PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KZV20833.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Gesneriaceae; Didymocarpoideae; Trichosporeae; Loxocarpinae; Dorcoceras
Family E2F/DP
Protein Properties Length: 366aa    MW: 41558 Da    PI: 5.2504
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KZV20833.1genomeCNUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP85.34.5e-2775140171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                 r+++sL+llt+kf++l++++e+gi++ln++a +L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  KZV20833.1  75 RYDSSLGLLTKKFINLIKHAEDGILDLNKAAGTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 140
                 6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.4E-2873141IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467856.53E-1775138IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.1E-3475140IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.0E-2477140IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146605.60E-42153259No hitNo description
SuperFamilySSF1440741.78E-28154259No hitNo description
PfamPF164211.5E-30156257IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 366 aa     Download sequence    Send to blast
QLKRKSGTSN LEADYAENNM ASGSVEVVKV PFQARERVEK NPKVSRMMKT NKSSSPMKNI  60
GSSLCNNLSQ VGPCRYDSSL GLLTKKFINL IKHAEDGILD LNKAAGTLEV QKRRIYDITN  120
VLEGIGLIEK KLKNRIQWKG VYVSRPGETD VSLSSLQEDI ENLRVEEHRS DDRIRKMQEK  180
LTSLSEDVNS QKYKWLFVTD EDIKNLPCFQ NETLIAIKAP HGTTLEVPDP DEAVDYPQRR  240
YRMVLRSTMG PIDVYLVSQF EEKIEDRRAD EQPSIPEKSA AKENSLPTEE SRGNELGVAG  300
IEPERMFPGT GSAQDFVSGI MKIVPEVSND DDYWLLSDTD ISITDMWKTE CMPTQIRHFH  360
YSCFIT
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A6e-2673141574PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKZV20833.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011090314.11e-169transcription factor E2FB isoform X1
SwissprotQ9FV711e-119E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A2Z7AG900.0A0A2Z7AG90_9LAMI; Uncharacterized protein (Fragment)
STRINGMigut.N02463.1.p1e-156(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10772484
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-122E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]