PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C007078P2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family HD-ZIP
Protein Properties Length: 848aa    MW: 92699.7 Da    PI: 6.059
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C007078P2genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox58.41.2e-181876357
                    --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
        Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                    k  ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  MELO3C007078P2 18 KYVRYTPEQVEALERVYAECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 76
                    6789*****************************************************97 PP

2START164.29.4e-521673742204
                     HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlm 94 
                     +aee+++e+++ka+ ++  Wv++  +++g++++ +++ s+++sg a+ra+g+v  +++  v+e+l+d++ W ++++   +l vi +g  g+++l+
  MELO3C007078P2 167 VAEETLAEFLSKATGTAVDWVQMIGMKPGPDSIGIVAVSRNCSGVAARACGLVSLEPT-KVAEILKDRLSWYRDCRCLNVLSVIPTGngGTIELI 260
                     6899******************************************************.8999999999************************** PP

                     EEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHH CS
           START  95 vaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslv 185
                     +++++a+++l++ Rdf++ Ry+ +l++g++v++++S++s +  p     s +vRae+lpSg+li+ +++g+s +++v+h+dl+ ++++++lr+l+
  MELO3C007078P2 261 YMQTYAPTTLAAaRDFWTMRYTTSLEDGSLVVCERSLSSSSGGPAgppPSTFVRAEMLPSGYLIRACEGGGSIIHIVDHIDLDVWSVPEVLRPLY 355
                     ***************************************999888877899******************************************** PP

                     HHHHHHHHHHHHHHTXXXX CS
           START 186 ksglaegaktwvatlqrqc 204
                     +s+ + ++k++ a+l++ +
  MELO3C007078P2 356 ESSKILAQKITIAALRHIR 374
                     **************99865 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.711377IPR001356Homeobox domain
SMARTSM003898.0E-161581IPR001356Homeobox domain
PfamPF000463.1E-161876IPR001356Homeobox domain
SuperFamilySSF466891.88E-161879IPR009057Homeodomain-like
CDDcd000861.14E-161878No hitNo description
Gene3DG3DSA:1.10.10.601.5E-182076IPR009057Homeodomain-like
CDDcd146863.81E-670109No hitNo description
PROSITE profilePS5084823.648157385IPR002913START domain
CDDcd088752.16E-68161377No hitNo description
SMARTSM002341.5E-46166376IPR002913START domain
Gene3DG3DSA:3.30.530.203.9E-21166352IPR023393START-like domain
PfamPF018524.3E-49167374IPR002913START domain
SuperFamilySSF559619.48E-36167378No hitNo description
PfamPF086704.1E-50702846IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009880Biological Processembryonic pattern specification
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0010072Biological Processprimary shoot apical meristem specification
GO:0080060Biological Processintegument development
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 848 aa     Download sequence    Send to blast
MALVIHKDTS NKQMDSSKYV RYTPEQVEAL ERVYAECPKP SSLRRQQLIR ECPILSNIEP  60
KQIKVWFQNR RCREKQRKES SRLQSVNRKL SAMNKLLMEE NDRLQKQVSH LVYENGFMRQ  120
QLHSASGTTT DNSCESVVMS GQPQQQQNPN PQHPNRDVNN PAGLLAVAEE TLAEFLSKAT  180
GTAVDWVQMI GMKPGPDSIG IVAVSRNCSG VAARACGLVS LEPTKVAEIL KDRLSWYRDC  240
RCLNVLSVIP TGNGGTIELI YMQTYAPTTL AAARDFWTMR YTTSLEDGSL VVCERSLSSS  300
SGGPAGPPPS TFVRAEMLPS GYLIRACEGG GSIIHIVDHI DLDVWSVPEV LRPLYESSKI  360
LAQKITIAAL RHIRQIAQET NGEIQCTGGR QPAVLRTFSQ KLCRGFNDAV NGFADDGWSP  420
MGSDGVEDVT ILINTSANKF SGSQYNTSLY PSFGGGVMCA KASMLLQNVP PALLVRFLRE  480
HRSEWADYGV DAYSAASLKA SPYAVPCARP GGFPSSQVIL PLATTVEHEE FLEVVRLEGL  540
AFSPEDVALA GRDMYLLQLC SGVDENAVGA CAQLVFAPID ESFADDAPLL PSGFRVIPLD  600
PKTDEPTAAR TLDLASTLEV GANAARSAGE TDLSSYNLRS VLTIAFQFTF ENHLQENVAA  660
MARQYVRSVV GSVQRVAMAI SPSRLSSNMG LKPLPGSPEA LTLARWICRS YRIHVGAELL  720
QADSQSGDAM LKQLWHHSDA IMCCSVKTNA SAVFTFANQA GLDMLETTLV GLQDIMLDKI  780
LDEAGRKILC SEFPKIMQQG FANLPSGICV SSMGRPISYE QAVAWKVLND DDSNHCLAFM  840
FINWSFV*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates. Binds to the DNA sequence 5'-GTAAT[GC]ATTAC-3'. {ECO:0000269|PubMed:11395776, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:17900520, ECO:0000269|PubMed:9747806}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00170DAPTransfer from AT1G30490Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by miR165 and miR166. {ECO:0000269|PubMed:14999284, ECO:0000269|PubMed:16033795, ECO:0000269|PubMed:17237362}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008439554.10.0PREDICTED: homeobox-leucine zipper protein ATHB-14-like
SwissprotO042920.0ATBH9_ARATH; Homeobox-leucine zipper protein ATHB-9
TrEMBLA0A1S3AZP60.0A0A1S3AZP6_CUCME; homeobox-leucine zipper protein ATHB-14-like
STRINGXP_008439554.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF51763353
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G34710.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  2. Yamada T,Sasaki Y,Hashimoto K,Nakajima K,Gasser CS
    CORONA, PHABULOSA and PHAVOLUTA collaborate with BELL1 to confine WUSCHEL expression to the nucellus in Arabidopsis ovules.
    Development, 2016. 143(3): p. 422-6
    [PMID:26700684]
  3. Wójcik AM,Nodine MD,Gaj MD
    miR160 and miR166/165 Contribute to the LEC2-Mediated Auxin Response Involved in the Somatic Embryogenesis Induction in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 2024
    [PMID:29321785]