PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID CA00g07140
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum
Family E2F/DP
Protein Properties Length: 475aa    MW: 52206.4 Da    PI: 4.5044
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
CA00g07140genomePEPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.32.3e-27149214171
     E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                 r+++sL+llt+kf++l++++e+g+++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  CA00g07140 149 RYDSSLGLLTKKFINLIKHAEDGMLDLNQAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 214
                 6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.4E-29147216IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.6E-34149214IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.45E-17149212IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.4E-24151214IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440742.88E-33229331No hitNo description
PfamPF164213.8E-33230329IPR032198E2F transcription factor, CC-MB domain
CDDcd146604.71E-47230331No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 475 aa     Download sequence    Send to blast
MTASFVTNED YHRFCTPWVV DSSRIDSLQP DAIVVKSPAL FVAHEDFHRF STPGVVDSSR  60
VDSLQPDAIV VKSPALKRKT GYIKEVESSI CTANSGYADV ANSPLGTPVS GKGGRAHGQL  120
RATKSNKSGP PTPAFNAGSP SPLTPASCRY DSSLGLLTKK FINLIKHAED GMLDLNQAAD  180
TLEVQKRRIY DITNVLEGIG LIEKKLKNRI QWKGVDASKP GGVDNDAAIL KANIDSLSME  240
ERRLDERIRE MQEKLRDMSE DENNQRWLFV TEDDIKSLPC FQNETLIAVK APHGTTLEVP  300
DPDEAVDYPQ RRYRIILRST MGPIDVYLVS QFEEKFEEMN GFEPSTTIPD ASSSGSKDYP  360
AVEISTVSNN VTENEGQTQN VDQLSSDVGT SQDYGGGMMK ILPSDVDDAA DYLFLSDPNV  420
SMTDMWKNDC ILVSTVWDGE SLLRDFEIDD LASPRPHTPS SNADVPAPMN IPPR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-25142215274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC2397387e-85AC239738.5 Solanum lycopersicum strain Heinz 1706 chromosome 1 clone hba-240p19 map 1, complete sequence.
GenBankHG9754407e-85HG975440.1 Solanum pennellii chromosome ch01, complete genome.
GenBankHG9755137e-85HG975513.1 Solanum lycopersicum chromosome ch01, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016561923.10.0PREDICTED: transcription factor E2FA, partial
SwissprotQ9FNY01e-138E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A1U8FZY20.0A0A1U8FZY2_CAPAN; transcription factor E2FA
STRINGPGSC0003DMT4000423470.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10772484
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-142E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]