PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID CA00g72950
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum
Family AP2
Protein Properties Length: 656aa    MW: 72477.4 Da    PI: 7.6912
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
CA00g72950genomePEPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP231.83.5e-10303369155
         AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng........kr..krfslgkfgtaeeAakaaiaarkkleg 55 
                 s+y+GV++++++gr++A+++d  ++  g         +    ++lg ++ +++Aa+a+++a++k++g
  CA00g72950 303 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqtrkgrqaLNykMMWNLGGYDMEDKAARAYDQAALKYWG 369
                 78*******************98888445666766633557899******99*************98 PP

2AP2461.3e-14412463155
         AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                 s y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  CA00g72950 412 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDVAAIKFRG 463
                 57****************988532...5************************997 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541715.04E-12303379IPR016177DNA-binding domain
CDDcd000181.61E-17303377No hitNo description
PfamPF008478.7E-6303369IPR001471AP2/ERF domain
SMARTSM003807.4E-23304383IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.9E-13304378IPR001471AP2/ERF domain
PROSITE profilePS5103216.107304377IPR001471AP2/ERF domain
PRINTSPR003673.1E-6305316IPR001471AP2/ERF domain
PfamPF008475.2E-10412463IPR001471AP2/ERF domain
CDDcd000186.10E-26412473No hitNo description
SuperFamilySSF541717.85E-18412473IPR016177DNA-binding domain
SMARTSM003801.1E-34413477IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.8E-18413471IPR001471AP2/ERF domain
PROSITE profilePS5103219.124413471IPR001471AP2/ERF domain
PRINTSPR003673.1E-6453473IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 656 aa     Download sequence    Send to blast
MKMKSMNDDS SSSNNSNSNN NNHSSAATNS NNWLGFSLSP HMKMEVTNAS ETQQQHPHQQ  60
QFAQSFYLSS SPTTMNVSTA SALCYENNPF HSSLSVMPLK SDGSLCIMEA LSRSHADAMV  120
QSSSPKLEDF LGGASQYGSH EREAMALSLD SLYYHQNDED IQVHSHHPYY SPMHCHGMYQ  180
ESLLEETKPT QISNCDAQMT GNEMKSWGHY AIDQHINDTC SMVAAAAVAA GGGGGGTVGC  240
NDLQSLSLSM NPGTQSSCVT PRQISPTGLE CVAIESKKRA SAKVAQKQPV HRKSIDTFGQ  300
RTSQYRGVTR HRWTGRYEAH LWDNSCKKEG QTRKGRQALN YKMMWNLGGY DMEDKAARAY  360
DQAALKYWGP STHINFPLEN YQKELEEMKN MTRQEYVAHL RRKSSGFSRG ASIYRGVTRH  420
HQHGRWQARI GRVAGNKDLY LGTFSTQEEA AEAYDVAAIK FRGVNAVTNF DISRYDVEKI  480
MASNNLPAGE LARRTKEREP RESIEYNNIS VHKNEECVQN NNNNGNITDW KMVLYQASNP  540
SIGSNNYRNP SFSVALQDLI GIDSINNSTS HATILDHEQN KIGANHFSNA SSLVTSLGSS  600
REASPDKTAA SLVFAKPTKF VVPTTNVNAC IPSAQLRPIP VSMAHLPVFA ALNDA*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB1812030.0AB181203.1 Solanum lycopersicum LeANT mRNA for AINTEGUMENTA homolog, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016568915.10.0PREDICTED: AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389141e-158ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A2G2Z8480.0A0A2G2Z848_CAPAN; AP2-like ethylene-responsive transcription factor ANT
STRINGPGSC0003DMT4000125880.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA20742460
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-157AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]