PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID maker-scaffold08188-augustus-gene-0.7-mRNA-1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fagales; Fagaceae; Castanea
Family NAC
Protein Properties Length: 160aa    MW: 18507.8 Da    PI: 7.2139
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
maker-scaffold08188-augustus-gene-0.7-mRNA-1genomeTHGPView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM133.11.9e-4191371127
                                           NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFsk 63 
                                                   lp GfrF+Ptdeel+++yL+ k eg++  + +vi+ev+ y+++Pw+Lp  +++++++++w+fF+k
  maker-scaffold08188-augustus-gene-0.7-mRNA-1   9 LPLGFRFSPTDEELINHYLRLKNEGHDSGV-QVIAEVNFYEFDPWELPdlSAIESSNEQWFFFCK 72 
                                                   699************************988.99**************96448888999******9 PP

                                           NAM  64 rdkkyatgkrknratksgyWkatgkdkevlsk.....kgelvglkktLvfykgrapkgektdWvm 123
                                                    + +    ++ nratksgyWkatgk+++++s+     +++l+g+kktLv+++g++pkg++++Wv+
  maker-scaffold08188-augustus-gene-0.7-mRNA-1  73 LKIA----SHFNRATKSGYWKATGKERHITSRkwgpsNSSLIGIKKTLVYHTGHDPKGKRSNWVV 133
                                                   9776....479********************9999988899************************ PP

                                           NAM 124 heyr 127
                                                   +ey+
  maker-scaffold08188-augustus-gene-0.7-mRNA-1 134 NEYH 137
                                                   ***8 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019411.28E-425143IPR003441NAC domain
PROSITE profilePS5100541.229160IPR003441NAC domain
PfamPF023654.7E-2410137IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 160 aa     Download sequence    Send to blast
MANLSLESLP LGFRFSPTDE ELINHYLRLK NEGHDSGVQV IAEVNFYEFD PWELPDLSAI  60
ESSNEQWFFF CKLKIASHFN RATKSGYWKA TGKERHITSR KWGPSNSSLI GIKKTLVYHT  120
GHDPKGKRSN WVVNEYHDIA TRQVCFLEKQ NFSLESQEIA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A1e-33413915146NAC domain-containing protein 19
3swm_B1e-33413915146NAC domain-containing protein 19
3swm_C1e-33413915146NAC domain-containing protein 19
3swm_D1e-33413915146NAC domain-containing protein 19
3swp_A1e-33413915146NAC domain-containing protein 19
3swp_B1e-33413915146NAC domain-containing protein 19
3swp_C1e-33413915146NAC domain-containing protein 19
3swp_D1e-33413915146NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator essential for the anti-viral defense called virus basal resistance response pathway (PubMed:11041886, PubMed:15629774, PubMed:18785827, PubMed:24418554). Not involved in HRT-mediated hypersensitive response (HR) and resistance to TCV (PubMed:18785827). Binds DNA non specifically (PubMed:15629774). Activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (By similarity). {ECO:0000250|UniProtKB:Q9SCK6, ECO:0000269|PubMed:11041886, ECO:0000269|PubMed:15629774, ECO:0000269|PubMed:18785827, ECO:0000269|PubMed:24418554}.; FUNCTION: (Microbial infection) Compromised function in defense response pathway when interacting with the invading viral capsid protein (CP) of turnip crinkle virus (TCV) due to abnormal subcellular localization. {ECO:0000269|PubMed:11041886, ECO:0000269|PubMed:15629774}.
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (PubMed:18443413, PubMed:24329768). Calmodulin-regulated transcriptional repressor. Binds several synthetic promoters with randomly selected binding sites (PubMed:17947243). Functions synergistically with SNI1 as negative regulator of pathogen-induced PR1 expression and basal resistance to a virulent strain of P.syringae. Binds directly to the promoter of the PR1 gene (PubMed:22826500). Acts as positive regulator of innate immunity. Involved in the effector-triggered immunity (ETI) induction of immunity-related gene expression (PubMed:24329768). Mediates osmotic stress signaling in leaf senescence by up-regulating senescence-associated genes (PubMed:18443413). {ECO:0000269|PubMed:17947243, ECO:0000269|PubMed:18443413, ECO:0000269|PubMed:22826500, ECO:0000269|PubMed:24329768}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by bacterial pathogens type III effector proteins (TTEs). {ECO:0000269|PubMed:16553893}.; INDUCTION: (Microbial infection) Accumulates 2 days post infection with turnip crinkle virus (TCV) (PubMed:24418554). {ECO:0000269|PubMed:24418554}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023877826.11e-74NAC domain-containing protein 91-like
RefseqXP_023880191.13e-70disease resistance protein At4g27190-like
SwissprotF4JN351e-46NTL9_ARATH; Protein NTM1-like 9
SwissprotQ9LKG86e-47NAC91_ARATH; NAC domain-containing protein 91
TrEMBLA0A3Q8TBI55e-49A0A3Q8TBI5_DIOKA; Transcription factor NAC10
STRINGXP_006476249.11e-47(Citrus sinensis)
STRINGXP_008360722.12e-47(Malus domestica)
STRINGcassava4.1_032341m5e-49(Manihot esculenta)
STRINGXP_006439176.11e-47(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF20652586
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G24590.23e-49TCV-interacting protein
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Zheng XY, et al.
    Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(30): p. 9166-73
    [PMID:26139525]
  3. Ben Daniel BH, et al.
    Identification of novel transcriptional regulators of Zat12 using comprehensive yeast one-hybrid screens.
    Physiol Plant, 2016. 157(4): p. 422-41
    [PMID:26923089]
  4. Li Y, et al.
    The interaction between Turnip crinkle virus p38 and Cucumber mosaic virus 2b and its critical domains.
    Virus Res., 2016. 222: p. 94-105
    [PMID:27288723]
  5. Guo T, et al.
    Lamin-like Proteins Negatively Regulate Plant Immunity through NAC WITH TRANSMEMBRANE MOTIF1-LIKE9 and NONEXPRESSOR OF PR GENES1 in Arabidopsis thaliana.
    Mol Plant, 2017. 10(10): p. 1334-1348
    [PMID:28943325]