PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PK28640.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis
Family ERF
Protein Properties Length: 109aa    MW: 12713.2 Da    PI: 11.4853
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PK28640.1genomeCCBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP253.27.2e-172271255
        AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
               +y GVr+++ +grWvAeI+d    +++ r +lg+f+t+e+Aa  +++a++ l+g
  PK28640.1 22 RYLGVRQRP-SGRWVAEIKDS---NQKLRLWLGTFDTPEDAALTYDRAARLLRG 71
               689******.7*********3...246***********************9998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000181.36E-302281No hitNo description
SuperFamilySSF541714.12E-202280IPR016177DNA-binding domain
SMARTSM003806.6E-332285IPR001471AP2/ERF domain
PfamPF008471.9E-112271IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.6E-292280IPR001471AP2/ERF domain
PROSITE profilePS5103220.312279IPR001471AP2/ERF domain
PRINTSPR003671.8E-72334IPR001471AP2/ERF domain
PRINTSPR003671.8E-74561IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 109 aa     Download sequence    Send to blast
EHHHSSMHPK RTVMLKNRLP RRYLGVRQRP SGRWVAEIKD SNQKLRLWLG TFDTPEDAAL  60
TYDRAARLLR GRNAKTNFPN QGITTSSEEN FNILGKNNPR LYQLLQQAX
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A2e-162379360ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A2e-162379663ATERF1
3gcc_A2e-162379663ATERF1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs) (PubMed:17449807, PubMed:17827349). Binds to the GCC-box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation and maintenance, and nodule development. Necessary for NF-induced gene expression and spontaneous nodulation activated by CCAMK. Functions downstream of CCAMK to activate nodulation gene expression (PubMed:17449807). Involved in early stages of root nodule development. Functions redundantly with ERN2. Is essential with ERN2 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241, ECO:0000269|PubMed:27208242}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in roots from 1 to 21 day after inoculation with Sinorhizobium meliloti (PubMed:17449807). Induced by Nod factors in root hairs (PubMed:17827349). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010110748.19e-47ethylene-responsive transcription factor ERF010
SwissprotA2Q5W16e-24ERN1_MEDTR; Ethylene-responsive transcription factor ERN1
TrEMBLA0A2P5AKL01e-59A0A2P5AKL0_PARAD; AP2/ERF transcription factor
STRINGXP_010110748.13e-46(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF123492734
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G19790.15e-26related to AP2 11
Publications ? help Back to Top
  1. Cerri MR, et al.
    Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
    Plant Physiol., 2012. 160(4): p. 2155-72
    [PMID:23077241]
  2. Tang H, et al.
    An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
    BMC Genomics, 2014. 15: p. 312
    [PMID:24767513]
  3. Cerri MR, et al.
    The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection.
    Plant Physiol., 2016. 171(2): p. 1037-54
    [PMID:27208242]