PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cagra.0053s0018.1.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella
Family ARR-B
Protein Properties Length: 678aa    MW: 74187.1 Da    PI: 6.4693
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cagra.0053s0018.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like90.81.2e-28210263155
              G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                          kpr++W+ eLH++Fv av+qL G +kA+Pk+ile+m+v+gLt+e+v+SHLQkYR+
  Cagra.0053s0018.1.p 210 KPRVVWSVELHQQFVAAVNQL-GVDKAVPKKILEMMNVPGLTRENVASHLQKYRI 263
                          79*******************.********************************7 PP

2Response_reg76.41e-25251331109
                          EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHH CS
         Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedale 88 
                          vl+vdD+p+ +++l+++l+   y +v+ +  +e al ll++++  +D+++ D+ mp+mdG++ll++   e  +lp+i+++a ++++ +l+
  Cagra.0053s0018.1.p  25 VLVVDDDPTCLMILERMLRTCLY-RVTKCNRAEIALSLLRKNKngFDIVISDVHMPDMDGFKLLEHVGLEM-DLPVIMMSADDSKSVVLK 112
                          89*********************.***************999889**********************6644.8***************** PP

                          HHHTTESEEEESS--HHHHHH CS
         Response_reg  89 alkaGakdflsKpfdpeelvk 109
                           +  Ga d+l Kp+ +e+l +
  Cagra.0053s0018.1.p 113 GVTHGAVDYLIKPVRIEALKN 133
                          *****************9986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363927.8E-2007669IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23007.8E-4122169No hitNo description
SuperFamilySSF521721.01E-3422146IPR011006CheY-like superfamily
SMARTSM004481.4E-2923135IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011041.44124139IPR001789Signal transduction response regulator, receiver domain
PfamPF000721.1E-2225133IPR001789Signal transduction response regulator, receiver domain
CDDcd001565.86E-2726138No hitNo description
PROSITE profilePS5129411.323207266IPR017930Myb domain
SuperFamilySSF466897.53E-20208267IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.606.3E-30209268IPR009057Homeodomain-like
TIGRFAMsTIGR015572.9E-24210263IPR006447Myb domain, plants
PfamPF002491.1E-8212262IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009873Biological Processethylene-activated signaling pathway
GO:0010082Biological Processregulation of root meristem growth
GO:0010119Biological Processregulation of stomatal movement
GO:0010150Biological Processleaf senescence
GO:0071368Biological Processcellular response to cytokinin stimulus
GO:0080113Biological Processregulation of seed growth
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 678 aa     Download sequence    Send to blast
MINPGHGRGP DSGSNSDPFP AGLRVLVVDD DPTCLMILER MLRTCLYRVT KCNRAEIALS  60
LLRKNKNGFD IVISDVHMPD MDGFKLLEHV GLEMDLPVIM MSADDSKSVV LKGVTHGAVD  120
YLIKPVRIEA LKNIWQHVVR KKRNEWNVSE HSGGSLEDTG GDRDRQQQRE DADNNSSSVN  180
EGNWRSSRKR KEEEVDDQGD DKEDTSSLKK PRVVWSVELH QQFVAAVNQL GVDKAVPKKI  240
LEMMNVPGLT RENVASHLQK YRIYLRRLGG VSQHQGNMNH SFMTGQDPSY GPLSSLNGFD  300
LQALAVAGQL PAQSLAQLQA AGLGRPSLTK PGMSVSPLVD QRSIFNFENP KIRFGDGHGQ  360
TINNGNKQMN LLHGVPTGME PKQFAGSHMR VQQQIAGVRP GQNVQSSGMM LPVTDQLPRG  420
GPSMLPSLGQ QPMLSSSVSR RSDLTGAVAV RTSIPETNNR MLPATHSVFN NFSADLPQNS  480
FPLASAPGIS IPVSASYQEE VSSSDAKGGS SAATMATAGF GNPSYDIFND FPQQQQQNNN  540
INNRLNDWDL RNIGLVFSHQ DAAAASAAFS TSDAYSSPST QRKRRETDAT VVADQGQNQQ  600
PPSRNMNHLN NVYMDGGSVR VKSERVAETM TCPPATTLFH EQYNQEDLMS ALLKQEGIPT  660
VDNEFDFDGY SVDNIPV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A6e-22206268163ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00054PBMTransfer from AT4G16110Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapCagra.0053s0018.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankDQ4735210.0DQ473521.1 Arabidopsis thaliana ARR2 (ARR2) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006286049.20.0two-component response regulator ARR2
SwissprotQ9ZWJ90.0ARR2_ARATH; Two-component response regulator ARR2
TrEMBLR0FAB40.0R0FAB4_9BRAS; Two-component response regulator
STRINGCagra.0053s0018.1.p0.0(Capsella grandiflora)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM24032773
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.10.0response regulator 2
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]