PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_4762_iso_7
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family C2H2
Protein Properties Length: 214aa    MW: 24668.6 Da    PI: 7.3587
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_4762_iso_7genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H218.65e-061034123
                                         EEET..TTTEEESSHHHHHHHHHHT CS
                              zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                                         + Cp  dCgk++ + + Lk+Hi++H
  cra_locus_4762_iso_7_len_1214_ver_3 10 HICPyaDCGKRYAHEYKLKNHISSH 34
                                         68**********************6 PP

2zf-C2H217.11.6e-057297123
                                         EEET..TTTEEESSHHHHHHHHHH.T CS
                              zf-C2H2  1 ykCp..dCgksFsrksnLkrHirt.H 23
                                         y+Cp   C+k + + + L+ H+r+ H
  cra_locus_4762_iso_7_len_1214_ver_3 72 YTCPyeGCDKAYIHEYKLNLHLRReH 97
                                         9***********************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.7E-8136IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576677.05E-6136No hitNo description
SMARTSM003550.00691034IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.2451039IPR007087Zinc finger, C2H2
PROSITE patternPS0002801235IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.4E-96695IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.85E-66695No hitNo description
SMARTSM003550.00197297IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.09772102IPR007087Zinc finger, C2H2
PROSITE patternPS0002807497IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 214 aa     Download sequence    Send to blast
MKTHSQENYH ICPYADCGKR YAHEYKLKNH ISSHHEKNVV EPTKYVPPAE KPVKTPKSSN  60
ATYASASSDR PYTCPYEGCD KAYIHEYKLN LHLRREHPGH SKEENAKNVQ FTADNDMDEA  120
SDHDPYPAKR SNDKKPSRSK PNLKLPPAKV AQRKGSTASQ ANMSVMKKQW PVKEEVYDEE  180
DSEETEEERD NVVMVGDMQX XXXXXXXXXX RDRV
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027162703.15e-86zinc finger transcription factor YY1
SwissprotQ2V3L35e-60YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A0D2QA253e-85A0A0D2QA25_GOSRA; Uncharacterized protein
TrEMBLA0A2N9HQ804e-85A0A2N9HQ80_FAGSY; Uncharacterized protein
STRINGGorai.002G214700.13e-84(Gossypium raimondii)
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]