PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C007121P1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family TCP
Protein Properties Length: 453aa    MW: 49119.1 Da    PI: 9.4509
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C007121P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP115.76e-36852342134
             TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt...............ssssasec...eaess 78 
                      g+kdrhsk+ T++g+RdRRvRls+ +a++f+dLqd+LGf ++sk++eWL+++a  aikel+++                      +   ++++ 
  MELO3C007121P1  85 SGGKDRHSKVWTSKGLRDRRVRLSVATAIQFYDLQDRLGFEQPSKAVEWLIKAAADAIKELPSLnasfpetpkqlsgekF------SvtdQPGTL 173
                     689*************************************************************7777655443333320......123322222 PP

             TCP  79 sssas.nsssgkaaksaakskksqksaasalnlak....esrakarararertrekmrikn 134
                      s ++ +s+ + + +++a+s++s++s+ s l+l++      r kar+ra+er ++++ +++
  MELO3C007121P1 174 DSVEQkQSQLHVSLSKSACSSNSETSKGSGLSLSRsevrVNRLKARERAKERAQKEKEKEQ 234
                     2222212233344555556677777777777777653335669999999996655554443 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036342.4E-4086232IPR005333Transcription factor, TCP
PROSITE profilePS5136931.66287145IPR017887Transcription factor TCP subgroup
PROSITE profilePS513708.617212230IPR017888CYC/TB1, R domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009637Biological Processresponse to blue light
GO:0009965Biological Processleaf morphogenesis
GO:0030154Biological Processcell differentiation
GO:0045962Biological Processpositive regulation of development, heterochronic
GO:1903508Biological Processpositive regulation of nucleic acid-templated transcription
GO:2000306Biological Processpositive regulation of photomorphogenesis
Sequence ? help Back to Top
Protein Sequence    Length: 453 aa     Download sequence    Send to blast
MEVVDNIQEQ PRKFPRLANG RSSDSNEIGL KGAENVRRGD EKDKESKRDG GITGVGGGGV  60
GGADDETNRL RGWHHSRIIR VSRASGGKDR HSKVWTSKGL RDRRVRLSVA TAIQFYDLQD  120
RLGFEQPSKA VEWLIKAAAD AIKELPSLNA SFPETPKQLS GEKFSVTDQP GTLDSVEQKQ  180
SQLHVSLSKS ACSSNSETSK GSGLSLSRSE VRVNRLKARE RAKERAQKEK EKEQDSSRIT  240
DHNLSSMTRN SSFTELLAGG AASVSTHRDA GVAAERQWQS STVAMDYFSS GILEPSTSRT  300
HHSSGFSDQM NLGTSLPQSM SSTPLFSSVS TGDSNAEQLH QFSFVHDGNI VPVATTQPGG  360
GNDYSLNFTI SSNLPGYYRG TLQSNSSLLP HLQRFSPVDG SNLPFLFGAA TSAAPQLENH  420
NHYQFSPAFD GRLQLCYGGG NRQSEQKGKG KD*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5zkt_A7e-2292146155Putative transcription factor PCF6
5zkt_B7e-2292146155Putative transcription factor PCF6
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtPlays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Participates in ovule develpment (PubMed:25378179). Participates in ovule develpment (PubMed:25378179). Promotes light-regulated transcription of CHS, CAB, HYH and HY5. Regulates positively photomorphogenesis (e.g. hypocotyl elongation inhibition and cotyledon opening in response to blue light) (PubMed:26596765). {ECO:0000269|PubMed:12931144, ECO:0000269|PubMed:17307931, ECO:0000269|PubMed:25378179, ECO:0000269|PubMed:26596765}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00006PBMTransfer from 493022Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the miRNA miR-JAW (PubMed:12931144). Induced by blue light. Stabilized by light but labile in darkness due to proteasome-dependent proteolysis (at protein level) (PubMed:26596765). {ECO:0000269|PubMed:12931144, ECO:0000269|PubMed:26596765}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankLN6818750.0LN681875.1 Cucumis melo genomic scaffold, anchoredscaffold00007.
GenBankLN7132620.0LN713262.1 Cucumis melo genomic chromosome, chr_8.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008439614.10.0PREDICTED: transcription factor TCP2-like
RefseqXP_008439615.10.0PREDICTED: transcription factor TCP2-like
RefseqXP_008439616.10.0PREDICTED: transcription factor TCP2-like
SwissprotQ93V432e-78TCP2_ARATH; Transcription factor TCP2
TrEMBLA0A1S3AZT20.0A0A1S3AZT2_CUCME; transcription factor TCP2-like
STRINGXP_008439614.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF40193156
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G18390.29e-73TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 2
Publications ? help Back to Top
  1. Koyama T,Sato F,Ohme-Takagi M
    Roles of miR319 and TCP Transcription Factors in Leaf Development.
    Plant Physiol., 2017. 175(2): p. 874-885
    [PMID:28842549]
  2. Bresso EG,Chorostecki U,Rodriguez RE,Palatnik JF,Schommer C
    Spatial Control of Gene Expression by miR319-Regulated TCP Transcription Factors in Leaf Development.
    Plant Physiol., 2018. 176(2): p. 1694-1708
    [PMID:29133375]