PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_384_iso_8
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family C2H2
Protein Properties Length: 442aa    MW: 50977.1 Da    PI: 8.3724
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_384_iso_8genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H221.56.1e-07107128223
                                         EETTTTEEESSHHHHHHHHHHT CS
                             zf-C2H2   2 kCpdCgksFsrksnLkrHirtH 23 
                                         +C+ Cg sF+ + +L++H+++H
  cra_locus_384_iso_8_len_1601_ver_3 107 VCHECGVSFKKPAYLRQHMQSH 128
                                         6*******************99 PP

2zf-C2H217.89.2e-06160184123
                                         EEET..TTTEEESSHHHHHHHHHHT CS
                             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                                         ++Cp  dC+ s++rk++L+rH+  H
  cra_locus_384_iso_8_len_1601_ver_3 160 FTCPvdDCHSSYRRKDHLTRHLLQH 184
                                         89*******************9887 PP

3zf-C2H214.88.3e-05189214123
                                         EEET..TTTEEESSHHHHHHHHHH.T CS
                             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                                         ++Cp  +C  +F  + n+krH++  H
  cra_locus_384_iso_8_len_1601_ver_3 189 FECPgdNCQSRFAFQGNMKRHMKEfH 214
                                         89*********************988 PP

4zf-C2H218.26.6e-06228252123
                                         EEET..TTTEEESSHHHHHHHHHHT CS
                             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                                         y+C+   Cgk+F+  s L++H  +H
  cra_locus_384_iso_8_len_1601_ver_3 228 YVCSefGCGKVFKFASKLRKHEDSH 252
                                         99*******************9888 PP

5zf-C2H214.40.00011319343223
                                         EET..TTTEEESSHHHHHHHHHH.T CS
                             zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                                         kC+   C  +Fs+ snL++Hi+  H
  cra_locus_384_iso_8_len_1601_ver_3 319 KCSfdGCAHTFSTMSNLNQHIKAvH 343
                                         688889***************9888 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.24E-660129No hitNo description
SMARTSM00355326284IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.608.9E-698129IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0098106128IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.658106133IPR007087Zinc finger, C2H2
PROSITE patternPS000280108128IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.6E-8157186IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576676.83E-6157186No hitNo description
SMARTSM003550.0059160184IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.64160189IPR007087Zinc finger, C2H2
PROSITE patternPS000280162184IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.2E-4187215IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576672.02E-5187215No hitNo description
SMARTSM003550.28189214IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.432189219IPR007087Zinc finger, C2H2
PROSITE patternPS000280191214IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.4E-7222252IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0073228252IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.157228257IPR007087Zinc finger, C2H2
PROSITE patternPS000280230252IPR007087Zinc finger, C2H2
SMARTSM003550.63260285IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280262285IPR007087Zinc finger, C2H2
SMARTSM0035516288309IPR015880Zinc finger, C2H2-like
SuperFamilySSF576674.66E-7301356No hitNo description
SMARTSM003550.0049318343IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.637318348IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.7E-5319344IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280320343IPR007087Zinc finger, C2H2
SMARTSM0035516349375IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280351375IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008097Molecular Function5S rRNA binding
GO:0046872Molecular Functionmetal ion binding
GO:0080084Molecular Function5S rDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 442 aa     Download sequence    Send to blast
XXWELAALAE CECALLSTPG FLTKSGAPHR NSSTSPLSEI VSKVEMVEEK SKPVIFRDIR  60
RYYCEYCGIC RSKKALISAH ILSHHQDDLK QGEEDKRETH NGPKMNVCHE CGVSFKKPAY  120
LRQHMQSHSL EAVKHWIPHK ELQNARGQCX LECDQYQRPF TCPVDDCHSS YRRKDHLTRH  180
LLQHQGKLFE CPGDNCQSRF AFQGNMKRHM KEFHKEPYSS DEESPKQYVC SEFGCGKVFK  240
FASKLRKHED SHVKLETVEA FCSEPGCMKY FTNEQCLKEH IRSCHQHITC EKCGTRQLKK  300
NIKRHLRMHE AGVSSERTKC SFDGCAHTFS TMSNLNQHIK AVHLELTPFA CGFPGCGMKF  360
SFKHVRDHHE KSSRHVYSHG DFEASDEQFR SRPRGGRKRK YPVIETLMRK RIVPPGEADP  420
ILNNGSEYLS RLLSSGESED DM
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A3e-1215728040155PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D3e-1215728040155PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1391399RPRGGRKRK
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00229DAPTransfer from AT1G72050Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027098504.10.0transcription factor IIIA-like
SwissprotQ84MZ41e-134TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A068V6C10.0A0A068V6C1_COFCA; Uncharacterized protein
STRINGVIT_08s0040g00240.t010.0(Vitis vinifera)