PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cucsa.252760.1
Common NameCsa_3G165610, LOC101209013
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family ARR-B
Protein Properties Length: 661aa    MW: 72810.7 Da    PI: 6.0687
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cucsa.252760.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like91.47.9e-29203256155
         G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                     kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl
  Cucsa.252760.1 203 KPRVVWSVELHQQFVAAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 256
                     79*******************.********************************8 PP

2Response_reg75.91.5e-25261341109
                     EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTT CS
    Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaG 93 
                     vl+vdD+p+ +++l+++l+  +y +v+ ++ +e+al ll++++  +D++l D+ mp+mdG++ll+ i  e  +lp+i+++  + ++ + + +  G
  Cucsa.252760.1  26 VLVVDDDPTCLMILEKMLRICRY-DVTNCSRAEDALSLLRQNKngFDIVLSDVHMPDMDGFKLLEYIGLEM-DLPVIMMSVDDGKNVVMKGVTHG 118
                     89*********************.***************888889**********************6654.8********************** PP

                     ESEEEESS--HHHHHH CS
    Response_reg  94 akdflsKpfdpeelvk 109
                     a d+l Kp+ +e+l +
  Cucsa.252760.1 119 ACDYLIKPVRMEALKN 134
                     ***********99986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363921.8E-1755651IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23001.4E-4023162No hitNo description
SuperFamilySSF521728.82E-3523147IPR011006CheY-like superfamily
SMARTSM004484.1E-2824136IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011041.12225140IPR001789Signal transduction response regulator, receiver domain
PfamPF000721.2E-2226134IPR001789Signal transduction response regulator, receiver domain
CDDcd001564.96E-2527139No hitNo description
SuperFamilySSF466893.58E-20200260IPR009057Homeodomain-like
PROSITE profilePS5129411.048200259IPR017930Myb domain
Gene3DG3DSA:1.10.10.602.4E-30202261IPR009057Homeodomain-like
TIGRFAMsTIGR015579.4E-25203256IPR006447Myb domain, plants
PfamPF002499.4E-8205255IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0010082Biological Processregulation of root meristem growth
GO:0010119Biological Processregulation of stomatal movement
GO:0010150Biological Processleaf senescence
GO:0016310Biological Processphosphorylation
GO:0071368Biological Processcellular response to cytokinin stimulus
GO:0080113Biological Processregulation of seed growth
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0016301Molecular Functionkinase activity
Sequence ? help Back to Top
Protein Sequence    Length: 661 aa     Download sequence    Send to blast
MSTASSSSVR KAGEAVPDQF PAGLRVLVVD DDPTCLMILE KMLRICRYDV TNCSRAEDAL  60
SLLRQNKNGF DIVLSDVHMP DMDGFKLLEY IGLEMDLPVI MMSVDDGKNV VMKGVTHGAC  120
DYLIKPVRME ALKNIWQHVV RKRKNEWKDL EQTCVDDVDR QQKTNEDADY SSSANEGSWR  180
NSKRRKDDVE DPEERDDSST LKKPRVVWSV ELHQQFVAAV NQLGIDKAVP KKILELMNVP  240
GLTRENVASH LQKYRLYLRR LSGITQHQSN LNNTFMSAQD AFGPPLNGLD LQTLAAAGQL  300
QPQSLATLQA AGFGRSTAKS GMPMPLVDQR NHIFSFENPK LRFGDGQQPH LNGSKPMNLL  360
HGIPTTMEPK QLANLQHSAQ SHGNMTMQVS IQGGQSSSQL MQTPQPQARA QILNESTTTS  420
VTRLPQTMQP SILPNGTTSA VLARTEFGNN NRGGGYNLVS PASTMLNFPL NQTAELPGNS  480
FPLQSTPGMS SIVPKGRFPD DVNSDIKGSE GFGPSYDMFR DLHPQKPHDW DLQHVGVTFD  540
TSQGSLDIPP SAFSHQGYAS SQQNGQNRNT STAGKAMFLL EEGSDNGNAQ SMGQQLNPIF  600
VDGSVRVKSE RASDISSQTD LFSEPFGQED LMSSLFKQQQ GSIATAESEL EWLFHHNTPV  660
*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A3e-22202262464ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00054PBMTransfer from AT4G16110Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818480.0LN681848.1 Cucumis melo genomic scaffold, anchoredscaffold00006.
GenBankLN7132600.0LN713260.1 Cucumis melo genomic chromosome, chr_6.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004134232.10.0PREDICTED: two-component response regulator ARR2
SwissprotQ9ZWJ90.0ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A0A0L8000.0A0A0A0L800_CUCSA; Two-component response regulator
STRINGXP_004134232.10.0(Cucumis sativus)
STRINGXP_004162202.10.0(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF39583458
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.10.0response regulator 2
Publications ? help Back to Top
  1. Ren Y, et al.
    An integrated genetic and cytogenetic map of the cucumber genome.
    PLoS ONE, 2009. 4(6): p. e5795
    [PMID:19495411]
  2. Guo S, et al.
    Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types.
    BMC Genomics, 2010. 11: p. 384
    [PMID:20565788]
  3. Li Z, et al.
    RNA-Seq improves annotation of protein-coding genes in the cucumber genome.
    BMC Genomics, 2011. 12: p. 540
    [PMID:22047402]
  4. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  5. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  6. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  7. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  8. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  9. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  10. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  11. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  12. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]