PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cagra.0686s0024.1.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family C2H2
Protein Properties Length: 256aa    MW: 28891.4 Da    PI: 9.1312
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cagra.0686s0024.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H216.13.3e-0588110123
                          EEETTTTEEESSHHHHHHHHHHT CS
              zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                          y+C++C + F+++  L  H++ H
  Cagra.0686s0024.1.p  88 YECHYCFRNFPTSQALGGHQNAH 110
                          99******************988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.31E-684115No hitNo description
PfamPF139121.8E-587112IPR007087Zinc finger, C2H2
PROSITE profilePS5015711.17788115IPR007087Zinc finger, C2H2
PROSITE patternPS00028090110IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009739Biological Processresponse to gibberellin
GO:0010091Biological Processtrichome branching
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 256 aa     Download sequence    Send to blast
MDEATGETET QDFMNVESFS QLPFIRRPKD QNPKPIRVFG KDFTDGDLSG TTRQEYYPDP  60
SQNKNKEEED QTGDNDKDNT SISNNRRYEC HYCFRNFPTS QALGGHQNAH KRERQLAKRG  120
VSSYFHHPDT SLYTSYRHYP SWSSSPFTAA RSYGRHFSSL HSSAYYTRRP SYGSPLGLWR  180
RPRTSPSGLQ SIYSSNATFT GSNFSSNSTL SLLAGSQPQP PLQLGGPSSH QIRASSYRYG  240
LSPNVQDHVS LDLHL*
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin (GA) (PubMed:16679458, PubMed:17507408). Mediates the induction of GL1 expression by GA in inflorescence organs and is antagonized in its action by the DELLA repressor GAI. Acts upstream of the trichome initiation regulators GL1 and GL3, and downstream of the GA signaling repressor SPINDLY (SPY) (PubMed:16679458). Does not play a significant role in the cytokinin response (PubMed:17507408). Controls trichome branching through GA signaling (PubMed:22210898, PubMed:23825141). Acts downstream of the key regulator STICHEL (STI) in an endoreduplication-independent pathway (PubMed:22210898). Controls trichome cell division indirectly by acting downstream of a key endoreduplication regulator SIAMESE (SIM) (PubMed:23825141). {ECO:0000269|PubMed:16679458, ECO:0000269|PubMed:17507408, ECO:0000269|PubMed:22210898, ECO:0000269|PubMed:23825141}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapCagra.0686s0024.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By gibberellin. {ECO:0000269|PubMed:16679458}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAL1329771e-125AL132977.1 Arabidopsis thaliana DNA chromosome 3, BAC clone T10K17.
GenBankAL1370811e-125AL137081.1 Arabidopsis thaliana DNA chromosome 3, BAC clone F9D24.
GenBankBT0033401e-125BT003340.1 Arabidopsis thaliana zinc finger-like protein (At3g58070) mRNA, complete cds.
GenBankBT0096761e-125BT009676.1 Arabidopsis thaliana At3g58070 mRNA, complete cds.
GenBankCP0026861e-125CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006292550.10.0zinc finger protein GIS
SwissprotQ84WI01e-116GIS_ARATH; Zinc finger protein GIS
TrEMBLR0HNG80.0R0HNG8_9BRAS; Uncharacterized protein
STRINGCagra.0686s0024.1.p0.0(Capsella grandiflora)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM24951949
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G58070.11e-106C2H2 family protein
Publications ? help Back to Top
  1. Sun L, et al.
    GLABROUS INFLORESCENCE STEMS3 (GIS3) regulates trichome initiation and development in Arabidopsis.
    New Phytol., 2015. 206(1): p. 220-30
    [PMID:25640859]
  2. Yu D, et al.
    RPN1a, a subunit of the 26S proteasome, controls trichome development in Arabidopsis.
    Plant Physiol. Biochem., 2015. 88: p. 82-8
    [PMID:25676129]
  3. Liu Y, et al.
    AtGIS, a C2H2 zinc-finger transcription factor from Arabidopsis regulates glandular trichome development through GA signaling in tobacco.
    Biochem. Biophys. Res. Commun., 2017. 483(1): p. 209-215
    [PMID:28034756]
  4. Vadde BVL,Challa KR,Nath U
    The TCP4 transcription factor regulates trichome cell differentiation by directly activating GLABROUS INFLORESCENCE STEMS in Arabidopsis thaliana.
    Plant J., 2018. 93(2): p. 259-269
    [PMID:29165850]
  5. Kim SY,Hyoung S,So WM,Shin JS
    The novel transcription factor TRP interacts with ZFP5, a trichome initiation-related transcription factor, and negatively regulates trichome initiation through gibberellic acid signaling.
    Plant Mol. Biol., 2018. 96(3): p. 315-326
    [PMID:29335898]