-6
    [PMID:2674946]
  4. Li P, et al.
    Combined bulked segregant sequencing and traditional linkage analysis for identification of candidate gene for purple leaf sheath in maize.
    PLoS ONE, 2018. 13(1): p. e0190670
    [PMID:29304111]