PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ciclev10003783m
Common NameCICLE_v10003783mg
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus
Family C2H2
Protein Properties Length: 371aa    MW: 42590.3 Da    PI: 6.6733
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Ciclev10003783mgenomeICGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.80.000187698323
                     ET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2  3 Cp..dCgksFsrksnLkrHirtH 23
                     C+   Cgk+F +  +L++H   H
  Ciclev10003783m 76 CSyeGCGKTFIDAASLRKHAHIH 98
                     77779**************9877 PP

2zf-C2H216.23e-05103127123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      y+C+   Cgk F ++s LkrH   H
  Ciclev10003783m 103 YQCHyeGCGKKFLDSSKLKRHFLIH 127
                      9********************8877 PP

3zf-C2H222.43.2e-07133157123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      y+Cp   Cgk Fs   nL++H++tH
  Ciclev10003783m 133 YVCPheGCGKAFSLDFNLRSHMKTH 157
                      99**********************9 PP

4zf-C2H217.89.3e-06163187123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      + Cp  dCgk++ + + Lk+Hi +H
  Ciclev10003783m 163 HICPypDCGKRYAHEYKLKNHIASH 187
                      679999*****************96 PP

5zf-C2H2130.00031226251123
                      EEET..TTTEEESSHHHHHHHHHH.T CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                      y Cp   C k + + + Lk H+++ H
  Ciclev10003783m 226 YACPyeGCEKAYIHEYKLKLHLKReH 251
                      89*********************999 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.609.3E-146999IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.07474103IPR007087Zinc finger, C2H2
SMARTSM003550.00467498IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002807698IPR007087Zinc finger, C2H2
SuperFamilySSF576672.36E-877127No hitNo description
Gene3DG3DSA:3.30.160.602.9E-13100122IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015714.17103132IPR007087Zinc finger, C2H2
SMARTSM003550.0017103127IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280105127IPR007087Zinc finger, C2H2
SuperFamilySSF576673.21E-14114166No hitNo description
Gene3DG3DSA:3.30.160.602.1E-20123157IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.882133162IPR007087Zinc finger, C2H2
SMARTSM003551.7E-4133157IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280135157IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.4E-9158189IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.473163192IPR007087Zinc finger, C2H2
SMARTSM003550.0028163187IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280165188IPR007087Zinc finger, C2H2
SuperFamilySSF576671.08E-5221249No hitNo description
Gene3DG3DSA:3.30.160.604.5E-9222248IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.66226256IPR007087Zinc finger, C2H2
SMARTSM003550.012226251IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280228251IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 371 aa     Download sequence    Send to blast
METHFTHSYF ERRPIVKSKT PAVKWFREWV PQDIAATGGK CQILRWKTLK ALKEKAKEPE  60
APEPEPEPTT EVLFLCSYEG CGKTFIDAAS LRKHAHIHGE RQYQCHYEGC GKKFLDSSKL  120
KRHFLIHTGE RDYVCPHEGC GKAFSLDFNL RSHMKTHSQE NYHICPYPDC GKRYAHEYKL  180
KNHIASHHEK NAAVEVPRYA TPPERITKTP KPPAGVYGSA SSERPYACPY EGCEKAYIHE  240
YKLKLHLKRE HPGHMSDENA ENATTNADNE MDEGSDQDAY AGKRVNGKSQ KQSRAKPNLK  300
MPPAKVTQRK SSTPSPATLN VVRKQQWTPK EEVYEEEDSE ETEEDRDNVE DGFRYGENNE  360
DDDEETEYED *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C5e-34761878119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269|PubMed:26961720}.
UniprotTISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269|PubMed:26961720}.
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024949722.10.0zinc finger transcription factor YY1-like
SwissprotQ2V3L31e-157Y4634_ARATH; Uncharacterized zinc finger protein At4g06634
TrEMBLV4UZR70.0V4UZR7_9R
STRINGPOPTR_0004s23050.10.0(Populus trichocarpa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM58592846
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-143C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]