PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID C.cajan_17204
Common NameKK1_017714
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Cajanus
Family E2F/DP
Protein Properties Length: 500aa    MW: 54874.6 Da    PI: 4.9403
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
C.cajan_17204genomeIIPGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.77.2e-27182247171
        E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                    r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  C.cajan_17204 182 RYDSSLGLLTKKFINLVKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 247
                    6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.3E-29179249IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.2E-34182247IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467857.35E-17182245IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.9E-24184247IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146606.26E-48260364No hitNo description
SuperFamilySSF1440742.88E-32260364No hitNo description
PfamPF164212.6E-33263362IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 500 aa     Download sequence    Send to blast
MSSAAGAPDR RASPPQGAAG AASRPPLKRH LAFATKPPFA PPDEYHSFST PDSRRVADEA  60
VVVRSPFLLS LLLISFCLCS LSSRIWNVPF RLCGCDSLWF SYMKRKSGMN DTEGESQAQK  120
WSNSPGYTNV SNITSSPFKT PVSAKGGRTQ KAKASKEGRS CPPTPISNAG SPSPLTPASS  180
CRYDSSLGLL TKKFINLVKH AEDGILDLNK AAETLEVQKR RIYDITNVLE GIGLIEKKLK  240
NRIHWKGIES STSGEVDGDI SVLKAEVDKL TLEEQGLDDQ IREMQERLRN LSENENNQKC  300
LFVTEDDIKG LPCFQNETLI AIKAPHGTTL EVPDPEEAVD YPQRRYRIIL RSTMGPIDVY  360
LISQFEEKFE EINGAEHPMI PLASSSGSNE QLLTEMVPAD GKELETQTQL SSHAYSDLNA  420
SQEFAGGMMK IVPSDVDNDA DYWLLSDADV SITDMWRTDS TVDWNGVDIL HSDFGIVSRP  480
QTPSSGFAEV PPTGANSSQK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A6e-25177248274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00293DAPTransfer from AT2G36010Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapC.cajan_17204
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0930461e-108BT093046.1 Soybean clone JCVI-FLGm-15I8 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020221307.10.0transcription factor E2FA isoform X2
SwissprotQ9FNY01e-155E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A151T7V50.0A0A151T7V5_CAJCA; Transcription factor E2F3
STRINGGLYMA02G35850.10.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-147E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]