PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C025774P1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family HD-ZIP
Protein Properties Length: 541aa    MW: 59602.1 Da    PI: 8.2056
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C025774P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.55.6e-192583357
                    --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
        Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                    k  ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  MELO3C025774P1 25 KYVRYTSEQVEALERVYAECPKPSSLRRQQLVRECpilsNIEPKQIKVWFQNRRCREKQ 83
                    5678*****************************************************97 PP

2START155.25.4e-491653732205
                     HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlm 94 
                     +aee+++e+++ka+ ++  Wv+++ +++g++++ +f+ s+++ g a+ra+g+v  ++    +e+l+d++ W +++++ e+      g  g+++l 
  MELO3C025774P1 165 IAEETLAEFLSKATGTAVDWVQMPGMKPGPDSVGIFAISQSCGGVAARACGLVSLEPS-KIAEILKDRPSWFRDCRSLEVFTMFPAGngGTIELV 258
                     7899******************************************************.7777777777***********999999999****** PP

                     EEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHH CS
           START  95 vaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslv 185
                     +++ +a+++l+p Rdf+++Ry+ +l+ g++v++++S++     p+    +++vRae+lpSg+li+p+++g+s +++v+h +l+++ ++++lr+l+
  MELO3C025774P1 259 YTQVYAPTTLAPaRDFWTLRYTITLENGSLVVCERSLSGSGAGPSeaaAAQFVRAEMLPSGYLIRPCEGGGSIIHIVDHLNLEAWNVPEVLRPLY 353
                     **************************************88777777999********************************************** PP

                     HHHHHHHHHHHHHHTXXXXX CS
           START 186 ksglaegaktwvatlqrqce 205
                     +s+ + ++k++ a+l++ ++
  MELO3C025774P1 354 ESSKVVAQKMTIAALRYVRQ 373
                     ***************99765 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.6612084IPR001356Homeobox domain
SuperFamilySSF466893.59E-172287IPR009057Homeodomain-like
SMARTSM003892.2E-162288IPR001356Homeobox domain
CDDcd000862.07E-162585No hitNo description
PfamPF000461.2E-162683IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.601.3E-182783IPR009057Homeodomain-like
CDDcd146861.09E-577116No hitNo description
PROSITE profilePS5084826.686155383IPR002913START domain
CDDcd088757.87E-73159375No hitNo description
Gene3DG3DSA:3.30.530.209.2E-20164366IPR023393START-like domain
SMARTSM002341.6E-39164374IPR002913START domain
SuperFamilySSF559611.51E-34164376No hitNo description
PfamPF018521.2E-46165373IPR002913START domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0009956Biological Processradial pattern formation
GO:0010014Biological Processmeristem initiation
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0030154Biological Processcell differentiation
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 541 aa     Download sequence    Send to blast
MAMAIAHHRE SSSGSITRHL DSSGKYVRYT SEQVEALERV YAECPKPSSL RRQQLVRECP  60
ILSNIEPKQI KVWFQNRRCR EKQRKEASRL QTVNRKLNAM NKLLMEENDR LQKQVSQLVC  120
ENGFMRQQLH TVPAAATADA SCDSVVTTPQ PSRRDANNPA GLLSIAEETL AEFLSKATGT  180
AVDWVQMPGM KPGPDSVGIF AISQSCGGVA ARACGLVSLE PSKIAEILKD RPSWFRDCRS  240
LEVFTMFPAG NGGTIELVYT QVYAPTTLAP ARDFWTLRYT ITLENGSLVV CERSLSGSGA  300
GPSEAAAAQF VRAEMLPSGY LIRPCEGGGS IIHIVDHLNL EAWNVPEVLR PLYESSKVVA  360
QKMTIAALRY VRQIAQETSG EVVYGLGRQP AVLRTFSQRL SRGFNDAVNG FNDNGWSLIN  420
CEGAEDVVLT VNSTKNFGTT SNPANSLTFP GGVLCAKASM LLQNIPPAVL VRFLREHRSE  480
WADFNIDAYS AATLKANSYT YPGMRPTRFT GSQIIMPLGH TIEHEEVCFK WHLFLAIHCL  540
*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008463946.10.0PREDICTED: homeobox-leucine zipper protein REVOLUTA isoform X2
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLA0A1S3CLX20.0A0A1S3CLX2_CUCME; homeobox-leucine zipper protein REVOLUTA isoform X2
STRINGXP_008463945.10.0(Cucumis melo)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60690.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]