PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_69296_iso_1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family ERF
Protein Properties Length: 212aa    MW: 23667.9 Da    PI: 9.2876
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_69296_iso_1genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP268.41.3e-2159108255
                                  AP2   2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                                          +y+G+r+++ +g+W+AeIrdp     +  r++lg+f taeeAa+a+++a+k+++g
  cra_locus_69296_iso_1_len_634_ver_3  59 KYRGIRQRP-WGKWAAEIRDPQ----QgVRVWLGTFNTAEEAARAYDEAAKRIRG 108
                                          8********.**********94....25************************997 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003801.4E-4059122IPR001471AP2/ERF domain
PROSITE profilePS5103224.2559116IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.1E-3359117IPR001471AP2/ERF domain
CDDcd000181.63E-3559117No hitNo description
SuperFamilySSF541717.19E-2359116IPR016177DNA-binding domain
PfamPF008473.3E-1559108IPR001471AP2/ERF domain
PRINTSPR003674.5E-126071IPR001471AP2/ERF domain
PRINTSPR003674.5E-128298IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008219Biological Processcell death
GO:0009723Biological Processresponse to ethylene
GO:0009735Biological Processresponse to cytokinin
GO:0009753Biological Processresponse to jasmonic acid
GO:0010286Biological Processheat acclimation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051707Biological Processresponse to other organism
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0005886Cellular Componentplasma membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 212 aa     Download sequence    Send to blast
XGRGTPSLSF SFTPKKERKT IAKTVTSGGA DSAKHKQLQK DTSVKVEKES SGARPRKNKY  60
RGIRQRPWGK WAAEIRDPQQ GVRVWLGTFN TAEEAARAYD EAAKRIRGDK AKLNFPNPPS  120
PPAKRQCTTT LPDLPALLES SNIVSDNPSL MNFGYQNQAS YYPIEIPAAE ENHHDEYELK  180
EQISNLESFL ELDQPDSSQF SGIVNSDPIN IX
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2gcc_A4e-2360116663ATERF1
3gcc_A4e-2360116663ATERF1
5wx9_A6e-2346117173Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:9159183}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00109PBMTransfer from AT3G16770Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By 1-aminocyclopropane-1-carboxylic acid (ACC, ethylene precursor), methyl jasmonate (MeJA), and Botrytis cinerea. Also induced by cadmium. {ECO:0000269|PubMed:18836139, ECO:0000269|PubMed:9159183}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019237585.17e-93PREDICTED: ethylene-responsive transcription factor RAP2-3
SwissprotP427361e-39RAP23_ARATH; Ethylene-responsive transcription factor RAP2-3
TrEMBLA0A2G2XPC03e-95A0A2G2XPC0_CAPBA; Ethylene-responsive transcription factor 1
STRINGXP_009597158.19e-88(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA21241165
Publications ? help Back to Top
  1. Bueso E, et al.
    The lithium tolerance of the Arabidopsis cat2 mutant reveals a cross-talk between oxidative stress and ethylene.
    Plant J., 2007. 52(6): p. 1052-65
    [PMID:17931347]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Chen YC, et al.
    Root defense analysis against Fusarium oxysporum reveals new regulators to confer resistance.
    Sci Rep, 2014. 4: p. 5584
    [PMID:24998294]
  4. Deslauriers SD,Alvarez AA,Lacey RF,Binder BM,Larsen PB
    Dominant gain-of-function mutations in transmembrane domain III of ERS1 and ETR1 suggest a novel role for this domain in regulating the magnitude of ethylene response in Arabidopsis.
    New Phytol., 2015. 208(2): p. 442-55
    [PMID:25988998]
  5. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
    [PMID:26025519]
  6. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
    [PMID:26668304]
  7. Liu W, et al.
    Ethylene response factor AtERF72 negatively regulates Arabidopsis thaliana response to iron deficiency.
    Biochem. Biophys. Res. Commun., 2017. 491(3): p. 862-868
    [PMID:28390898]
  8. Yao Y,Chen X,Wu AM
    ERF-VII members exhibit synergistic and separate roles in Arabidopsis.
    Plant Signal Behav, 2017. 12(6): p. e1329073
    [PMID:28537474]