PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_12822_iso_1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family bHLH
Protein Properties Length: 366aa    MW: 40337.5 Da    PI: 4.8054
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_12822_iso_1genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH33.57.6e-11189234555
                                           HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
                                   HLH   5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                                           h ++Er+RR+++ + f  L  ++P +     kK++K ++L  A+ Y+k++q
  cra_locus_12822_iso_1_len_1418_ver_3 189 HIIAERKRREQLSQHFVALSAIVPGL-----KKMDKTSVLGDAITYLKHMQ 234
                                           899***********************.....9******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088814.068184233IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.03E-15185250IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.46E-10189238No hitNo description
Gene3DG3DSA:4.10.280.105.1E-15189247IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.8E-8189234IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.9E-12190239IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 366 aa     Download sequence    Send to blast
MTMMMTMDNS VNSWFSDLGM EDPFSSDQYD ITDFLNEDFA ALGEDLQAFT PTAESDSSNN  60
FINIPTSNSS NTLCALATEL PSVVAEIPTT ITATTTTKKR KSNSSTNQNV PNARRAARTP  120
IVLTFGNTTA ETNPNKHSLS PDINDDSLIS TENLTSQGNL EEAVAAAKST KLNKKTGGRV  180
RPASQTYDHI IAERKRREQL SQHFVALSAI VPGLKKMDKT SVLGDAITYL KHMQERVKTL  240
EEQTTKQTME SVVLVKKSQV LVEDEGSSDE IDQDQSSSQL PEIEAKVCDK TILLRVHCEK  300
NKRVLINILS QLEKLNLVVT NTSVSAFGSL ALDITIIVEM EKESSINMKE LIQTLRSAVM  360
RANLED
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1192197ERKRRE
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027103298.11e-127transcription factor bHLH18-like
TrEMBLA0A0H3V2H60.0A0A0H3V2H6_CATRO; BHLH iridoid synthesis 1
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA17602461
Publications ? help Back to Top
  1. Van Moerkercke A, et al.
    The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(26): p. 8130-5
    [PMID:26080427]