PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cc01_g18590
Common NameGSCOC_T00016185001
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Rubiaceae; Ixoroideae; Coffeeae; Coffea
Family bHLH
Protein Properties Length: 471aa    MW: 52094.4 Da    PI: 5.4082
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cc01_g18590genomeCGSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.16.8e-13324370455
                  HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
          HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                  +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  Cc01_g18590 324 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITDLQ 370
                  799***********************66......*****************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.9E-4449227IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.806320369IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.44E-18323388IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000839.14E-15323374No hitNo description
Gene3DG3DSA:4.10.280.103.6E-18324389IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.2E-10324370IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.4E-15326375IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 471 aa     Download sequence    Send to blast
MGEKFWLIEE DKALVESVLG AEAVQFFVWL ASSNILSEFA APAGVAGVQD GLSKVVEGSD  60
WTYAIYWQVS TSKSGKSALI WGDGHCRDPR GTEKMDGNDY RDQRFAGGDR RKQALQKIHA  120
CFGGAEDDNV AAKLDSVSEL EMFYLTSMYY AFPFDKPSTP SQAFNTSRTI WVSDPRSCSE  180
NYQSRASLAK SARIETVVFV PFKSGVVEIG SGKSLSEDPN VVQMVKTSIT PNVVHPKTAP  240
KIFGQELSLG GGKSGPISIS FSPKVEDDSL FVSDSYELQA LAGYGPSNGY RSDDGEDDSL  300
MLSDDRRPRK RGRKPANGRE EPLNHVEAER QRREKLNQRF YALRAVVPNI SKMDKASLLG  360
DAIAYITDLQ KKIRIMEAER EMVNDRQKQP AVTDIDLQER HEDAVVQVSC PLDVHPVSRV  420
IKAMREHQIV AQESDVSLTE NGEVVHTFSI RTQGGDAEHL KEKLTTALFN *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A1e-28318386270Transcription factor MYC2
5gnj_B1e-28318386270Transcription factor MYC2
5gnj_E1e-28318386270Transcription factor MYC2
5gnj_F1e-28318386270Transcription factor MYC2
5gnj_G1e-28318386270Transcription factor MYC2
5gnj_I1e-28318386270Transcription factor MYC2
5gnj_M1e-28318386270Transcription factor MYC2
5gnj_N1e-28318386270Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1305313RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00099PBMTransfer from AT4G16430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027095370.10.0transcription factor bHLH3
SwissprotA0A3Q7H2160.0MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A068U6220.0A0A068U622_COFCA; Uncharacterized protein
STRINGXP_009631111.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA66692433
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-151bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]