PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Thhalv10006369m
Common NameEUTSA_v10006369mg
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema
Family C2H2
Protein Properties Length: 258aa    MW: 28577.8 Da    PI: 6.6478
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Thhalv10006369mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H215.45.4e-0595117123
                      EEETTTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                      ++C++C + F+++  L  H++ H
  Thhalv10006369m  95 FECHYCFRNFPTSQALGGHQNAH 117
                      89******************988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576679.03E-691122No hitNo description
PfamPF139122.0E-594119IPR007087Zinc finger, C2H2
PROSITE profilePS5015710.9995122IPR007087Zinc finger, C2H2
PROSITE patternPS00028097117IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009739Biological Processresponse to gibberellin
GO:0010091Biological Processtrichome branching
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 258 aa     Download sequence    Send to blast
MDEASGEAET QDFMNVESFS QLPFFRRPPS KDKNPKPIRL FGKDFTGGNY SATTGQEDYS  60
DSSETKNKEE EEEYEEDETG DNGKDKSINN NNRRFECHYC FRNFPTSQAL GGHQNAHKRE  120
RQLAKRGASS YFHHPGANLY GYRHYPSWNS GSLPAARLYG GHTSGPSSSY YTRQVNGSTL  180
GHWCEPPSSS SVQGVYNSNA AFTSHDSSNN STLPFMAGSQ PHPPVQVGGT AVQNRMSSYR  240
YGLGPNVQDH VSLDLHL*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin (GA) (PubMed:16679458, PubMed:17507408). Mediates the induction of GL1 expression by GA in inflorescence organs and is antagonized in its action by the DELLA repressor GAI. Acts upstream of the trichome initiation regulators GL1 and GL3, and downstream of the GA signaling repressor SPINDLY (SPY) (PubMed:16679458). Does not play a significant role in the cytokinin response (PubMed:17507408). Controls trichome branching through GA signaling (PubMed:22210898, PubMed:23825141). Acts downstream of the key regulator STICHEL (STI) in an endoreduplication-independent pathway (PubMed:22210898). Controls trichome cell division indirectly by acting downstream of a key endoreduplication regulator SIAMESE (SIM) (PubMed:23825141). {ECO:0000269|PubMed:16679458, ECO:0000269|PubMed:17507408, ECO:0000269|PubMed:22210898, ECO:0000269|PubMed:23825141}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapThhalv10006369m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By gibberellin. {ECO:0000269|PubMed:16679458}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006402811.10.0zinc finger protein GIS
SwissprotQ84WI01e-118GIS_ARATH; Zinc finger protein GIS
TrEMBLV4LKJ80.0V4LKJ8_EUTSA; Uncharacterized protein
STRINGXP_006402811.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM24951949
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G58070.11e-111C2H2 family protein
Publications ? help Back to Top
  1. Sun L, et al.
    GLABROUS INFLORESCENCE STEMS3 (GIS3) regulates trichome initiation and development in Arabidopsis.
    New Phytol., 2015. 206(1): p. 220-30
    [PMID:25640859]
  2. Yu D, et al.
    RPN1a, a subunit of the 26S proteasome, controls trichome development in Arabidopsis.
    Plant Physiol. Biochem., 2015. 88: p. 82-8
    [PMID:25676129]
  3. Liu Y, et al.
    AtGIS, a C2H2 zinc-finger transcription factor from Arabidopsis regulates glandular trichome development through GA signaling in tobacco.
    Biochem. Biophys. Res. Commun., 2017. 483(1): p. 209-215
    [PMID:28034756]
  4. Vadde BVL,Challa KR,Nath U
    The TCP4 transcription factor regulates trichome cell differentiation by directly activating GLABROUS INFLORESCENCE STEMS in Arabidopsis thaliana.
    Plant J., 2018. 93(2): p. 259-269
    [PMID:29165850]
  5. Kim SY,Hyoung S,So WM,Shin JS
    The novel transcription factor TRP interacts with ZFP5, a trichome initiation-related transcription factor, and negatively regulates trichome initiation through gibberellic acid signaling.
    Plant Mol. Biol., 2018. 96(3): p. 315-326
    [PMID:29335898]