PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID MELO3C003468P1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Benincaseae; Cucumis
Family HD-ZIP
Protein Properties Length: 843aa    MW: 92490.8 Da    PI: 6.1403
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
MELO3C003468P1genomeMELONOMICSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox59.36.3e-192280357
                    --SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
        Homeobox  3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                    k  ++t+eq+e+Le+l++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  MELO3C003468P1 22 KYVRYTPEQVEALERLYYECPKPSSMRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 80
                    5679*****************************************************97 PP

2START175.63e-551663732204
                     HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlm 94 
                     +aee+++e+++ka+ ++  Wv+++ +++g++++ +++ s++++g a+ra+g+v  +++  v+e+l+d + W ++++++++l+v+s+g  g+++l 
  MELO3C003468P1 166 IAEETLAEFLSKATGTAVEWVQMPGMKPGPDSIGIVAISHGCTGVAARACGLVGLEPT-RVAEILKDWPSWFRDCRAVDVLNVLSTGngGTIELL 259
                     7899******************************************************.9999999999************************** PP

                     EEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHH CS
           START  95 vaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslv 185
                     +++l+a+++l+p Rdf+ +Ry+  l++g++v++++S++++q+ p+    +++vRae+lpSg+li+p+++g+s +++v+h+dl+  +++++lr+l+
  MELO3C003468P1 260 YMQLYAPTTLAPaRDFWLLRYTSVLEDGSLVVCERSLNNTQNGPSmppVQNFVRAEMLPSGYLIRPCEGGGSIIHIVDHMDLEPCSVPEVLRPLY 354
                     *******************************************9988899********************************************* PP

                     HHHHHHHHHHHHHHTXXXX CS
           START 186 ksglaegaktwvatlqrqc 204
                     ks++  ++k+++a+l+ ++
  MELO3C003468P1 355 KSSTLLAQKNTMAALRLLR 373
                     ***************9876 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5007115.6131781IPR001356Homeobox domain
SMARTSM003893.4E-151985IPR001356Homeobox domain
SuperFamilySSF466898.55E-172184IPR009057Homeodomain-like
CDDcd000863.69E-162282No hitNo description
PfamPF000461.6E-162380IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.605.2E-182480IPR009057Homeodomain-like
CDDcd146861.30E-674113No hitNo description
PROSITE profilePS5084825.437156370IPR002913START domain
CDDcd088753.10E-80160375No hitNo description
SMARTSM002346.2E-41165375IPR002913START domain
SuperFamilySSF559611.11E-36165375No hitNo description
Gene3DG3DSA:3.30.530.202.5E-22165370IPR023393START-like domain
PfamPF018521.5E-52166374IPR002913START domain
PfamPF086703.0E-50701841IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010067Biological Processprocambium histogenesis
GO:0010072Biological Processprimary shoot apical meristem specification
GO:0010089Biological Processxylem development
GO:0045597Biological Processpositive regulation of cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 843 aa     Download sequence    Send to blast
MMAVTSACKD AASKMSSLDN GKYVRYTPEQ VEALERLYYE CPKPSSMRRQ QLIRECPILS  60
NIEPKQIKVW FQNRRCREKQ RKEASRLQTV NRKLTAMNRL LMEENDRLQK QVSQLVYENS  120
YFRQQTQNAT LATTDTSCES VVTSGQQNLT PPHPPKDASP AGLLSIAEET LAEFLSKATG  180
TAVEWVQMPG MKPGPDSIGI VAISHGCTGV AARACGLVGL EPTRVAEILK DWPSWFRDCR  240
AVDVLNVLST GNGGTIELLY MQLYAPTTLA PARDFWLLRY TSVLEDGSLV VCERSLNNTQ  300
NGPSMPPVQN FVRAEMLPSG YLIRPCEGGG SIIHIVDHMD LEPCSVPEVL RPLYKSSTLL  360
AQKNTMAALR LLRQISQEVS QPNVTGWGRR PAALRALSQK LSRGFNEAVN GFTDEGWSLL  420
ENDGVDDVTL LVNMSHGKTM MGANISYSNG FPSMSNAVLC AKASMLLQNV TPAMLIRFLR  480
EHRSEWADSS IDAYSAAAIR TGQCGLPGSH AGTFGGQVIL PLAQTVEHEE FMEVVKFENV  540
GHYRDDMLMP GDIFLLQLCN GVDENAVGTS AELIFAPIDA SFSDDAPILP SGFRIIPLDS  600
GMDASSPNRT LDLASALDVG PAGNRASGDC AGQSGKSKSV MTIAFQFVFD VHLQDNVAAM  660
ARQYVRSIIA SVQRVALALS PSNFGPHANL QTPAGAPEAH TLARWISQSY RCYMGMELLK  720
NEGRESILKS LWHHSDAVMC CSLKALPNFT FANQSGLDML ETTLVALQDI TLEKIFDDNG  780
KKTLASEFPR IMQQGFICLQ GGVCLSSMGR AVSYEKAVAW KVLNEEENAH CICFMFMNWS  840
FV*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. {ECO:0000269|PubMed:11402194, ECO:0000269|PubMed:15598805}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by miR165. {ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:8575317}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008466070.10.0PREDICTED: homeobox-leucine zipper protein ATHB-8
SwissprotQ391230.0ATHB8_ARATH; Homeobox-leucine zipper protein ATHB-8
TrEMBLA0A1S3CRT50.0A0A1S3CRT5_CUCME; homeobox-leucine zipper protein ATHB-8
STRINGXP_008466070.10.0(Cucumis melo)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19463387
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G32880.10.0homeobox gene 8
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Hategan L,Godza B,Kozma-Bognar L,Bishop GJ,Szekeres M
    Differential expression of the brassinosteroid receptor-encoding BRI1 gene in Arabidopsis.
    Planta, 2014. 239(5): p. 989-1001
    [PMID:24488524]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Kakehi J, et al.
    Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana.
    PLoS ONE, 2015. 10(1): p. e0117309
    [PMID:25625317]
  5. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  6. Liu S, et al.
    Expression of wild-type PtrIAA14.1, a poplar Aux/IAA gene causes morphological changes in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 388
    [PMID:26082787]
  7. Yamaguchi YL, et al.
    Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis Roots.
    Front Plant Sci, 2017. 8: p. 1195
    [PMID:28747918]
  8. Yamazaki K, et al.
    Suppression of DELLA signaling induces procambial cell formation in culture.
    Plant J., 2018. 94(1): p. 48-59
    [PMID:29383774]