PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10021032m
Common NameEUTSA_v10021032mg
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family E2F/DP
Protein Properties Length: 354aa    MW: 40175.2 Da    PI: 8.7511
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10021032mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.16.2e-231984171
          E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                     rkeksL++l ++fl+l+++ +++ + l+++a +L    v  +rRRiYD++N+Le+++++++k kn+++wkg
  Thhalv10021032m 19 RKEKSLGVLVSNFLRLYNRDDDDLIGLDDAAGKL---GV--ERRRIYDVVNILESIGVVARKGKNKYSWKG 84
                     79********************************...**..****************************98 PP

2E2F_TDP82.92.6e-26140220171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                      +keksL+ll+q+f+k++ +s+++ +tl+++ak L+s+     ++++k+RR+YDi+NV+++++liek     ++k++++w g
  Thhalv10021032m 140 KKEKSLWLLSQNFVKMFLCSRDDLITLDSAAKVLLSDsqdpmHMRTKVRRLYDIANVFSSMDLIEKthipgTRKPAYKWLG 220
                      69*****************************************************************************87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.6E-241685IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467858.0E-161882IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.5E-261984IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.4E-192084IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.105.7E-22136222IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.9E-30140220IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.6E-19141220IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467858.52E-13142221IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 354 aa     Download sequence    Send to blast
MSSSVAEDVD SLGLQSYSRK EKSLGVLVSN FLRLYNRDDD DLIGLDDAAG KLGVERRRIY  60
DVVNILESIG VVARKGKNKY SWKGFGEVPR SLDELKDEGM RERSGISSVS NSDKVSNDDE  120
REESFSLTPD ESSLSKMDHK KEKSLWLLSQ NFVKMFLCSR DDLITLDSAA KVLLSDSQDP  180
MHMRTKVRRL YDIANVFSSM DLIEKTHIPG TRKPAYKWLG SKSIIEKGSS FFKSSEPKKR  240
VFGRDLTNLN LTTKRNKTDC SSNHKQIGYK KYDEEDTEQE TKPAAKSYVF GPFSPTCASK  300
SKSNVGTNNN LRLQDLEALA STYRPQYCNQ ELNDLFGHYK EAWKAWYAEL DRK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-35182123228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10021032m
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006408490.10.0E2F transcription factor-like E2FF
SwissprotQ8RWL00.0E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLV4MBU30.0V4MBU3_EUTSA; Uncharacterized protein
STRINGXP_006408490.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.11e-168DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]