PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Do007494.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Dichantheliinae; Dichanthelium
Family GRAS
Protein Properties Length: 611aa    MW: 64774.7 Da    PI: 6.334
Description GRAS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Do007494.1genomeDichanView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1GRAS384.51.3e-1172165852374
        GRAS   2 velLlecAeavssgdlelaqalLarlselaspdg.dpmqRlaayfteALaarlarsvselykalppsetsekn.sseelaalklfsevsPilkfshlta 98 
                 v +L++cA+ ++++++ +a+ +Larl e+asp g +pm+R+aayf+eALa r++r+++++++  pp+e ++    ++ ++al++++ ++Pi++f h+t 
  Do007494.1 216 VVALTACADSLAARNHDAANYYLARLGEMASPVGpTPMHRVAAYFAEALALRVVRTWPNVFDVTPPRELTDGAvGDDDATALRILNAITPIPRFLHFTL 314
                 5689****************************************************************9988878999********************* PP

        GRAS  99 NqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesgskeeleetgerLakfAeelgvpfefnvlvakrledleleeLrvk 197
                 N+ +l+a++g++rvH+iDfdi+qGlQWp Llq+La+R+ +p+++RiTgvg+    s++el+etg rL ++A++lg+ fef++ v++rled++l++L+vk
  Do007494.1 315 NERMLRAFDGHDRVHVIDFDIKQGLQWPGLLQSLATRAIPPAHVRITGVGE----SRQELQETGARLGRVAAALGLAFEFHA-VVDRLEDVRLWMLHVK 408
                 ***************************************************....9**************************.7*************** PP

        GRAS 198 pgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfdsl.eaklpreseerikvErellgreiv 295
                 +gE++aVn+vl+ hrll++++  +   +++L l +s+ + ++ + e+e  +ns+ + +rf++al+yy+a fd++ +a+l+++s +r+k E++ ++rei+
  Do007494.1 409 RGECVAVNCVLAAHRLLRDDTGAAL--TDFLGLARSTGAAILLLGEHEDALNSGLWEARFARALRYYAAAFDAVdAAGLASASPARVKAEEM-FAREIR 504
                 *****************88777766..99*********************************************9999**************.****** PP

        GRAS 296 nvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvksdgyrveee..sgslvlgWkdrpLvsvSaWr 374
                 n+va e a+r+erhe++  W++r+ee GF+++ +++++a+q +++ r+++   y+v+ +   + l+l W+d+p+++vSaW+
  Do007494.1 505 NAVAFEAADRFERHESFVGWQRRMEEGGFQNAGIGDREAMQGRMIARMFAPGNYTVQTQgdGEGLTLRWMDQPMYTVSAWT 585
                 **************************************************555***9654367788**************6 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5098554.779189563IPR005202Transcription factor GRAS
PfamPF035144.4E-115216585IPR005202Transcription factor GRAS
Sequence ? help Back to Top
Protein Sequence    Length: 611 aa     Download sequence    Send to blast
MLAGCSFSSS RHQMSTAQRF DILPCGFSKR GNRGDGGAAP RVAAGDAATC SFRAHPAPPV  60
TQAVSWGAKP EPGGNGAGGV WERSRAVKRA HDEGAGDEYG GGPVVRAKRT KMGGDGDEVW  120
FHPSIAGTMQ AAGAGDGEEP EEEKVFLVPS AAAFPHAGPS LATAKKEELS KSPSNSPASS  180
AGTDGGSSAV PPPLELHARN GVPAQGEAGR EAMELVVALT ACADSLAARN HDAANYYLAR  240
LGEMASPVGP TPMHRVAAYF AEALALRVVR TWPNVFDVTP PRELTDGAVG DDDATALRIL  300
NAITPIPRFL HFTLNERMLR AFDGHDRVHV IDFDIKQGLQ WPGLLQSLAT RAIPPAHVRI  360
TGVGESRQEL QETGARLGRV AAALGLAFEF HAVVDRLEDV RLWMLHVKRG ECVAVNCVLA  420
AHRLLRDDTG AALTDFLGLA RSTGAAILLL GEHEDALNSG LWEARFARAL RYYAAAFDAV  480
DAAGLASASP ARVKAEEMFA REIRNAVAFE AADRFERHES FVGWQRRMEE GGFQNAGIGD  540
REAMQGRMIA RMFAPGNYTV QTQGDGEGLT LRWMDQPMYT VSAWTPVGDG GGGGSTVSAS  600
VSTTASHSQQ S
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_A8e-6122258625379Protein SCARECROW
5b3h_D8e-6122258625379Protein SCARECROW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that acts as positivie regulator of brassinosteroid (BR) signaling (PubMed:19220793, PubMed:22685166). Functions downstream of BRI1 and GSK2 to modulate BR responses. Acts as a direct target of GSK2 kinase to mediate BR responses (PubMed:22685166). Involved in feedback inhibition of BR biosynthetic genes. Repressed by BZR1 (PubMed:19220793). {ECO:0000269|PubMed:19220793, ECO:0000269|PubMed:22685166}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapDo007494.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by 24-epibrassinolide. {ECO:0000269|PubMed:19220793}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAP0011680.0AP001168.1 Oryza sativa Japonica Group genomic DNA, chromosome 6, clone:P0425F02.
GenBankAP0028380.0AP002838.2 Oryza sativa Japonica Group genomic DNA, chromosome 6, BAC clone:OSJNBa0038F22.
GenBankAP0149620.0AP014962.1 Oryza sativa Japonica Group DNA, chromosome 6, cultivar: Nipponbare, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025812393.10.0protein DWARF AND LOW-TILLERING
SwissprotQ9LWU90.0DLT_ORYSJ; Protein DWARF AND LOW-TILLERING
TrEMBLA0A1E5WNH30.0A0A1E5WNH3_9POAL; Scarecrow-like protein 28
STRINGSi008220m0.0(Setaria italica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP64043455
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G63100.11e-118GRAS family protein
Publications ? help Back to Top
  1. Tong H,Chu C
    Roles of DLT in fine modulation on brassinosteroid response in rice.
    Plant Signal Behav, 2009. 4(5): p. 438-9
    [PMID:19816111]
  2. Li W, et al.
    Identification and characterization of dwarf 62, a loss-of-function mutation in DLT/OsGRAS-32 affecting gibberellin metabolism in rice.
    Planta, 2010. 232(6): p. 1383-96
    [PMID:20830595]
  3. Tong H, et al.
    DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice.
    Plant Cell, 2012. 24(6): p. 2562-77
    [PMID:22685166]
  4. Zhang C,Bai MY,Chong K
    Brassinosteroid-mediated regulation of agronomic traits in rice.
    Plant Cell Rep., 2014. 33(5): p. 683-96
    [PMID:24667992]
  5. Yang C,Shen W,He Y,Tian Z,Li J
    OVATE Family Protein 8 Positively Mediates Brassinosteroid Signaling through Interacting with the GSK3-like Kinase in Rice.
    PLoS Genet., 2016. 12(6): p. e1006118
    [PMID:27332964]