PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Carubv10009864m
Common NameCARUB_v10009864mg
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family bZIP
Protein Properties Length: 303aa    MW: 33976.8 Da    PI: 4.2834
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Carubv10009864mgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_130.11e-09147189446
                      XCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
           bZIP_1   4 lkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLk 46 
                       k+ rr+ +NR AA rsR+RKk++++ Le+k+k Le e  +L 
  Carubv10009864m 147 AKKRRRRVRNRDAAVRSRERKKEYVQDLEKKSKYLERECLRLG 189
                      699*********************************9976665 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.20.5.1702.4E-13140207No hitNo description
SMARTSM003389.7E-6141208IPR004827Basic-leucine zipper domain
PROSITE profilePS5021710.978146203IPR004827Basic-leucine zipper domain
PfamPF077161.9E-9148190IPR004827Basic-leucine zipper domain
SuperFamilySSF579593.06E-11148206No hitNo description
PROSITE patternPS000360151166IPR004827Basic-leucine zipper domain
CDDcd147049.29E-13158200No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010200Biological Processresponse to chitin
GO:0030968Biological Processendoplasmic reticulum unfolded protein response
GO:0005634Cellular Componentnucleus
GO:0005789Cellular Componentendoplasmic reticulum membrane
GO:0016021Cellular Componentintegral component of membrane
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 303 aa     Download sequence    Send to blast
MAEEFDSFDL LFDDDLFFDF DPSIVIDSPP AEEDFVRSSP DSWIGEIESK LMSDENQEEE  60
SLAELDQGSI SEFIADLLVD YPVDLTTEQA TAGKETEGSD DSAGKETVGS DDSGKESADL  120
VVEKKSNDSG SEVQDDDEEG DDDDAGAKKR RRRVRNRDAA VRSRERKKEY VQDLEKKSKY  180
LERECLRLGR MLECFVAENQ SLRYCLQKGS GNNIPMMSRQ ESAVLLLESL LLGSLLWLLG  240
VNFICLFPYL SHTKCYLLKS EPEKLVLNEL GSSSNPSNTG VSRRCKGSRP RMKHQNLTLV  300
LR*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1147152KKRRRR
2148153KRRRRV
3148167KRRRRVRNRDAAVRSRERKK
4150167RRRVRNRDAAVRSRERKK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Plays a role in plant immunity and abiotic stress responses. {ECO:0000269|PubMed:15781873, ECO:0000269|PubMed:18574595, ECO:0000269|PubMed:19017746, ECO:0000269|PubMed:21482766, ECO:0000269|PubMed:22359644}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00019PBMTransfer from AT1G42990Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCarubv10009864m
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tunicamycin, DTT and azetidine-2-carboxylate. Isoform 2 is induced by heat. {ECO:0000269|PubMed:15781873, ECO:0000269|PubMed:21482766}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0459640.0AY045964.1 Arabidopsis thaliana putative bZIP transcription factor (At1g42990) mRNA, complete cds.
GenBankAY1338050.0AY133805.1 Arabidopsis thaliana clone U10320 putative bZIP transcription factor (At1g42990) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006305453.10.0bZIP transcription factor 60
SwissprotQ9C7S01e-120BZP60_ARATH; bZIP transcription factor 60
TrEMBLR0GRD50.0R0GRD5_9BRAS; Uncharacterized protein
STRINGXP_006305453.10.0(Capsella rubella)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM46342848
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G42990.11e-110basic region/leucine zipper motif 60
Publications ? help Back to Top
  1. Deng Y,Srivastava R,Howell SH
    Protein kinase and ribonuclease domains of IRE1 confer stress tolerance, vegetative growth, and reproductive development in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(48): p. 19633-8
    [PMID:24145452]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Nagashima Y,Iwata Y,Ashida M,Mishiba K,Koizumi N
    Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis.
    Plant Cell Physiol., 2014. 55(10): p. 1772-8
    [PMID:25138441]
  4. Parra-Rojas J,Moreno AA,Mitina I,Orellana A
    The dynamic of the splicing of bZIP60 and the proteins encoded by the spliced and unspliced mRNAs reveals some unique features during the activation of UPR in Arabidopsis thaliana.
    PLoS ONE, 2015. 10(4): p. e0122936
    [PMID:25860807]
  5. Zhang L,Chen H,Brandizzi F,Verchot J,Wang A
    The UPR branch IRE1-bZIP60 in plants plays an essential role in viral infection and is complementary to the only UPR pathway in yeast.
    PLoS Genet., 2015. 11(4): p. e1005164
    [PMID:25875739]
  6. Walley J, et al.
    Plastid-produced interorgannellar stress signal MEcPP potentiates induction of the unfolded protein response in endoplasmic reticulum.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(19): p. 6212-7
    [PMID:25922532]
  7. Ma ZX, et al.
    The THERMOSENSITIVE MALE STERILE 1 Interacts with the BiPs via DnaJ Domain and Stimulates Their ATPase Enzyme Activities in Arabidopsis.
    PLoS ONE, 2015. 10(7): p. e0132500
    [PMID:26186593]
  8. Sagor GH, et al.
    The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 687
    [PMID:26442007]
  9. Deng Y, et al.
    IRE1, a component of the unfolded protein response signaling pathway, protects pollen development in Arabidopsis from heat stress.
    Plant J., 2016. 88(2): p. 193-204
    [PMID:27304577]
  10. Gaguancela OA, et al.
    The IRE1/bZIP60 Pathway and Bax Inhibitor 1 Suppress Systemic Accumulation of Potyviruses and Potexviruses in Arabidopsis and Nicotiana benthamiana Plants.
    Mol. Plant Microbe Interact., 2016. 29(10): p. 750-766
    [PMID:27578623]
  11. Meng Z,Ruberti C,Gong Z,Brandizzi F
    CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses.
    Plant J., 2017. 89(3): p. 486-501
    [PMID:27747970]
  12. Wang B,Du H,Zhang Z,Xu W,Deng X
    BhbZIP60 from Resurrection Plant Boea hygrometrica Is an mRNA Splicing-Activated Endoplasmic Reticulum Stress Regulator Involved in Drought Tolerance.
    Front Plant Sci, 2017. 8: p. 245
    [PMID:28286511]
  13. Li Q, et al.
    Unfolded protein response activation compensates endoplasmic reticulum-associated degradation deficiency in Arabidopsis.
    J Integr Plant Biol, 2017. 59(7): p. 506-521
    [PMID:28418178]
  14. Zhang SS, et al.
    Tissue-Specific Transcriptomics Reveals an Important Role of the Unfolded Protein Response in Maintaining Fertility upon Heat Stress in Arabidopsis.
    Plant Cell, 2017. 29(5): p. 1007-1023
    [PMID:28442596]
  15. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  16. Ruberti C,Lai Y,Brandizzi F
    Recovery from temporary endoplasmic reticulum stress in plants relies on the tissue-specific and largely independent roles of bZIP28 and bZIP60, as well as an antagonizing function of BAX-Inhibitor 1 upon the pro-adaptive signaling mediated by bZIP28.
    Plant J., 2018. 93(1): p. 155-165
    [PMID:29124827]
  17. Kim JS,Yamaguchi-Shinozaki K,Shinozaki K
    ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation.
    Plant Physiol., 2018. 176(3): p. 2221-2230
    [PMID:29367234]