PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID CA03g27290
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum
Family E2F/DP
Protein Properties Length: 385aa    MW: 43241.9 Da    PI: 8.7355
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
CA03g27290genomePEPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP74.79.4e-241782171
     E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                rk+ksL+ll+++fl+l++++  +++ l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  CA03g27290 17 RKQKSLGLLCSNFLSLYNREGVETIGLDDAARRL---GV--ERRRIYDIVNVLESIGVLARKAKNRYSWKG 82
                79*****************999************...**..****************************98 PP

2E2F_TDP74.79.4e-24151231171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                 r+eksL+lltq+f+kl+ +++ ++++l+e+ak L+ +      +++k+RR+YDi+NVL++++ iek     ++k+++rw g
  CA03g27290 151 RREKSLGLLTQNFVKLFLCTNVDMICLDEAAKILLGDgrppaMTRTKVRRLYDIANVLSSMKFIEKthhpeTRKPAFRWLG 231
                 689**************************************99999*********************99999*******87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.5E-261383IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467858.44E-161780IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.5E-281782IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.2E-201882IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.106.8E-23148232IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.4E-31151231IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.9E-11153232IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023195.3E-18153231IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 385 aa     Download sequence    Send to blast
MALTLDPSKD SRSTYCRKQK SLGLLCSNFL SLYNREGVET IGLDDAARRL GVERRRIYDI  60
VNVLESIGVL ARKAKNRYSW KGFGAIPRTL EQLKEEGLKD NGSGFDGSSS VKGSDDDDDD  120
RDSNLIDSSQ TDKLNPNSGV NSAGPFKSEN RREKSLGLLT QNFVKLFLCT NVDMICLDEA  180
AKILLGDGRP PAMTRTKVRR LYDIANVLSS MKFIEKTHHP ETRKPAFRWL GLRERSEDKS  240
VDALCANESK KRVFGSDLTN STIKRSRVGL PMDGISDEAT RIQLLTEVKC ENPENDFHIP  300
KQEPGLTSSK KSYHFGPFAP PTIPPAEVSQ SDRMKRVHDW ESLASNYHPQ YHNQALKDLF  360
AHYVEAWKSW YLEVAGKNPI QLIS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-35172234228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9755151e-148HG975515.1 Solanum lycopersicum chromosome ch03, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016563525.10.0PREDICTED: E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-122E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A1U8FXH90.0A0A1U8FXH9_CAPAN; E2F transcription factor-like E2FE
TrEMBLA0A2G2Y7020.0A0A2G2Y702_CAPAN; E2F transcription factor-like E2FE
STRINGSolyc03g113760.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA25222457
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-120DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]