PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_384_iso_3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family C2H2
Protein Properties Length: 338aa    MW: 39248.4 Da    PI: 8.6828
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_384_iso_3genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2224.4e-07324223
                                        EETTTTEEESSHHHHHHHHHHT CS
                             zf-C2H2  2 kCpdCgksFsrksnLkrHirtH 23
                                        +C+ Cg sF+ + +L++H+++H
  cra_locus_384_iso_3_len_1770_ver_3  3 VCHECGVSFKKPAYLRQHMQSH 24
                                        6*******************99 PP

2zf-C2H218.36.5e-065680123
                                        EEET..TTTEEESSHHHHHHHHHHT CS
                             zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                                        ++Cp  dC+ s++rk++L+rH+  H
  cra_locus_384_iso_3_len_1770_ver_3 56 FTCPvdDCHSSYRRKDHLTRHLLQH 80
                                        89*******************9887 PP

3zf-C2H217.98.8e-0685110123
                                         EEET..TTTEEESSHHHHHHHHHH.T CS
                             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                                         ++Cp  +C+++F  + n++rH++  H
  cra_locus_384_iso_3_len_1770_ver_3  85 FECPvdNCKRRFAFQGNMRRHMKEfH 110
                                         89*********************988 PP

4zf-C2H2201.8e-06124148123
                                         EEET..TTTEEESSHHHHHHHHHHT CS
                             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                                         y+C+   Cgk+F+  s L++H  +H
  cra_locus_384_iso_3_len_1770_ver_3 124 YVCSeiGCGKVFKYASKLRKHEDSH 148
                                         99*******************9888 PP

5zf-C2H214.97.9e-05215239223
                                         EET..TTTEEESSHHHHHHHHHH.T CS
                             zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                                         kC+   C  +Fs+ snL++Hi+  H
  cra_locus_384_iso_3_len_1770_ver_3 215 KCSfdGCAHTFSTMSNLNQHIKAvH 239
                                         688889***************9888 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5015710.658229IPR007087Zinc finger, C2H2
SMARTSM003550.0098224IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.602.6E-5325IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280424IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.1E-85382IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576674.78E-65382No hitNo description
SMARTSM003550.00595680IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.645685IPR007087Zinc finger, C2H2
PROSITE patternPS0002805880IPR007087Zinc finger, C2H2
SuperFamilySSF576672.99E-683110No hitNo description
Gene3DG3DSA:3.30.160.602.3E-683107IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.00585110IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.22185115IPR007087Zinc finger, C2H2
PROSITE patternPS00028087110IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.0E-7121148IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.73E-5121150No hitNo description
SMARTSM003550.0015124148IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.427124153IPR007087Zinc finger, C2H2
PROSITE patternPS000280126148IPR007087Zinc finger, C2H2
SMARTSM003550.63156181IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280158181IPR007087Zinc finger, C2H2
SMARTSM0035516184205IPR015880Zinc finger, C2H2-like
SuperFamilySSF576671.12E-6197252No hitNo description
SMARTSM003550.0049214239IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.637214244IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.2E-5215240IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280216239IPR007087Zinc finger, C2H2
SMARTSM0035516245271IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280247271IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008097Molecular Function5S rRNA binding
GO:0046872Molecular Functionmetal ion binding
GO:0080084Molecular Function5S rDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 338 aa     Download sequence    Send to blast
MNVCHECGVS FKKPAYLRQH MQSHSLEAVK HWIPHKELQN ARGQCXLECD QYQRPFTCPV  60
DDCHSSYRRK DHLTRHLLQH QGKLFECPVD NCKRRFAFQG NMRRHMKEFH MEPSSSDEVS  120
AKQYVCSEIG CGKVFKYASK LRKHEDSHVK LETVEAFCSE PGCMKYFTNE QCLKEHIRSC  180
HQHITCEKCG TRQLKKNIKR HLRMHEAGVS SERTKCSFDG CAHTFSTMSN LNQHIKAVHL  240
ELTPFACGFP GCGMKFSFKH VRDHHEKSSR HVYSHGDFEA SDEQFRSRPR GGRKRKYPVI  300
ETLMRKRIVP PGEADPILNN GSEYLSRLLS SGESEDDM
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A7e-135317640155PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D7e-135317640155PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1287295RPRGGRKRK
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00229DAPTransfer from AT1G72050Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027098504.11e-172transcription factor IIIA-like
SwissprotQ84MZ42e-98TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A068V6C11e-174A0A068V6C1_COFCA; Uncharacterized protein
STRINGVIT_08s0040g00240.t011e-169(Vitis vinifera)