PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_1271_iso_1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family C2H2
Protein Properties Length: 520aa    MW: 57718.1 Da    PI: 6.4632
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_1271_iso_1genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2218.7e-07270291223
                                          EETTTTEEESSHHHHHHHHHHT CS
                              zf-C2H2   2 kCpdCgksFsrksnLkrHirtH 23 
                                           C++Cgk F+r  nL+ H+r H
  cra_locus_1271_iso_1_len_1915_ver_3 270 FCTICGKGFKRDANLRMHMRGH 291
                                          6*******************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.47E-5267294No hitNo description
SMARTSM003550.0026269291IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.03269296IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.607.7E-6270320IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280271291IPR007087Zinc finger, C2H2
SMARTSM0035558318351IPR015880Zinc finger, C2H2-like
SMARTSM0035531356378IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010044Biological Processresponse to aluminum ion
GO:0010447Biological Processresponse to acidic pH
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 520 aa     Download sequence    Send to blast
MDPDERQSAK AWTPSGNDVL KNLSMDNQSF IDFGLQQKWE DCSYLGYQSR IEQGFSKFSH  60
QSENSSSVDG SSNSQSKIQG RQDSRMQEAS NSNKMPDWDP KGMLSNLSFL EQKIHQLQGL  120
VQLIVGRRGQ VENQSNELLV QQQQLIIADL TSIIVQLIST AGSLLPSAKH TLSSVSPYVP  180
QFRQFGGSMV PSGTNASSGG GLPQNTVNKV EDQSQEIDLT GHHGTEQNFA VEEHEMKDED  240
DGEEGENLPP GSYEILQLEK EEILAPHTHF CTICGKGFKR DANLRMHMRG HGDEYKTPAA  300
LAKPHKESSS EPALIKRYSC PYVGCKRNKD HKKFQPLKTI LCVKNHYKRT HCDKSYTCSR  360
CHTKKFSVVA DLKTHEKHCG RDKWLCSCGT TFSRKDKLFG HIALFQGHTP AIPMDDSKGS  420
AGTSDGLQSS EAVNKIEQLD FSAQSNIPSG SCFENVMDGK GSVDDPVNYF SPLNFDPSNL  480
SGYQEFPRPS FEDSESSFSF LLSGSAQYDQ KSGRYSGPVI
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269|PubMed:17535918, ECO:0000269|PubMed:18826429, ECO:0000269|PubMed:19321711, ECO:0000269|PubMed:23935008}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00196ampDAPTransfer from AT1G34370Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269|PubMed:17535918}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027094877.10.0protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like isoform X1
RefseqXP_027094901.10.0protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like isoform X1
SwissprotQ9C8N50.0STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBLA5BSF50.0A5BSF5_VITVI; Uncharacterized protein
STRINGXP_008237278.10.0(Prunus mume)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA47542441
Publications ? help Back to Top
  1. Kobayashi Y, et al.
    Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions.
    Plant Physiol., 2013. 163(1): p. 180-92
    [PMID:23839867]
  2. Yokosho K,Yamaji N,Ma JF
    Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench).
    Plant Cell Physiol., 2014. 55(12): p. 2077-91
    [PMID:25273892]
  3. Geng X, et al.
    LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.
    Plant J., 2017. 90(3): p. 491-504
    [PMID:28181322]
  4. Balzergue C, et al.
    Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation.
    Nat Commun, 2017. 8: p. 15300
    [PMID:28504266]
  5. Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A
    Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation.
    Front Plant Sci, 2017. 8: p. 822
    [PMID:28567051]
  6. Jiang F, et al.
    Identification and characterization of suppressor mutants of stop1.
    BMC Plant Biol., 2017. 17(1): p. 128
    [PMID:28738784]
  7. Daspute AA, et al.
    Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
    Front Plant Sci, 2017. 8: p. 1358
    [PMID:28848571]
  8. Sharma A,Wai CM,Ming R,Yu Q
    Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis.
    Genome Biol Evol, 2017. 9(9): p. 2170-2190
    [PMID:28922793]
  9. Zhang Y, et al.
    The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 118
    [PMID:29491872]